Publication Date:
2015-09-11
Description:
Article The inability to produce recombinant phosphoproteins has hindered research into their structure and function. Here the authors develop a cell-free protein synthesis platform to site-specifically incorporate phosphoserine into proteins at high yields, and recapitulate a MEK1 kinase signalling cascade. Nature Communications doi: 10.1038/ncomms9168 Authors: Javin P. Oza, Hans R. Aerni, Natasha L. Pirman, Karl W. Barber, Charlotte M. ter Haar, Svetlana Rogulina, Matthew B. Amrofell, Farren J. Isaacs, Jesse Rinehart, Michael C. Jewett
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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