ISSN:
0899-0042
Keywords:
chiral stationary phase
;
3,5-dinitrobenzoyl group
;
chiral recognition mechanism
;
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
(R,S)-N-Acetyl-leucine-2-naphthylamide can be resolved into its enantiomers on a (S)-DNBLeucine chiral stationary phase. The mechanism of this separation was investigated using as model complexes the 1:1 S,S- and the 1:1 R,S-cocrystals of the above naphthylamide and N-3,5-dinitrobenzoylleucinemethylamide, a soluble analogue of the stationary phase. The observed enantiomeric elution order can be rationalized from their X-ray data.
Additional Material:
3 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/chir.530020310
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