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  • 04. Solid Earth::04.08. Volcanology::04.08.05. Volcanic rocks  (16)
  • 04. Solid Earth::04.08. Volcanology::04.08.08. Volcanic risk  (6)
  • Chemistry  (4)
  • 1
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Helvetica Chimica Acta 12 (1929), S. 989-990 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 2 Ill.
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  • 2
    ISSN: 0899-0042
    Keywords: albendazole ; enantiomeric separation ; high performance liquid chromatography ; cellulose derived phase ; pharmacokinetic ; cysticercosis ; Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: We present a method for the enantioselective analysis of albendazole sulfoxide (ABZSO) in plasma for application in clinical pharmacokinetic studies. ABZSO enantiomers were separated on a 5-μm Chiralcel OB-H® column (4.6 × 150 mm) using hexane:ethanol (93:7, v/v) as the mobile phase and fluorescence detection. ABZSO was extracted with chloroform:isopropanol (8:2, v/v) from 500-μl aliquots of acidified plasma, with full drug recovery. The proposed method presented quantitation limits of 20 ng/ml for (-)ABZSO and 50 ng/ml for (+)ABZSO and was linear up to a concentration of 5,000 ng/ml of each enantiomer. Chirality 9:722-726, 1997. © 1997 Wiley-Liss, Inc.
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  • 3
    ISSN: 0899-0042
    Keywords: optical resolution ; chiral HPLC ; chiral stationary phase ; 6-oxazolinylisoflavan ; circular dichroism ; antipicornavirus activity ; Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Racemic 6-oxazolinylisoflavan, a highly effective inhibitor of rhinovirus serotype 1B in vitro, was resolved by high-performance liquid chromatography on a chiral stationary phase in order to study the activity of the enantiomers against picornaviruses. The absolute configuration of the two isomers was determined by circular dichroism curves. The antipicornavirus activity of each isomer, separately collected, was evaluated in vitro against human rhinovirus serotype 1B, enterovirus 71, echovirus 6, coxsackievirus B4, and poliovirus type 2 by means of the plaque reduction assay. Both enantiomers were inhibitors of picornavirus replication with the degree of their activity depending on virus and isomer tested. © 1993 Wiley-Liss, Inc.
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  • 4
    ISSN: 0173-0835
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: In cystic fibrosis (CF), the most common mutation, delta F508 (a three-base-pair deletion) accounts for ca. 70% of mutations in the worldwide population. The majority of other mutations (more than 350 reported so far to the Genetic Analysis Consortium) have been detected in single cases, thus rendering quite cumbersome a molecular diagnostic approach for the identification of CF chromosomes. As an alternative, linkage analysis based on intragenic polymorphism can be useful for prenatal diagnosis and CF-carrier detection, provided that the heterozygosity of the allelic forms is very high. For this purpose, DNA microsatellites, consisting of two to epta nucleotide repeat clusters, displaying a high degree of polymorphism, are being increasingly used as markers in linkage studies. Two main allelic forms, one hexameric (111 bp) and one heptameric (115 bp), of a tetranucleotide (GATT) repeat polymorphism, at the junction of intron IVS6a and exon 6b, have been amplified by PCR technology. These two alleles can be separated in a 10-20%T polyacrylamide gradient gel and detected by ethidium bromide staining. As an alternate procedure, these two fragments are efficiently separated by capillary zone electrophoresis in a viscous solution of 6%T linear polyacrylamide and detected by their intrinsic absorbance at 254 nm.
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  • 5
    Publication Date: 2020-11-17
    Description: Volcanic activity on the island of Ischia included both effusive and explosive eruptions, mainly occurred in the eastern sector of the island. Vent location, eruption dynamics, transport mechanisms and depositional processes, have been reconstructed for each recognized unit. In the past 10 ka, periods of quiescence alternated with periods of very intense volcanism, which was mainly concentrated at about 5.5 and over the past 2.9 ka. Volcanism was not continuous and strongly influenced by the mechanism of a resurgence phenomenon, which affects the island since about 33 ka. Therefore, it has been hypothesized that magma intrusion and uplift events occurred intermittently. In the past 5.5 ka, volcanic activity has been invariably accompanied by the emplacement of slope instability-related deposits testifying that also slope instability was induced by reactivation of vertical movements, likely related to resurgence.
