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  • 1
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 22 (1976), S. 204-207 
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 18 (1976), S. 909-919 
    ISSN: 0006-3592
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The characteristic flavor of hard Italian cheeses is associated with the presence of fatty acids, particularly butyric acid, liberated from milk fat during the ripening process. To ensure proper development and control of flavor, animal pregastric esterases or lipases are routinely added to the milk before coagulation of the curd. Such esterases are also used to generate flavor in enzyme modified cheese and other dairy products.Esterases from microbial sources have been investigated as agents to enhance flavor in cheese. We have found that an esterase from Mucor miehei exhibits the type of lipolytic activity needed for this application. Romano and fontina cheeses of excellent quality have been prepared by the use of this esterase. It has also been used successfully in the preparation of enzyme modified cheese, and, in turn, processed American cheese.
    Additional Material: 10 Tab.
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  • 3
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 22 (1980), S. 1295-1296 
    ISSN: 0006-3592
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Acta Polymerica 48 (1997), S. 455-457 
    ISSN: 0323-7648
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: In situ conductivity measurements on the low band-gap polymer, poly-4-dicyanomethylene-4H-cyclopenta[2,1-b;3,4,b′]dithiophene have provided both p- and n-type conductivities as a function of the potential. A minimum in the conductivity, at a potential between the formal potentials for p- and n-doping, yields an intrinsic conductivity of 1.0 × 10-8 S cm-1, consistent with the optical band-gap of ∼0.8 eV.
    Additional Material: 3 Ill.
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  • 5
    Electronic Resource
    Electronic Resource
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 28 (1989), S. 2710-2710 
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    New York, N.Y. : Wiley-Blackwell
    Journal of Supramolecular Structure 7 (1977), S. 531-559 
    ISSN: 0091-7419
    Keywords: area-code hypothesis ; combinations of cell-surface recognition molecules ; chromosomal modifications ; DNA translocation ; multigene families ; immune system as developmental model ; Life Sciences ; Molecular Cell Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Numerous studies of embryogenesis have provided evidence for highly specific cell-surface recognition phenomena. These include both the interactions of neighboring cells and the specific cellular migrations which occur as the developmental program of the embryo progresses. The area-code hypothesis elaborated here is an attempt to provide a framework for understanding cell-recognition phenomena in development.This hypothesis is based on extensive genetic, molecular, and cellular studies of the immune system. These studies suggest that the following events occur during the differentiation of antibody-producing cells. (1) Somatic cell lines of antibody-producing cells undergo a modification of their DNA as they become committed to synthesize a particular type of antibody molecule. This chromosomal modification event is probably a DNA translocation which leads to a somatic rearrangement of certain antibody genes. (2) In each of the specific cell lineages the new arrangement of DNA is inherited by all subsequent generations of cells. (3) The developmental programs which control these genetic alterations may be employed in a programmed and reproducible fashion. This programming of antibody development is suggested because different embryos appear to become committed to the production of identical antibody molecules in the same developmental sequence. (4) Antibody molecules are initially displayed on the cell surface where they serve as highly specific receptors to trigger the cell to proliferate and differentiate upon interacting with appropriate external molecular signals. (5) Antibody-producing cells display combinations of different molecules on their surfaces which cause each of a very large number of different cells to interact differently with their environment. (6) The genes which code for many of these cell-surface molecules are organized into multigene families.These observations as well as information from other developmental systems have led us to propose the area-code hypothesis. This hypothesis is concerned with the structure, function, and regulation of cell-surface molecules that mediate recognition phenomena during embryogenesis. Area-code molecules are cell-surface molecules which are involved in the specific recognition phenomena during growth and development. These molecules provide cells with distinct cell-surface addresses or pheno-types, and provide the basis for the specificity in cell-cell recognition during cell migrations and cell-cell interactions, as well as serving as receptors for diffusible differentiation signals. The area-code hypothesis has 3 main postulates. (i) There is a progressive display of specific combinations of area-code molecules on the surfaces of cells during development. (ii) The genetic programs which determine the specific expression of area-code molecules are in part controlled by DNA modifications. These chromosomal modifications are believed to channel cells into specific lineages with progressively restricted developmental options. (iii) Many of the area-code systems are organized into multigene families. Rapid evolutionary increases in complexity may proceed by the duplication and subsequent independent evolution of multigene families. In short, many of the remarkable events which occur during the development of the immune system may form a basis for understanding other developmental systems. Some experimental approaches toward testing this hypothesis are discussed.
    Additional Material: 14 Ill.
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  • 7
    Electronic Resource
    Electronic Resource
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 25 (1988), S. 611-624 
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: The coupled heat and mass transfer partial differential equations as derived by Luikov are used to analyse freezing problems in porous media. A numerical model is subsequently developed to depict the frost heave mechanism in a freezing soil system. An example is given of the application of the model and the results are compared with those achieved from field experiments.Also, a novel application of the coincident node technique is presented for the coupled heat and mass transfer problem. This circumvents the numerical problems usually associated with flow through thin layers, in this case a vapour barrier, sandwiched between materials of greater thickness.
    Additional Material: 11 Ill.
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  • 8
    Electronic Resource
    Electronic Resource
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 28 (1989), S. 2711-2711 
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Chichester : Wiley-Blackwell
    Journal of Physical Organic Chemistry 4 (1991), S. 675-680 
    ISSN: 0894-3230
    Keywords: Organic Chemistry ; Physical Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: Several substituted bithiophenes were prepared and their electronic structure studied by photoelectron spectroscopy and semi-empirical MO calculations. Comparison of the spectra of related molecules and analysis of calculated molecular geometries gave an indication of molecular conformations in the gas phase.
    Additional Material: 6 Ill.
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  • 10
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 55 (1995), S. 1193-1196 
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: A series of block copolymers from D,L-lactide and poly(ethylene glycol) (PEG) with different molecular weight were synthesized by using Al(i-Bu)3—H3PO4—H2O as the initiator and identified by 1H-NMR, GPC, and DSC. The elongation at break of the material increased when PEG was introduced, but the strength of the material decreased. The copolymers degrade more smoothly in vitro than did the PLA homopolymer. © 1995 John Wiley & Sons, Inc.
    Additional Material: 4 Ill.
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