ISSN:
0947-3440
Keywords:
Alkaloids
;
Morphinans
;
Oxadiazolines
;
Thiadiazolines
;
(Thio)Semicarbazones, acetylation of
;
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Treatment of dihydrocodeinone (thio)semicarbazones 1a-d with Ac2O/ZnCl2 afforded (6S)-spiro[morphinan-6,2′(3′H)-[1,3,4]oxadiazolines] (2a, b) and (6R)-spiro[morphinan-6,2′-(3′H)-[1,3,4]thiadiazolines] (3a, b), respectively. The structure of the products including the configuration of the spiro carbons was determined by 1H- and 13C-NMR measurements.
Additional Material:
3 Tab.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jlac.1995199507188
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