    Description: Published
    Description: 193-239
    Description: 6V. Pericolosità vulcanica e contributi alla stima del rischio
    Description: reserved
    Keywords: Volcanological ; Ischia resurgent ; 04. Solid Earth::04.08. Volcanology::04.08.05. Volcanic rocks ; 04. Solid Earth::04.08. Volcanology::04.08.08. Volcanic risk ; 05. General::05.02. Data dissemination::05.02.03. Volcanic eruptions
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: book chapter
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  • 6
    Publication Date: 2020-12-17
    Description: The Neapolitan Yellow Tuff (NYT) is the product of the largest known trachytic phreatoplinian eruption. It covered an area larger than 1000 km2 with an estimated volume of about 40 km3 of erupted magma. During the course of the eruption a caldera collapsed within the previously formed Campanian Ignimbrite caldera. The resulting nested structure strongly influenced the following volcanic activity in the Campi Flegrei caldera. As previous dating of the NYT does not converge toward a unique result, a new set of 40Ar/39Ar age determinations has been carried out to better constrain the age of the eruption. Two variants of the 40Ar/39Ar dating method were applied to determine the age of the NYT eruption: (1) single-crystal total fusion (SCTF), on an individual phenocryst of feldspar, and (2) laser incremental heating (LIH), on bulk aliquots of feldspar phenocrysts. The results of the SCTF analyses show that the overall sample weighted mean age, derived from the conventional age calculation, is 15.6 ;0.8 ka. A weighted mean of the isochron age is 15.3 ;1.2 ka (2c), and has been assumed as the best indicator of age to be derived from the SCTF analyses. The LIH analyses results show that plateau ages vary from 15.4; 0.5 to 14.5; 0.5 ka. The overall weighted mean age of the isochron results is 14.9;0.4 ka (2c). This result has been assumed as the reference age for the NYT eruption, and agrees with the SCTF age. The new age obtained for the NYT deposits is of great relevance for the understanding of the evolution and the present state of the Campi Flegrei caldera and collocates the NYT in a crucial stratigraphical position to date the climatic oscillations that occurred between the Late Glacial and the Holocene.
    Description: Published
    Description: 157-170
    Description: partially_open
    Keywords: Neapolitan Yellow Tuff ; Campi Flegrei caldera ; 40Ar/39Ar dating method ; Geochronology ; Late Glacial ; Holocene ; 04. Solid Earth::04.04. Geology::04.04.02. Geochronology ; 04. Solid Earth::04.04. Geology::04.04.10. Stratigraphy ; 04. Solid Earth::04.08. Volcanology::04.08.05. Volcanic rocks ; 05. General::05.02. Data dissemination::05.02.03. Volcanic eruptions
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
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  • 7
    Publication Date: 2017-04-04
    Description: In order to improve the microscopic understanding of the water-magma interaction process during explosive volcanism,volcanic glasses representative of deposits with sedimentological characteristics suggesting different water/melt ratios were studied by a combination of the nuclear magnetic resonance (NMR) and TIMS methods. The glasses were separated from pumices of two surge layers and one fallout bed of the Cretaio Tephra (Ischia Island,Italy), which is the product of an explosive eruption that occurred at Ischia in the second century BC. The 29Si CP^MAS NMR experiments indicate the occurrence of 1H^29Si dipolar couplings in glasses from the phreatomagmatic activity, suggesting the presence of hydrogen atoms in proximity of silicon atoms. This feature is not detected in the glass from the deposit of the magmatic explosion. 1H MAS NMR spectra reveal different peaks attributed to different hydrous species characterized by different motional properties. These include ‘rigid’ H2O groups isolated in the glass structure, more mobile water species and possibly structural hydroxyl groups. 1H MAS NMR spectra recorded after deuteration experiments of the glass at a temperature up to 300‡C revealed that the exchange reactions of the D2O vapor with hydrogen were limited to the most mobile water species,possibly on vesicle surfaces or in channels. The hydrogen concentration linearly correlates with the 87Sr/86Sr isotope ratio in glasses,suggesting isotopic tracer exchanges between the Sr dissolved in the water vapor and the Sr in the silicon-oxygen network during hydration. It is proposed that the uprising melt interacted with a hydrothermal system of seawater-derived fluids,characterized by relatively high Sr isotopic composition.
