micellar electrokinetic chromatography
Analytical Chemistry and Spectroscopy
Wiley InterScience Backfile Collection 1832-2000
Chemistry and Pharmacology
We have utilized micellar electrokinetic chromatography with sodium deoxycholate micelles to separate the enantiomers of bis(8-((pyridine-2-methylene)amino)quinoline)iron(II) hexafluorophosphate, Fe(PMAQ)2(PF6)2, bis(8-((pyridine-2-methylene)amino)lepidine iron(II) hexafluorophosphate, Fe(PMAL)2(PF6)2, and bis(1-(2-pyridinyl)ethylidine)-8-aminoquinoline iron(II) hexafluorophosphate, Fe(PEAQ)2(PF6)2. The influence of 13 water miscible organic additives on the resolution of each pair of enantiomers was investigated. Significant changes in resolution are seen depending upon the particular organic additive used in the separation buffer. In addition, the effects of acetone concentration on the resolution of these enantiomers in bile salt solution was investigated. Resolution for all three pairs of enantiomers is maximized in a buffer solution containing 15% acetone. © 1995 John Wiley & Sons, Inc.
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