Publication Date:
2013-06-07
Description:
Article Although structural insights into antigen recognition by T cell receptors are increasingly available, the thermodynamic underpinnings are less well understood. Here the authors deconstruct the energetics of a representative interface and discover that peptide specificity, cross-reactivity and MHC restriction can be inextricably linked. Nature Communications 4 doi: 10.1038/ncomms2948
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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