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  • 1
    Publication Date: 1981-12-04
    Description: A DNA sequence coding for the immunogenic capsid protein VP3 of foot-and-mouth disease virus A12, prepared from the virion RNA, was ligated to a plasmid designed to express a chimeric protein from the Escherichia coli tryptophan promoter-operator system. When Escherichia coli transformed with this plasmid was grown in tryptophan-depleted media, approximately 17 percent of the total cellular protein was found to be an insoluble and stable chimeric protein. The purified chimeric protein competed equally on a molar basis with VP3 for specific antibodies to foot-and-mouth disease virus. When inoculated into six cattle and two swine, this protein elicited high levels of neutralizing antibody and protection against challenge with foot-and-mouth disease virus.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kleid, D G -- Yansura, D -- Small, B -- Dowbenko, D -- Moore, D M -- Grubman, M J -- McKercher, P D -- Morgan, D O -- Robertson, B H -- Bachrach, H L -- New York, N.Y. -- Science. 1981 Dec 4;214(4525):1125-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6272395" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Animals ; Antibody Formation ; Base Sequence ; Cattle ; Cattle Diseases/*prevention & control ; *Cloning, Molecular ; DNA Restriction Enzymes ; DNA, Recombinant/metabolism ; Foot-and-Mouth Disease/*prevention & control ; Immunity, Cellular ; Protein Biosynthesis ; Swine ; Swine Diseases/*prevention & control ; Transcription, Genetic ; *Vaccines ; Viral Proteins/genetics/*therapeutic use
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 2
    Publication Date: 2011-08-18
    Description: It is pointed out that the redeployment of ISEE 3 from its continuous monitoring of the solar wind in a large orbit about the upstream Lagrangian point to an extended magnetotail orbit has afforded an opportunity for deep-tail passage of October 1982, and in the radial range from 200 to 220 R(E) during the near-apogee part of the second tail passage in January-February 1983. Attention is given to instrumentation and data sets, spacecraft positions, and observational data.
    Keywords: GEOPHYSICS
    Type: Journal of Geophysical Research (ISSN 0148-0227); 89; 3855-386
    Format: text
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  • 3
    Publication Date: 2019-08-13
    Description: Dynamics Explorer 1 measurements of intense low-frequency electric and magnetic noise observed at low altitudes over the auroral zone are described. The intensity of both the electric and magnetic fields decreases rapidly with increasing frequency. Most of the energy is at frequencies below the O(+) cyclotron frequency, and some evidence is found for a cutoff or change in spectral slope near that frequency. The magnetic to electric field ratio decreases rapidly with increasing radial distance and also decreases with increasing frequency. The polarization of the electric field in a plane perpendicular to the earth's magnetic field is essentially random. The transverse electric and magnetic fields are closely correlated, with the average Poynting flux directed toward the earth. The total electromagnetic power flow associated with the noise is substantial. Two general models are discussed to interpret these observations, one based on static electric and magnetic fields imbedded in the ionosphere and the other based on Alfven waves propagating along the auroral field lines.
    Keywords: GEOPHYSICS
    Type: AD-A150627 , Journal of Geophysical Research (ISSN 0148-0227); 89; 8971-898
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  • 4
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1984-03-16
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉O'Brien, S J -- Goldman, D -- Knight, J -- Moore, H D -- Wildt, D E -- Bush, M -- Montali, R J -- Kleiman, D -- New York, N.Y. -- Science. 1984 Mar 16;223(4641):1127-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6701515" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Carnivora ; Male ; *Paternity ; Polymorphism, Genetic ; Proteins/analysis
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 5
    Publication Date: 2013-08-31
    Description: A ground-based search for stratospheric 35-ClO was carried out using an infrared heterodyne spectrometer in the solar absorption mode. Lines due to stratospheric HNO3 and tropospheric OCS were detected at about 0.2% absorptance levels, but the expected 0.1% lines of ClO in this same region were not seen. We find that stratospheric ClO is at least a factor of seven less abundant than is indicated by in situ measurements, and we set an upper limit of 2.3x10 to the 13th molecules/sq cm at the 95% confidence level for the integrated vertical column density of ClO. Our results imply that the release of chlorofluorocarbons may be significantly less important for the destruction of stratospheric ozone (O3) than is currently thought.
