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  • 1
    Electronic Resource
    Electronic Resource
    Effects of cooling and equilibration in DMSO, and cryopreservation of mouse oocytes, on the rates of in vitro fertilization, development, and chromosomal abnormalities (1995)
    New York, NY [u.a.] : Wiley-Blackwell
    Molecular Reproduction and Development 40 (1995), S. 110-115 
    Details
    ISSN: 1040-452X
    Keywords: Aneuploidy ; Cryoprotectant ; Fertility ; Polyploidy ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Notes: In a previous study, we have shown that the cryopreservation of mouse oocytes caused increases in the rates of degeneration and of digynic polyploid embryos, while the fertility of frozen-thawed oocytes was decreased. In this study, we have attempted to determine the different stages in the complete freezing-thawing process which are deleterious for the oocytes and the subsequent zygotes. IVF assays showed that DMSO decreased the fertility of oocytes, whereas cooling to 0°C had no effect. DMSO, used at 0°C, was less deleterious for oocytes. Thus, the prefreezing manipulations seem to be important for the quality and fertility of oocytes. However, neither DMSO nor cooling increased the incidence of chromosomal abnormalities in embryos obtained from inseminated exposed oocytes. Therefore, the increased frequency of polyploidy observed in embryos after the cryopreservation of mouse oocytes must correspond to disruption occurring during the freezing-thawing process.
    Additional Material: 2 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/mrd.1080400114
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    Paper (German National Licenses)
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  • 2
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    Forecasting the effects of the Andaman Islands - Sumatra megathrust earthquakes (Dec. 2004 and Mar. 2005) on volcanoes in the surrounding area (2006)
    Details
    Publication Date: 2017-04-04
    Description: The Andaman Islands - Sumatra earthquake (Mw = 9.3, Dec. 2004) and the subsequent Sumatra earthquake (Mw = 8.7, Mar. 2005) represent one of most energetic sequence of earthquakes ever recorded. Since both events occurred in a strongly active volcanic region, their exceptionally strong stress perturbation gives the opportunity to understand the effects of stress perturbations on volcanic systems. Here, we set the rules for a forward test of the causal relationship between stress perturbation and subsequent volcanic eruptions, by means of the comparison of the spatio-temporal distribution of the eruptions which follow the earthquakes with the co- and the post-seismic stress field due to the earthquakes. In practice, we forecast that the volcanic activity of the next 30 years will be significantly promoted by the stress perturbation; thus, we define the rules for an objective test of such an hypothesis. Given the extremely high values of stress perturbation due to this sequence of earthquakes, the results of our test will definitively provide a reliable evaluation of the possible statistical impact of earthquake-eruption interaction on long-term volcanic hazard assessments.
    Description: Unpublished
    Description: open
    Keywords: Earthquake-volcano interaction, stastical model, stress field, ; stress field ; Statistical model ; 04. Solid Earth::04.06. Seismology::04.06.02. Earthquake interactions and probability ; 04. Solid Earth::04.06. Seismology::04.06.08. Volcano seismology ; 05. General::05.01. Computational geophysics::05.01.04. Statistical analysis
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: manuscript
    Format: 724315 bytes
    Format: application/pdf
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  • 3
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    Probabilistic short-term volcanic hazard in phases of unrest: A case study for tephra fallout (2015)
    Wiley
    Details
    Publication Date: 2017-04-04
    Description: During volcanic crises, volcanologists estimate the impact of possible imminent eruptions usually through deterministic modeling of the effects of one or a few preestablished scenarios. Despite such an approach may bring an important information to the decision makers, the sole use of deterministic scenarios does not allow scientists to properly take into consideration all uncertainties, and it cannot be used to assess quantitatively the risk because the latter unavoidably requires a probabilistic approach. We present a model based on the concept of Bayesian event tree (hereinafter named BET_VH_ST, standing for Bayesian event tree for short-term volcanic hazard), for short-term near-real-time probabilistic volcanic hazard analysis formulated for any potential hazardous phenomenon accompanying an eruption. The specific goal of BET_VH_ST is to produce a quantitative assessment of the probability of exceedance of any potential level of intensity for a given volcanic hazard due to eruptions within restricted time windows (hours to days) in any area surrounding the volcano, accounting for all natural and epistemic uncertainties. BET_VH_ST properly assesses the conditional probability at each level of the event tree accounting for any relevant information derived from the monitoring system, theoretical models, and the past history of the volcano, propagating any relevant epistemic uncertainty underlying these assessments. As an application example of the model, we apply BET_VH_ST to assess short-term volcanic hazard related to tephra loading during Major Emergency Simulation Exercise, a major exercise at Mount Vesuvius that took place from 19 to 23 October 2006, consisting in a blind simulation of Vesuvius reactivation, from the early warning phase up to the final eruption, including the evacuation of a sample of about 2000 people from the area at risk. The results show that BET_VH_ST is able to produce short-term forecasts of the impact of tephra fall during a rapidly evolving crisis, accurately accounting for and propagating all uncertainties and enabling rational decision making under uncertainty.
