Publication Date:
2018-09-04
Description:
A systems-level framework for drug discovery identifies Csf1R as an anti-epileptic drug target A systems-level framework for drug discovery identifies Csf1R as an anti-epileptic drug target, Published online: 03 September 2018; doi:10.1038/s41467-018-06008-4 The identification of new drug targets is highly challenging, particularly for diseases of the brain. This study describes a general computational gene regulatory framework called CRAFT for drug target discovery, and the authors use CRAFT to identify the microglial membrane receptor Csf1R as a potential therapeutic target for epilepsy.
Electronic ISSN:
2041-1723
Topics:
Biology
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Chemistry and Pharmacology
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Natural Sciences in General
,
Physics
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