ISSN:
0749-1581
Keywords:
1H NMR
;
13C NMR
;
31P NMR
;
1,2-Dipalmitoyl-sn-glycero-3-phosphorylcholine
;
Bilayers
;
Radiation damage
;
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Multilayer membranes of 1,2-dipalmitoyl-sn-glycero-3-phosphorylcholine were prepared in D2O and exposed to γ-radiation. Changes in the chemical structure due to irradiation were studied by 1H, 13C and 31P NMR after lyophilization and dissolution in chloroform-methanol (1 : 2, v/v). One- and two-dimensional techniques were used. 1-Palmitoyl-sn-glycero-3-phosphorylcholine, 2-palmitoyl-sn-glycero-3-phosphorylcholine, glycero-3-phosphorylcholine and palmitic acid were identified as new components. Their development during irradiation was quantitatively determined. The results were discussed in terms of possible reaction steps responsible for the radiolytic decomposition.
Additional Material:
2 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/mrc.1260300510
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