trimethylsilyl derivative of 1-hydroxybenzotriazole 3-oxide
1,5-O,O-migration of the SiMe3 group
Springer Online Journal Archives 1860-2000
Chemistry and Pharmacology
Abstract Trimethylsilylation and methylation of 1 -hydroxybenzotriazole 3-oxide (1) proceed regioselectively and afford 1-trimethylsilyloxy- and 1-methoxybenzotriazole 3-oxides, respectively. The first compound easily undergoes fast hydrolysis and methanolysis, but does not react with nitroethane at 20 °C. A fast reversible 1,5-O,O-migration of the SiMe3 group is observed for this compound.
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