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  • AIRCRAFT DESIGN, TESTING AND PERFORMANCE  (2)
  • 5α-Androstane-3α,17β-diol  (1)
  • 1
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    Unknown
    A family of supersonic airplanes: Technical and economic feasibility (1980)
    In:  Other Sources
    Details
    Publication Date: 2011-08-18
    Description: To improve the prospects for success in the market place, the family approach is essential to the design of future supersonic airplanes. The evolution from a basic supersonic airplane to a family could follow historic patterns, with one exception: substantial changes in passenger carrying capacity will be difficult by the conventional fuselage "doughnut" approach so successfully used on the cylindrical fuselage of subsonic airplanes. The primary reasons for this difference include the requirement for highly integrated "area ruled" configurations, to give the desired high supersonic aerodynamic efficiency, and other physical limitations such as takeoff and landing rotation. A concept for a supersonic airplane family that could effectively solve the variable range and passenger capacity problem provides for modification of the fuselage cross section that makes it possible to build a family of three airplanes with four, five, and six abreast passenger seating. This is done by replacing or modifying portions of the fuselage. All airplanes share the same wing, engines, and major subsystems. Only small sections of the fuselage would be different, and aerodynamic efficiency need not be compromised.
    Keywords: AIRCRAFT DESIGN, TESTING AND PERFORMANCE
    Type: NASA. Langley Research Center Supersonic Cruise Res., 1979, Pt. 2; p 833-854
    Format: text
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    NASA TECHNICAL REPORTS
  • 2
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    Unknown
    Toward a second generation fuel efficient supersonic cruise aircraft (1976)
    In:  CASI
    Details
    Publication Date: 2016-06-07
    Description: Design changes that lead to improved aerodynamic and structural efficiency are presented. Practical design constraints and approaches for a blended wing-fuselage are discussed, as well as the integration of the configuration that leads to aerodynamic and structural efficiency. Highlighted are new approaches used to provide for structural efficiency, airline/passenger acceptance, passenger evacuation, and subsystem integration. Results of full-scale passenger cabin mock-up evaluations are presented showing the feasibility of the concept.
    Keywords: AIRCRAFT DESIGN, TESTING AND PERFORMANCE
    Type: NASA. Langley Res. Center Proc. of the SCAR Conf., Pt. 2,; 18 p
    Format: application/pdf
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    NASA TECHNICAL REPORTS
  • 3
    Electronic Resource
    Electronic Resource
    Role of the pituitary gland in experimental hormonal induction and prevention of benign prostatic hyperplasia in the dog (1979)
    Springer
    Cell & tissue research 204 (1979), S. 367-378 
    Details
    ISSN: 1432-0878
    Keywords: Cyproterone acetate ; 17β-Oestradiol ; 5α-Androstane-3α,17β-diol ; Prostate gland ; Pituitary gland ; Immunocytochemistry ; Dog (beagle)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The antiandrogen, cyproterone acetate (CPA), prevents development of prostatic hyperplasia, induced in castrated dogs by a 6 month-treatment with 5α-androstane-3α,l 7β-diol (A)alone or in combination with 17β-oestradiol (E 2). The immunoperoxidase technique was used to study functional cell types in the pars distalis of the pituitary gland and to detect growth hormone (GH) and prolactin (PRL) target sites in the prostate gland. Homologous radioimmunoassays for estimation of serum canine GH and PRL concentrations were also performed. Treatment with the combinations A + E 2 and A + E 2 + CPA resulted in morphological indications of stimulated GH and PRL cells and depressed gonadotrophs. This correlates well with an increase in PRL-dependent staining in glandular epithelium and fibromuscular tissue of the prostate gland. However, basal serum PRL and GH levels were not significantly affected. Treatment with A and A + E2 stimulated, while additional treatment with CPA clearly suppressed adrenocorticotrophin/melanotrophin (ACTH/MSH) cells. These findings indicate that an endocrine imbalance in hypothalamic-pituitary-adrenal function may be involved in induction and prevention of prostatic hyperplasia in the dog.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00233649
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