    Description: Published
    Description: 8805–8826
    Description: 3V. Dinamiche e scenari eruttivi
    Description: JCR Journal
    Description: embargoed_20161231
    Keywords: short-term probabilistic volcanic hazard analysis ; bayesian event tree ; 05. General::05.01. Computational geophysics::05.01.04. Statistical analysis
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
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  • 4
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    BET_VH: exploring the influence of natural uncertainties on long-term hazard from tephra fallout at Campi Flegrei (Italy) (2010)
    Springer Berlin / Heidelberg
    Details
    Publication Date: 2017-04-04
    Description: In this paper, we explore the effects of the intrinsic uncertainties upon long-term volcanic hazard by analyzing tephra fall hazard at Campi Flegrei, Italy, using the BET_VH model described in Marzocchi et al. (Bull Volcanol, 2010). The results obtained show that volcanic hazard based on the weighted average of all possible eruptive settings (i.e. size classes and vent locations) is significantly different from an analysis based on a single reference setting, as commonly used in volcanic hazard practice. The long-term hazard map for tephra fall at Campi Flegrei obtained here accounts for a wide spectrum of uncertainties which are usually neglected, largely reducing the bias intrinsically introduced by the choice of a specific reference setting. We formally develop and apply a general method to recursively integrate simulations from different models which have different characteristics in terms of spatial coverage, resolution and physical details. This outcome of simulations will be eventually merged with field data through the use of the BET_VH model.
    Description: Published
    Description: 717-733
    Description: 4.3. TTC - Scenari di pericolosità vulcanica
    Description: JCR Journal
    Description: open
    Keywords: Volcanic hazard ; Ash fall · ; Bayesian event tree ; Campi Flegrei ; 04. Solid Earth::04.08. Volcanology::04.08.08. Volcanic risk ; 05. General::05.01. Computational geophysics::05.01.04. Statistical analysis
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
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  • 5
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    Probabilistic hazard for seismically induced tsunamis: accuracy and feasibility of inundation maps (2015)
    Wiley-Blackwell
    Details
    Publication Date: 2017-04-04
    Description: Probabilistic tsunami hazard analysis (PTHA) relies on computationally demanding numerical simulations of tsunami generation, propagation, and non-linear inundation on high-resolution topo-bathymetric models. Here we focus on tsunamis generated by co-seismic sea floor dis- placement, that is, on Seismic PTHA (SPTHA). A very large number of tsunami simulations are typically needed to incorporate in SPTHA the full expected variability of seismic sources (the aleatory uncertainty). We propose an approach for reducing their number. To this end, we (i) introduce a simplified event tree to achieve an effective and consistent exploration of the seismic source parameter space; (ii) use the computationally inexpensive linear approximation for tsunami propagation to construct a preliminary SPTHA that calculates the probability of maximum offshore tsunami wave height (H Max) at a given target site; (iii) apply a two-stage filtering procedure to these ‘linear’ SPTHA results, for selecting a reduced set of sources and (iv) calculate ‘non-linear’ probabilistic inundation maps at the target site, using only the selected sources. We find that the selection of the important sources needed for approximating probabilistic inundation maps can be obtained based on the offshore HMax values only. The filtering procedure is semi-automatic and can be easily repeated for any target sites. We describe and test the performances of our approach with a case study in the Mediterranean that considers potential subduction earthquakes on a section of the Hellenic Arc, three target sites on the coast of eastern Sicily and one site on the coast of southern Crete. The comparison between the filtered SPTHA results and those obtained for the full set of sources indicates that our approach allows for a 75–80 per cent reduction of the number of the numerical simulations needed, while preserving the accuracy of probabilistic inundation maps to a reasonable degree.