    Description: Published
    Description: 311-320
    Description: partially_open
    Keywords: Ischia ; Cretaio Tephra ; Water-melt interaction ; Nuclear magnetic resonance ; Sr isotopes ; 04. Solid Earth::04.08. Volcanology::04.08.05. Volcanic rocks ; 04. Solid Earth::04.08. Volcanology::04.08.07. Instruments and techniques
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
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  • 8
    Publication Date: 2017-04-04
    Description: The structure and shape of collapses and resurgences is often controlled by pre-existing discontinuities, such as normal faults in rift zones. In order to study the role of extensional structures on collapse and resurgence, we used analogue models. Dry sand simulated the brittle crust; silicone, located at the base of the sand-pack, simulated magma. In the experiments, regional extension pre-dated collapse or resurgence, forming normal faults in a grabenlike structure; the graben was filled with additional sand, simulating post-rift deposits. A piston then moved the silicone downward or upward, inducing collapse or resurgence within the previously deformed sand. The collapses showed an ellipticity (length of minor axis/length of major axis) between 0.8 and 0.9, with the major axis parallel to the extension direction. The partial reactivation of the pre-existing normal faults was observed during the development of the caldera reverse faults, which, conversely to what was expected (from experiments without preexisting extension), became partly inward dipping. Resurgence showed an elongation of the uplifted part, with the main axis perpendicular to the extension direction. At depth, pre-existing normal faults were partly reactivated by the reverse faults formed during resurgence; these locally became outward dipping normal faults. A total reactivation of pre-existing faults was also observed during resurgence. The experiments suggest that the observed elongation of calderas and resurgences is the result of the reactivation of pre-existing structures during differential uplift. Such a reactivation is mainly related to the loss in the coefficient of friction of the sand. The results suggest that elliptic calderas and resurgences in nature may develop even from circular magma chambers.
    Description: Published
    Description: 199-217
    Description: partially_open
    Keywords: Extensional structures ; Caldera ; Resurgence ; Analogue models ; Reactivation ; 04. Solid Earth::04.08. Volcanology::04.08.08. Volcanic risk
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
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  • 9
    Publication Date: 2017-04-04
    Description: The Agnano^Monte Spina Tephra (AMST) is a complex sequence of beds generated by contrasting fragmentation and transportation dynamics. The 4.1 ka eruption was accompanied by a volcano-tectonic collapse, part of which is the present Agnano plain. The pyroclastic sequence is subdivided into members and submembers, each characterized by different lithological and sedimentological features. Plinian/subplinian fallout deposits frequently alternate with base-surge beds of phreatomagmatic origin. Analysis of lateral facies variations and vertical facies associations of correlated layers of submembers B2, D2 and E2 reveals that during some eruption phases the contrasting eruptive dynamics were almost contemporaneous. Base-surge deposits of submember B2 formed during the declining stage of a plinian column. They resulted from highly energetic and steady pyroclastic density currents that traveled long distances from the vent area and surmounted topographic obstacles such as the Posillipo hill (V150 m) and the northern sector of the Camaldoli hill (V250 m). Submember D2 pyroclastic density currents formed when contemporaneous fallout from an eruptive column was present. Coarse particles from the column settled throughout the pyroclastic density current, determining a significant increase of the solid load of the base surge. The consequent increase of supply rate from the transportation to the depositional zone of the base surge led to the formation of unsteady flows that could not efficiently transport the solid load and did not have the