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  • 1
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Angewandte Makromolekulare Chemie 140 (1986), S. 33-40 
    ISSN: 0003-3146
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Description / Table of Contents: Die Reaktion von Natriumsilikat mit Dichlor-tetrakis(dimethylamino-cyclotriphosphazen) wurde unter verschiedenen experimentellen Bedingungen durchgeführt. Die Produkte waren weiße, klebrige Substanzen, die sich in stark polaren Lösungsmitteln lösten. Es wurde gefunden, daß das benutzte Dichlor-tetrakis(dimethyl-amino-cyclotriphosphazen) mit Silanol reagierte. Dabei wurde es in Form von Endgruppen eingebaut, denn das Molekulargewicht des Produkts war nicht höher als dasjenige eines Produktes, das aus Natriumsilikat allein hergestellt worden war.
    Notes: The reaction of sodium silicate with dichlorotetrakis(dimethylamino cyclotriphosphazene) was carried out under various experimental conditions. The products were white colored, adhesive materials and were soluble in high polar solvents. It was found that the dichlorotetrakis(dimethylamino cyclotriphosphazene) used reacted with silanol. It did not act as middle but as end group because the molecular weight of the product was not increased compared to that of the product derived from sodium silicate alone.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 24 (1990), S. 1385-1395 
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: To clarify involvement of complement activation in thrombus formation on polymer surfaces, in vitro complement activation was evaluated for polyethylene (PE) tubes radiation-graft copolymerized with acrylamide (AAm), acrylic acid (AC), 2-hydroxyethyl methacrylate (HEMA), Nvinylpyrrolidone (NVP), and vinyl alcohol (VOH), and compared to their in vivo antithrombogenicity and cell adherence in canine peripheral veins. The complement-activating surfaces (NVP and VOH) cause preferential adhesion of leukocytes and were more thrombogenic than the low complement-activating surfaces (AAm, PE, and HEMA). Infusion of naja haje cobra venom factor depressed leukocyte adhesion, followed by a marked decrease in thrombogenesis, for the strong classical-pathway-activating surface (NVP). Although estimation of in vitro activation for AC was inconclusive because of a large effect of adsorption, AC behaved like VOH in vivo. These results suggest that C5a(des Arg) mediated activation of leukocytes may play a role in thrombus formation by complement activation on polymer surfaces.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
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