    Description: Published
    Description: 574-588
    Description: 3T. Pericolosità sismica e contributo alla definizione del rischio
    Description: JCR Journal
    Description: restricted
    Keywords: Tsunami ; Hazard ; Probabilistic ; Subduction ; Mediterranean ; SPTHA ; 04. Solid Earth::04.06. Seismology::04.06.02. Earthquake interactions and probability ; 04. Solid Earth::04.07. Tectonophysics::04.07.04. Plate boundaries, motion, and tectonics ; 04. Solid Earth::04.07. Tectonophysics::04.07.06. Subduction related processes
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
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  • 6
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    Integrating geologic fault data into tsunami hazard studies (2013)
    Copernicus Publications
    Details
    Publication Date: 2017-04-04
    Description: We present the realization of a fault-source data set designed to become the starting point in regional-scale tsunami hazard studies. Our approach focuses on the parametric fault characterization in terms of geometry, kinematics, and assessment of activity rates, and includes a systematic classification in six justification levels of epistemic uncertainty related with the existence and behaviour of fault sources. We set up a case study in the central Mediterranean Sea, an area at the intersection of the European, African, and Aegean plates, characterized by a complex and debated tectonic structure and where several tsunamis occurred in the past. Using tsunami scenarios of maximum wave height due to crustal earthquakes (Mw=7) and subduction earthquakes (Mw=7 and Mw=8), we illustrate first-order consequences of critical choices in addressing the seismogenic and tsunamigenic potentials of fault sources. Although tsunamis generated by Mw=8 earthquakes predictably affect the entire basin, the impact of tsunamis generated by Mw=7 earthquakes on either crustal or subduction fault sources can still be strong at many locales. Such scenarios show how the relative location/orientation of faults with respect to target coastlines coupled with bathymetric features suggest avoiding the preselection of fault sources without addressing their possible impact onto hazard analysis results.
    Description: This work was supported by the EC-Research Framework programme FP7, Seismic Hazard Harmonization in Europe, Grant Agreement No. 226769 and the Flagship Project RITMARE – The Italian Research for the Sea – coordinated by the Italian National Research Council and funded by the Italian Ministry of Education, University and Research within the National Research Program 2011–2013.
    Description: Published
    Description: 1025-1050
    Description: 3.2. Tettonica attiva
    Description: 4.2. TTC - Modelli per la stima della pericolosità sismica a scala nazionale
    Description: JCR Journal
    Description: open
    Keywords: active fault ; tsunami ; tsunamigenic source ; earthquake ; PTHA ; hazard ; epistemic uncertainty ; tectonic moment rate ; 03. Hydrosphere::03.01. General::03.01.01. Analytical and numerical modeling ; 04. Solid Earth::04.04. Geology::04.04.01. Earthquake geology and paleoseismology ; 04. Solid Earth::04.04. Geology::04.04.04. Marine geology ; 04. Solid Earth::04.04. Geology::04.04.09. Structural geology ; 04. Solid Earth::04.06. Seismology::04.06.02. Earthquake interactions and probability ; 04. Solid Earth::04.07. Tectonophysics::04.07.04. Plate boundaries, motion, and tectonics ; 04. Solid Earth::04.07. Tectonophysics::04.07.06. Subduction related processes ; 04. Solid Earth::04.07. Tectonophysics::04.07.07. Tectonics
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
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