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  • 1
    Publication Date: 2002-10-01
    Print ISSN: 0261-4189
    Electronic ISSN: 1460-2075
    Topics: Biology , Medicine
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  • 2
    Publication Date: 2015-05-15
    Description: We present a new methodology that allows quantifying the impact of individual terms of the temperature and salinity conservation within the mixed layer on mixed layer depth (MLD). The method is applied to output from an ocean general circulation model in the Indian Ocean to investigate variability and changes in MLD. On seasonal timescales and for most areas of the Indian Ocean variability of MLD is tightly linked to all thermohaline budget terms. In the Indian Ocean at approximately 20 o S the MLD co-varies with surface heat and freshwater fluxes on intraseasonal and interannual timescales. The geography of the region includes the Leeuwin Current, plus the tropical eastern Indian Ocean for interannual surface freshwater fluxes. The range of seasonal amplitudes of MLD variability varies with individual budget terms but is typically within 1 m/month to 100 m/month. The ocean footprints of an intraseasonal tropical cyclone, tropical and mid-latitude seasonal temperature and salinity budgets and interannual variability associated with the Indian Ocean Dipole Mode are analyzed. The results reveal close relationships of the thermohaline budgets within the mixed layer with the variability of the MLD. The associated tendencies of changes in MLD are consistent with Argo and satellite-based observations of tendencies within the mixed layer and sea-surface temperature and salinity. This article is protected by copyright. All rights reserved.
    Print ISSN: 0148-0227
    Topics: Geosciences , Physics
    Published by Wiley on behalf of American Geophysical Union (AGU).
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  • 3
    Publication Date: 2015-05-13
    Description: The dramatic reduction in the number of observation data from the Tropical Atmospheric Ocean (TAO)/ Triangle Trans-Ocean Buoy Network (TRITON) array since 2012 has given rise to a need to assess the impact of those data in ocean Data Assimilation (DA) systems. This paper provides a review of existing studies evaluating the impacts of data from the TAO/TRITON array and other components of the Tropical Pacific Observing System (TPOS) on current ocean DA systems used for a variety of operational and research applications. It can be considered as background information that can guide the evaluation exercise of TPOS. Temperature data from TAO/TRITON array are assimilated in most ocean DA systems which cover the tropical Pacific in order to constrain the ocean heat content, stratification and circulation. It is shown that the impacts of observation data depend considerably on the system and application. The presence of model error often makes the results difficult to interpret. Nevertheless there is consensus that the data from TAO/TRITON generally have positive impacts complementary to Argo floats. In the equatorial Pacific, the impacts are generally around the same level or larger than those of Argo. We therefore conclude that with the current configuration of TPOS, the loss of the TAO/TRITON data is having a significant detrimental impact on many applications based on ocean DA systems. This conclusion needs to be kept under review because the equatorial coverage by Argo is expected to improve in the future.
    Print ISSN: 0035-9009
    Electronic ISSN: 1477-870X
    Topics: Geography , Physics
    Published by Wiley
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  • 4
    Publication Date: 2016-06-07
    Description: Stream microbial communities and associated processes are influenced by environmental fluctuations that may ultimately dictate nutrient export. Discharge fluctuations caused by intermittent stream flow are increasing worldwide in response to global change. We examined the impact of flow cessation and drying on in-stream nitrogen cycling. We determined archaeal (AOA) and bacterial ammonia oxidiser (AOB) abundance and ammonia oxidation activity in surface and deep sediments from different sites along the Fuirosos stream (Spain) subjected to contrasting hydrological conditions (i.e. running water, isolated pools and dry streambeds). AOA were more abundant than AOB, with no major changes across hydrological conditions or sediment layers. However, ammonia oxidation activity and sediment nitrate content increased with the degree of stream drying, especially in surface sediments. Upscaling of our results shows that ammonia oxidation in dry streambeds can contribute considerably (~50%) to the high nitrate export typically observed in intermittent streams during first flush events following flow reconnection. Our study illustrates how the dry channels of intermittent streams can be potential hotspots of ammonia oxidation. Consequently, shifts in the duration, spatial extent and severity of intermittent flow can play a decisive role in shaping nitrogen cycling and export along fluvial networks in response to global change. This article is protected by copyright. All rights reserved.
