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  • Alzheimer's disease  (1)
  • MBC, microbial biomass carbon MEP, Mehlich extractable phosphorus MLRA, Major Land Resource Areas MWD, mean-weight diameter NRCS, Natural Resources Conservation Service NRI, National Resource Inventory PMN, potentially mineralizable nitrogen PSU, primary sampling units TOC, total organic carbon WSA, water stable aggregates  (1)
  • 2000-2004  (2)
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  • 1
    ISSN: 1435-0661
    Keywords: MBC, microbial biomass carbon MEP, Mehlich extractable phosphorus MLRA, Major Land Resource Areas MWD, mean-weight diameter NRCS, Natural Resources Conservation Service NRI, National Resource Inventory PMN, potentially mineralizable nitrogen PSU, primary sampling units TOC, total organic carbon WSA, water stable aggregates
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: e transformation resulted in normal distributions for most soil properties and reduced variability two- to threefold. However, a few soil properties remained non-normally distributed. Soil pH may be monitored at the regional scale with a high degree of precision. Small changes in soil C content (3–8% of the regional mean) may be detected using loge transformed total organic C as the indicator. Sampling soil properties as part of the NRI should improve NRCS' ability to monitor soil condition on a regional scale.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular neurobiology 20 (2000), S. 497-508 
    ISSN: 1573-6830
    Keywords: tau ; phosphorylation ; signal transduction ; protein kinase C ; Alzheimer's disease
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract 1. The potential functions of the microtubule-associated protein tau have been expanded by the recent demonstration of its interaction with the plasma membrane. Since the association of tau with microtubules is regulated by phosphorylation, herein we examine whether or not the association of tau with the plasma membrane is also regulated by phosphorylation. 2. A range of tau isoforms migrating from 46 to 64 kDa was associated with crude particulate fractions derived from SH-SY-5Y human neuroblastoma cells, and were retained during the initial stages of plasma membrane purification. During the extensive washing utilized in purification of the plasma membrane, portions of each of these isoforms were depleted from the resultant purified membrane. Immunoblot analysis with phospho-dependent and -independent antibodies revealed selective depletion of phospho isoforms during membrane washing. This effect was more pronounced for the slowest-migrating (64-kDa) tau isoform. 3. This putative influence of phosphorylation on the association of tau with the plasma membrane was further probed by transfection of SH-SY-5Y human neuroblastoma cells with a tau construct that could associate with the plasma membrane but not with microtubules. Treatment with phorbol ester or calcium ionophore, both of which increased phospho-tau levels within the cytosol and plasma membrane, was accompanied by the dissociation of this tau construct from the membrane. 4. These data indicate that phosphorylation regulates the association with the plasma membrane. Dissociation from the membrane by phosphorylation may place tau at risk for hyperphosphorylation and ultimate PHF formation in a manner previously considered for tau dissociated from microtubules.
    Type of Medium: Electronic Resource
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