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  • 1
    Publication Date: 1987-05-29
    Description: The epithelial cell layer of human amnion membrane can be removed while the basement membrane and stromal surfaces remain morphologically intact. Such a preparation has been used as a substratum for the in vitro culture of dissociated neurons. Embryonic motor neurons from chick ciliary ganglion attached to both surfaces but grew extensive neurites only on the basement membrane. On cross sections of rolled amnion membranes, regenerating axons of cultured neurons were guided along pathways of basement membrane that were immunoreactive with an antibody to laminin. In addition, when rolled amnion membranes were implanted into a lesion cavity between the rat septum and hippocampus, cholinergic neurons extended axons through the longitudinally oriented implant into the hippocampus. Thus, this amnion preparation can serve as a bridge to promote axonal regeneration in vivo in damaged adult brain.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Davis, G E -- Blaker, S N -- Engvall, E -- Varon, S -- Manthorpe, M -- Gage, F H -- AM30051/AM/NIADDK NIH HHS/ -- CA28896/CA/NCI NIH HHS/ -- NS16349/NS/NINDS NIH HHS/ -- New York, N.Y. -- Science. 1987 May 29;236(4805):1106-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/3576223" target="_blank"〉PubMed〈/a〉
    Keywords: *Amnion ; Animals ; Axons/*growth & development ; Basement Membrane ; Chick Embryo ; Humans ; In Vitro Techniques ; Motor Neurons/growth & development ; Rats
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 2
    Publication Date: 2022-05-26
    Description: Author Posting. © American Meteorological Society, 2014. This article is posted here by permission of American Meteorological Society for personal use, not for redistribution. The definitive version was published in Journal of Climate 27 (2014): 3596–3618, doi:10.1175/JCLI-D-13-00070.1.
    Description: Estimates of the recent mean and time varying water mass transformation rates associated with North Atlantic surface-forced overturning are presented. The estimates are derived from heat and freshwater surface fluxes and sea surface temperature fields from six atmospheric reanalyses—the Japanese 25-yr Reanalysis (JRA), the NCEP–NCAR reanalysis (NCEP1), the NCEP–U.S. Department of Energy (DOE) reanalysis (NCEP2), the European Centre for Medium-Range Weather Forecasts (ECMWF) Interim Re-Analysis (ERA-I), the Climate Forecast System Reanalysis (CFSR), and the Modern-Era Reanalysis for Research and Applications (MERRA)—together with sea surface salinity fields from two globally gridded datasets (World Ocean Atlas and Met Office EN3 datasets). The resulting 12 estimates of the 1979–2007 mean surface-forced streamfunction all depict a subpolar cell, with maxima north of 45°N, near σ = 27.5 kg m−3, and a subtropical cell between 20° and 40°N, near σ = 26.1 kg m−3. The mean magnitude of the subpolar cell varies between 12 and 18 Sv (1 Sv ≡ 106 m3 s−1), consistent with estimates of the overturning circulation from subsurface observations. Analysis of the thermal and haline components of the surface density fluxes indicates that large differences in the inferred low-latitude circulation are largely a result of the biases in reanalysis net heat flux fields, which range in the global mean from −13 to 19 W m−2. The different estimates of temporal variability in the subpolar cell are well correlated with each other. This suggests that the uncertainty associated with the choice of reanalysis product does not critically limit the ability of the method to infer the variability in the subpolar overturning. In contrast, the different estimates of subtropical variability are poorly correlated with each other, and only a subset of them captures a significant fraction of the variability in independently estimated North Atlantic Subtropical Mode Water volume.
    Description: JPG is funded by UK Natural Environment Research Council New Investigator Grant NE/I001654/1. Y-OK was supported by the U.S. National Science Foundation under Grant OCE-0424492. RJB is supported by a fellowship from the UK National Centre for Earth Observation.
    Description: 2014-11-15
    Keywords: Atmosphere-ocean interaction ; Meridional overturning circulation ; Ocean circulation
    Repository Name: Woods Hole Open Access Server
    Type: Article
    Format: application/pdf
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