Publication Date:
1981-09-25
Description:
Monkeys and human subjects were exposed to a series of thermal stimuli before and after a 53 degrees C, 30-second burn to the glabrous skin of the hand. The responses of C- and A-fiber nociceptive afferents in the monkeys and subjective responses by the humans were compared. The burn resulted in increased sensitivity of the A fibers, decreased sensitivity of the C fibers, and increased pain sensibility (hyperalgesia) in the human subjects.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Meyer, R A -- Campbell, J N -- NS-00519/NS/NINDS NIH HHS/ -- NS-14447/NS/NINDS NIH HHS/ -- New York, N.Y. -- Science. 1981 Sep 25;213(4515):1527-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7280675" target="_blank"〉PubMed〈/a〉
Keywords:
Afferent Pathways/physiology
;
Animals
;
Burns/*physiopathology
;
Hand/innervation
;
Humans
;
Hyperalgesia/*physiopathology
;
Hyperesthesia/*physiopathology
;
Macaca
;
Nerve Fibers/physiology
;
Nerve Fibers, Myelinated/*physiology
;
Nociceptors/*physiology
;
Pain/*physiopathology
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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