Publication Date:
2014-03-30
Description:
Article CD8 expression levels on peripheral CD8+ T cells are regulated during development and effector differentiation. Here, the authors show that methylation patterns at the Cd8a locus, whose product is essential for surface CD8 expression, can change during T-cell development, activation, cytokine polarization and reprogramming. Nature Communications doi: 10.1038/ncomms4547 Authors: Kim L. Harland, E. Bridie Day, Simon H. Apte, Brendan E. Russ, Peter C. Doherty, Stephen J. Turner, Anne Kelso
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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