ability to travel long distances. Base-surge deposits of submember E2 were fed by a pulsating phreatomagmatic activity, which was punctuated by a short-lived fallout phase. Fallout material, which was incorporated as an additional load to the base surges, was partially transported by low-energy, steady pyroclastic density currents that traveled over the Agnano plain but did not surmount either the Camaldoli or the Posillipo hills. Only the very fine material, in continuous suspension in the upper, no-shearing part of the base-surge cloud, was dispersed higher in the atmosphere and quietly settled over a large area outside the caldera rim. The phreatomagmatic origin of base surges, which contrasts with the magmatic origin of fallout activity, suggests that the pyroclastic density currents of the Agnano^Monte Spina eruption did not result from eruption column collapses. They were most likely related to radially spreading clouds which were contemporaneous with fallout activity but issued from distinct zones in the vent area. The turbulent nature and the high expansion of base surges made them capable, under certain conditions, of passing over high topographic obstacles, with hazardous effects in distal areas.
    Description: Published
    Description: 193-210
    Description: partially_open
    Keywords: base-surge deposits ; Campi Flegrei ; phreatomagmatism ; fallout deposits ; 04. Solid Earth::04.04. Geology::04.04.08. Sediments: dating, processes, transport ; 04. Solid Earth::04.08. Volcanology::04.08.05. Volcanic rocks
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
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  • 10
    Publication Date: 2017-04-04
    Description: Eruption forecasting and hazard assessments at the restless Campi Flegrei caldera, within the Neapolitan volcanic area, have been performed using stratigraphical, volcanological, structural and petrological data. On the basis of the reconstructed variation of eruption magnitude through time, we hypothesize that the most probable maximum expected event is a medium-magnitude explosive eruption, fed by trachytic magma. Such an eruption could likely occur in the north-eastern sector of the caldera floor that is under a tensile stress regime, when the ongoing deformation will generate mechanical failure of the rocks. A vent could open also in the western sector, at the intersection of two fault systems contemporaneously activated, as happened in the last eruption at Monte Nuovo. The eruption could likely be preceded by precursors apparent to the population, such as ground deformation, seismicity and increase in gas emissions. It will probably alternate between magmatic and phreatomagmatic phases with the generation of tephra fallout, and dilute and turbulent pyroclastic currents. During and/or after the eruption, the re-mobilization of ash by likely heavy rains, could probably generate mud flows. In order to perform a zoning of the territory in relation to the expected volcanic hazards, we have constructed a comprehensive hazard map. On this map are delimited (I) areas of variable probability of opening of a new vent, (II) areas which could be affected by variable load of fallout deposits, and (III) areas over which pyroclastic currents could flow. The areas in which a vent could likely open have been defined on the basis of the dynamics of the ongoing deformation of the caldera floor. To construct the fallout hazard map we have used the frequency of deposition of fallout beds thicker than 10 cm, the frequency of load on the ground by tephra fallout and the direction of dispersal axes of the deposits of the last 5 ka, and the limit load of collapse for the variable types of roof construction. The pyroclastic-current hazard map is based on the areal distribution and frequency of pyroclastic-current deposits of the last 5 ka.
    Description: Published
    Description: 514-530
    Description: partially_open
    Keywords: Volcanic hazard ; Campi Flegrei ; 04. Solid Earth::04.04. Geology::04.04.08. Sediments: dating, processes, transport ; 04. Solid Earth::04.04. Geology::04.04.10. Stratigraphy ; 04. Solid Earth::04.08. Volcanology::04.08.05. Volcanic rocks
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