Electronic Resource
Springer
Journal of molecular evolution
23 (1986), S. 189-199
ISSN:
1432-1432
Keywords:
Repetitive DNA
;
Multigene family
;
Alu sequences
;
Retroposons
;
Selfish DNA
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Summary I have analyzed a collection of published human Alu sequences. The compiled sequences show several unexpected features, including a uniform pattern of divergence from their consensus sequence, a mutual divergence that is not correlated with their age, and common features in the genomic DNA flanking the 5′ ends of the elements. I suggest that the Alu family of sequences derives from a large pool of precursors and not from a single precursor similar to the family consensus sequence, and that new elements integrate into the genome selectively at oligo-A-rich sites.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02115575
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