ISSN:
0749-1581
Keywords:
2D NMR
;
Phase-sensitive DQF-COSY and ROESY
;
Heteronuclear 13C-1H long-range correlation
;
Steroid alkaloid
;
Germine esters
;
Anti-hypertension
;
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The application of two-dimensional phase-sensitive COSY, ROESY and 13C-1H shift correlation spectroscopy in the structural elucidation and stereochemical assignment of the steroidal alkaloids 15-(2-methylbutyryl)germine, 3-(2-hydroxy-2-methylbutyryl)-15-(2-methylbutyryl)germine and 16-(2-methylbutyryl)germine is reported. It is shown that two-dimensional 13C-1H heteronuclear long-range correlation spectroscopy is an invaluable method for the stereochemical assignment of proton resonances which overlap in 1H NMR and homonuclear correlation spectra.
Additional Material:
4 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/mrc.1260290203
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