Publication Date:
2003-12-13
Description:
The complete genome sequence of Geobacter sulfurreducens, a delta-proteobacterium, reveals unsuspected capabilities, including evidence of aerobic metabolism, one-carbon and complex carbon metabolism, motility, and chemotactic behavior. These characteristics, coupled with the possession of many two-component sensors and many c-type cytochromes, reveal an ability to create alternative, redundant, electron transport networks and offer insights into the process of metal ion reduction in subsurface environments. As well as playing roles in the global cycling of metals and carbon, this organism clearly has the potential for use in bioremediation of radioactive metals and in the generation of electricity.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Methe, B A -- Nelson, K E -- Eisen, J A -- Paulsen, I T -- Nelson, W -- Heidelberg, J F -- Wu, D -- Wu, M -- Ward, N -- Beanan, M J -- Dodson, R J -- Madupu, R -- Brinkac, L M -- Daugherty, S C -- DeBoy, R T -- Durkin, A S -- Gwinn, M -- Kolonay, J F -- Sullivan, S A -- Haft, D H -- Selengut, J -- Davidsen, T M -- Zafar, N -- White, O -- Tran, B -- Romero, C -- Forberger, H A -- Weidman, J -- Khouri, H -- Feldblyum, T V -- Utterback, T R -- Van Aken, S E -- Lovley, D R -- Fraser, C M -- New York, N.Y. -- Science. 2003 Dec 12;302(5652):1967-9.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA. bmethe@tigr.org〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/14671304" target="_blank"〉PubMed〈/a〉
Keywords:
Acetates/metabolism
;
Acetyl Coenzyme A/metabolism
;
Aerobiosis
;
Anaerobiosis
;
Bacterial Proteins/genetics/metabolism
;
Carbon/metabolism
;
Chemotaxis
;
Chromosomes, Bacterial/genetics
;
Cytochromes c/genetics/metabolism
;
Electron Transport
;
Energy Metabolism
;
Genes, Bacterial
;
Genes, Regulator
;
*Genome, Bacterial
;
Geobacter/*genetics/*metabolism/physiology
;
Hydrogen/metabolism
;
Metals/*metabolism
;
Movement
;
Open Reading Frames
;
Oxidation-Reduction
;
Phylogeny
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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