    Print ISSN: 0012-9658
    Electronic ISSN: 1939-9170
    Topics: Biology
    Published by Wiley on behalf of The Ecological Society of America (ESA).
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  • 5
    Publication Date: 2016-08-30
    Description: Atomic force microscopy is not only a high-resolution imaging device but also a mechanical machine, which can be used either to indent or stretch (soft) biomaterials. Due to the statistical nature of such materials (i.e., hydrogels or polymers) hundreds of force-distance curves are required to describe their mechanical properties. In this manuscript, we present an automated system for polymer unfolding detection based on continuous wavelet analysis. We have tested the automated program on elastin, which is an important protein that provides elasticity to tissues and organs. Our results show that elastin changes its mechanical behavior in the presence of electrolytes. In particular, we show that NaCl has a different effect on the contour length than CaCl 2 for similar unfolding forces. In addition, we provide the program in the supporting information for the researches facing such kind of problem.
    Print ISSN: 1059-910X
    Electronic ISSN: 1097-0029
    Topics: Natural Sciences in General
    Published by Wiley
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  • 6
    Publication Date: 2015-01-23
    Description: No instruments in the inner radiation belt are immune from the unforgiving penetration of the highly energetic protons (10s of MeV to GeV). The inner belt proton flux level, however, is relatively stable, thus for any given instrument, the proton contamination often leads to a certain background noise. Measurements from the Relativistic Electron and Proton Telescope integrated little experiment (REPTile) on board Colorado Student Space Weather Experiment (CSSWE) CubeSat, in a low Earth orbit, clearly demonstrate that there exist sub-MeV electrons in the inner belt because of their flux level is orders of magnitude higher than the background, while higher energy electron (〉1.6 MeV) measurements cannot be distinguished from the background. Detailed analysis of high-quality measurements from the Relativistic Electron and Proton Telescope (REPT) on board Van Allen Probes, in a geo-transfer-like orbit, provides, for the first time, quantified upper limits on MeV electron fluxes in various energy ranges in the inner belt. These upper limits are rather different from flux levels in the AE8 and AE9 models, which were developed based on older data sources. For 1.7, 2.5, and 3.3 MeV electrons, the upper limits are about one order of magnitude lower than predicted model fluxes. The implication of this difference is profound in that unless there are extreme solar wind conditions, which have not happened yet since the launch of Van Allen Probes, significant enhancements of MeV electrons do not occur in the inner belt even though such enhancements are commonly seen in the outer belt.
    Print ISSN: 0148-0227
    Topics: Geosciences , Physics
    Published by Wiley on behalf of American Geophysical Union (AGU).
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  • 7
    Publication Date: 2015-11-05
    Description: The highly efficient filtration of ultrafine dust emitted by biomass combustion processes with a baghouse filter has been tested successfully in the last years. To protect the filter material from the very small and sticky fine dust particles and to guarantee very high total collection efficiencies (〉99 %) in a long-term stable process, it is necessary to use a precoat. Tests done with a laboratory plant and a real application plant show that reusing of precoat materials can generate significant savings. Considering the influences of different combustion processes the associated Precoat Efficiencies could be calculated. With these characteristic ratios it is possible, to evaluate different process settings. Hence, the amount and the costs of the needed precoat could be reduced significantly.
