Publication Date:
2015-10-09
Description:
Article The physiological role of crosstalk between mesenchymal stem cells (MSC) and macrophages is unclear. Here, Phinney et al . show that MSCs transfer mitochondria to macrophages under oxidative stress, and desensitize macrophages to mitochondria by using microvesicles to repress Toll receptor signalling. Nature Communications doi: 10.1038/ncomms9472 Authors: Donald G. Phinney, Michelangelo Di Giuseppe, Joel Njah, Ernest Sala, Sruti Shiva, Claudette M. St Croix, Donna B. Stolz, Simon C. Watkins, Y. Peter Di, George D. Leikauf, Jay Kolls, David W. H. Riches, Giuseppe Deiuliis, Naftali Kaminski, Siddaraju V. Boregowda, David H. McKenna, Luis A. Ortiz
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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