Publication Date:
2018-11-15
Description:
Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways, Published online: 14 November 2018; doi:10.1038/s41467-018-06649-5 Melanocytic nevus count is associated with melanoma risk. In this study, a meta-analysis of 11 nevus GWAS studies identifies novel SNPs in KITLG and 9q32, and bivariate analysis with melanoma GWAS meta-analysis reveals that most nevus genes affect melanoma risk, while melanoma risk loci do not alter the nevus count.
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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