ISSN:
0018-019X
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
(S,S)-N,N′ -Bis(aminoacyl)ethane- and (S,S)-N,N′ -bis(aminoacyl)propanediamines (AA-NN-2 and AA-NN-3, respectively, AA = alanine, phenylalanine, valine) were synthesized as the dihydrochlorides, and their complexes with Cu(II) studied potentiometrically. Since these ligands in the presence of Cu(II) are able to perform chiral resolution of D,L-dansylamino acids in HPLC (reversed phase), in a certain pH range (6.5-8.5), it is important to know the equilibria existing between ligands and copper in aqueous solution. For AA-NN-2, four species, CuLH3+, CuL2+, Cu2L2H-22+, and CuLH-2, were detected, whereas for AA-NN-3, only CuLH3+, CuL2+, and CuLH-2 were found. The aim is to find out which complexes may be involved in the recognition process.
Additional Material:
2 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/hlca.19860690818
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