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  • 1
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Liebigs Annalen 1993 (1993), S. 451-455 
    ISSN: 0170-2041
    Keywords: Anthracyclinones ; Diels-Alder reactions, asymmetric ; 1,4-Anthraquinone ; Isoprenyl ethers ; 1-Phenylethanol ; Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Diastereoselective Synthesis of Anthracyclinone Precursors[4 + 2] Cycloaddition of various dienes such as 1-acetoxy-1,3-butadienes 4a, b or 1-phenylethyloxy-1,3-butadienes 4c-g with 1,4-anthraquinones 3 affords tetracyclic precursors of anthracyclinone. Using the chiral substituted 1,3-butadienes 4 cycloadducts with d.e. 〉 98% are obtained. The high stereoselectivity is explained by π stacking.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
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