Publication Date:
2015-07-11
Description:
Article The EphA2 receptor tyrosine kinase is overexpressed in many cancers and is reported to be phosphorylated by Akt. Here, Zhou et al. show that RSK, rather than Akt, phosphorylates EphA2 on Ser-897, and this regulates cell migration and invasion of metastatic cancer cells. Nature Communications doi: 10.1038/ncomms8679 Authors: Yue Zhou, Naoki Yamada, Tomohiro Tanaka, Takashi Hori, Satoru Yokoyama, Yoshihiro Hayakawa, Seiji Yano, Junya Fukuoka, Keiichi Koizumi, Ikuo Saiki, Hiroaki Sakurai
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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