    Print ISSN: 0930-7516
    Electronic ISSN: 1521-4125
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Published by Wiley
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  • 8
    Publication Date: 2012-09-13
    Description: Data assimilation methods have become increasingly popular to describe the outer radiation belt energetic electron environment. We use a Kalman filter with inputs of 1) electron phase space density (PSD) for constant first and second adiabatic invariants, μ = 2083[MeV/G] and K = 0.03[G1/2RE] respectively, from a five satellite data set (three LANL-GEO, one GPS, and Polar), and 2) a one-dimensional radial diffusion model with loss and source terms included. We augment the Kalman filter to include the intensity of local acceleration in the state vector. The output is an estimate of PSD for the radial range of the outer radiation belt and the time-dependent amplitude parameter of a Gaussian shaped source rate term for given location and width. To further constrain the source rate parameters, a root mean square (RMS) analysis of the observation residual vector (a.k.a. innovation vector) is performed in a parameter space of source location and width. We analyze five storm periods spanning from July 30th to October 24th of 2002, and each period's unique solution in the location-width parameter space is assimilated with the Kalman filter for a continuous reanalysis of the full 87 day period. The source amplitude parameter is analyzed for insight into time periods of enhanced local heating, suppressed loss, or, as the parameter can take negative values, additional loss. The source is found to peak in the recovery phases of the storms where the rate is sufficient to repopulate the radiation belt in approximately one day, suggesting that local heating is a major contributor to the electron radiation belts during the recovery phase.
    Print ISSN: 0148-0227
    Topics: Geosciences , Physics
    Published by Wiley on behalf of American Geophysical Union (AGU).
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  • 9
    Publication Date: 2012-07-12
    Description: We aimed to investigate the temporal variation of in-stream net dissolved inorganic nitrogen (DIN) areal uptake rates (UDIN, in μg N m−2 min−1) and its implications on regulating catchment N export, under base flow conditions. To do so, we estimated UDIN from longitudinal profiles of ambient DIN concentration (nitrate + ammonium) in two streams on a monthly basis during two hydrological years (n = 45). We found that in-stream DIN uptake and release did not offset each other (UDIN ≠ 0) in half of the dates, and that UDIN 〉 0 occurred mostly in autumn. Based on these reach-scale uptake rates, we performed empirical calculations and model simulations to assess the potential of stream network DIN retention to regulate DIN export from catchments on an annual scale. The empirical approach consisted in up-scaling UDIN by means of a dynamic stream network analysis that considered temporal and spatial variation of UDIN. The modeling approach consisted in applying different scenarios with the INCA model based on the natural range of empirical UDIN values. Our results showed that the contribution of stream network DIN retention to catchment DIN export increased when calculations accounted for the temporal variation of UDIN. Both approaches suggested that stream network DIN retention can significantly reduce DIN export from headwater catchments under base flow conditions (from 4% to 38%).
    Print ISSN: 0148-0227
    Topics: Biology , Geosciences
    Published by Wiley on behalf of American Geophysical Union (AGU).
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  • 10
    Publication Date: 2012-06-21
    Description: Natural glycosaminoglycans (GAGs) and chemically modified GAG derivatives are known to support osteogenic differentiation of mesenchymal stromal cells (MSC). This effect has mainly been described to be mediated by increasing the effectiveness of bone anabolic growth factors such as bone morphogenetic proteins (BMPs) due to the binding and presentation of the growth factor or by modulating its signal transduction pathway. In the present study, the influence of chondroitin sulfate (CS) and two chemically over-sulfated CS derivatives on osteogenic differentiation of human mesenchymal stromal cells (hMSC) and on BMP-2 and transforming growth factor β1 (TGF-β1) signalling was investigated. Over-sulfated CS derivatives induced an increase of tissue non-specific alkaline phosphatase (TNAP) activity and calcium deposition, whereas collagen synthesis was slightly decreased. The BMP-2-induced Smad1/5 activation was inhibited in the presence of over-sulfated CS derivatives leading to a loss of BMP-2-induced TNAP activity and calcium deposition. In contrast, the TGF-β1-induced activation of Smad2/3 and collagen synthesis were not affected by the over-sulfated CS derivatives. BMP-2 and TGF-β1 did not activate the extracellular signal-regulated kinase 1/2 or mitogen-activated protein kinase p38 in hMSC. These data suggest that over-sulfated CS derivatives themselves are able to induce osteogenic differentiation, probably independent of BMP-2 and TGF-β1 signalling, and offer therefore an interesting approach for the improvement of bone healing. J. Cell. Physiol. © 2012 Wiley Periodicals, Inc.
    Electronic ISSN: 1097-4652
    Topics: Biology , Medicine
    Published by Wiley
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