    Keywords: GEOPHYSICS
    Type: NASA-TM-85026 , NAS 1.15:85026
    Format: application/pdf
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  • 6
    Publication Date: 2013-08-31
    Description: Contours and gridded values are given for seven years of monthly mean total ozone data derived from observations with the Backscattered Ultraviolet instrument on Nimbus-4 for the Northern and Southern Hemispheres. The instrument, algorithm, uncertainties in derived ozone and systematic changes in the bias with respect to the international groundbased ozone network of Dobson instruments, are discussed.
    Keywords: GEOPHYSICS
    Type: NASA-RP-1098 , REPT-82F0128-VOL-1 , NAS 1.61:1098
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  • 7
    Publication Date: 2013-08-31
    Description: A ground based search for the 856.50137/cm R(9.5) and for the 859.76765 R(12.5) transitions of stratospheric (Cl-35)O was made in the solar absorption mode using an infrared heterodyne spectrometer. Lines due to stratospheric HNO3 and tropospheric OCS were detected, at about 0.3% absorption levels. The expected lines of ClO in this same region were not detected, even though the optical depth of the ClO lines should be on the order of 0.2% using currently accepted ClO abundances. These infrared measurements suggest that stratospheric ClO is at least a factor of 7 less abundant than is indicated by indirect in situ fluorescence measurements, and the upper limit of 2.4x10 to the 13th power molecules/sq cm to the integrated column density of ClO is a factor of over 4 less than is indicted by microwave measurements. Results imply that the release of fluorocarbon precursors of ClO may be significantly less important for the destruction of stratospheric ozone than was previously thought.
    Keywords: GEOPHYSICS
    Type: NASA-TM-83939 , NAS 1.15:83939
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  • 8
    Publication Date: 2013-08-31
    Description: Increased understanding of the chemical phenomena occurring in the troposphere was the research goal. Emphasis was placed on tropospheric impact on environmental quality, including public health, agriculture, climate, and weather.
    Keywords: GEOPHYSICS
    Type: L-13855 , NASA-RP-1062
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  • 9
    Publication Date: 2011-08-19
    Description: ISEE 3 data form the basis for a study of the evolution of the electron plasma in the magnetotail lobe and plasma sheet regions as a function of radial distance from the earth. The data were plasma electron and magnetometer measurements taken when the ISEE 3 was tailward of the earth during three different orbits. About 91,000 electron spectra were obtained in terms of the magnetosheath, lobe, plasma sheet and radial downstream distances. The lobe density peaked at 60 earth radii, while the sheet density tapered very slowly downstream. At large downstream distances (about 180 radii), the plasma bulk flow velocity increased significantly, surpassing the solar wind velocity. The bimodal electron flow angle near the earth became a single tailward flow at 180 radii.
    Keywords: GEOPHYSICS
    Type: Journal of Geophysical Research (ISSN 0148-0227); 89; 11007-11
    Format: text
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  • 10
    Publication Date: 2011-08-18
    Description: Using plasma electron and magnetic field measurements from ISEE 3, 220 earth radii from earth, it is found that the magnetotail at that distance is a coherent structure that evidently waves about through distances comparable to its own lateral scale size. For about one-third of the time it was inside the magnetotail, ISEE 3 was in the plasma sheet. During quiet times the plasma sheet is apparently quite thin, but in response to geomagnetic activity it expands, becoming filled with hot plasma flowing tailward at speeds sometimes exceeding 1000 km/sec, and forces the magnetotail cross-section itself to expand. The plasma sheet's expansion is delayed typically by about 30 minutes from the onset of the associated geomagnetic activity (often a clearly identified isolated substorm). The magnetic field in the newly-expanded plasma sheet usually exhibits a few-minute steep northward excursion followed by a more prolonged (and often steep) southward excursion. These are believed to be the signatures of arrival of a plasmoid formed and released near the earth at the onset of the corresponding geomagnetic activity. The discreteness of these plasma releases through the magnetotail and their close association with onsets of geomagnetic activity at earth suggest that they are consequences of spontaneous release, probably by magnetic reconnection, of energy and plasma earlier stored in the magnetotail.
    Keywords: GEOPHYSICS
    Type: Geophysical Research Letters (ISSN 0094-8276); 11; 5-7
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