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  • Bücher  (86)
  • MDPI - Multidisciplinary Digital Publishing Institute  (51)
  • Springer Nature  (35)
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  • 1
    Publikationsdatum: 2023-12-20
    Beschreibung: Climate change will bring about significant changes to the capacity of, and the demand on, water resources. The resulting changes include increasing climate variability that is expected to affect hydrologic conditions. The effects of climate variability on various meteorological variables have been extensively observed in many regions around the world. Atmospheric circulation, topography, land use and other regional features modify global changes to produce unique patterns of change at the regional scale. As the future changes to these water resources cannot be measured in the present, hydrological models are critical in the planning required to adapt our water resource management strategies to future climate conditions. Such models include catchment runoff models, reservoir management models, flood prediction models, groundwater recharge and flow models, and crop water balance models. In water-scarce regions such as Australia, urban water systems are particularly vulnerable to rapid population growth and climate change. In the presence of climate change induced uncertainty, urban water systems need to be more resilient and multi-sourced. Decreasing volumetric rainfall trends have an effect on reservoir yield and operation practices. Severe intensity rainfall events can cause failure of drainage system capacity and subsequent urban flood inundation problems. Policy makers, end users and leading researchers need to work together to develop a consistent approach to interpreting the effects of climate variability and change on water resources. This Special Edition includes papers by international experts who have investigated climate change impacts on a variety of systems including irrigation and water markets, land use changes and vegetation growth, lake water levels and quality and sea level rises. These investigations have been conducted in many regions of the world including the USA, China, East Africa, Australia, Taiwan and the Sultanate of Oman.
    Schlagwort(e): GE1-350 ; G1-922 ; meteorological variables ; water resources management ; uncertainty ; hydrological models ; climate models ; bic Book Industry Communication::K Economics, finance, business & management::KC Economics::KCN Environmental economics
    Sprache: Englisch
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  • 2
    Publikationsdatum: 2023-12-21
    Beschreibung: This handbook synthesizes and analyzes the growing knowledge base on life course health development (LCHD) from the prenatal period through emerging adulthood, with implications for clinical practice and public health. It presents LCHD as an innovative field with a sound theoretical framework for understanding wellness and disease from a lifespan perspective, replacing previous medical, biopsychosocial, and early genomic models of health. Interdisciplinary chapters discuss major health concerns (diabetes, obesity), important less-studied conditions (hearing, kidney health), and large-scale issues (nutrition, adversity) from a lifespan viewpoint. In addition, chapters address methodological approaches and challenges by analyzing existing measures, studies, and surveys. The book concludes with the editors’ research agenda that proposes priorities for future LCHD research and its application to health care practice and health policy.
    Schlagwort(e): R5-920 ; Developmental origins of chronic illnesses ; Autism ; Obesity ; Nutrition ; Health disparities across the lifespan ; Diabetes ; Community ; Fetal programming ; Health development science ; bic Book Industry Communication::M Medicine
    Sprache: Englisch
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  • 3
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    Springer Nature
    Publikationsdatum: 2023-12-20
    Beschreibung: This book aims to provide case studies and a general view of the main processes involved in the ecosystem shifts occurring in the high mountains, and to analyse the implications for nature conservation. Although case studies from the Pyrenees are preponderant, conclusions are aimed at any mountain range surrounded by highly populated lowland areas. The chapters give emphasis to approaches from environmental geography, functional ecology, biogeography, and paleoenvironmental reconstructions. The introductory and closing chapters summarize the main challenges that nature conservation may face in mountain areas under the environmental shifting conditions. This interdisciplinary book will appeal to researchers in mountain ecosystems, students and nature professionals.
    Schlagwort(e): GE1-350 ; nature conservation ; species distribution ; Pyrenees ; lakes ; forests ; bic Book Industry Communication::K Economics, finance, business & management::KC Economics::KCN Environmental economics
    Sprache: Englisch
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  • 4
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: The terrorist attacks on the World Trade Center towers on September 11, 2001, also referred as 9/11, was an iconic event in US history that altered the global and political response to terrorism. The attacks, which involved two planes hitting the twin towers in Lower Manhattan, New York City, resulted in the collapse of the buildings and over 2800 deaths of occupants of the buildings, fire, police and other responders and persons on the street in the vicinity of the collapsing buildings. The destroyed towers and the surrounding buildings have since been replaced but the health effects that resulted from the release of tons of dust, gases and debris as well as the life threat trauma are ongoing, and represent a major health burden among persons directly exposed. Hundreds of scientific publications have documented the physical and mental health effects attributed to the disaster. The current state-of-the-art in understanding the ongoing interactions of physical and mental health, especially PTSD, and the unique mechanisms by which pollutants from the building collapse, have resulted in long term pulmonary dysfunction, course of previously reported conditions, potential emerging conditions (e.g., heart disease and autoimmune diseases), as well as quality of life, functioning and unmet health care needs would be in the purview of this Special Issue on the 9/11 Disaster.
    Schlagwort(e): B1-5802 ; n/a ; asthma outcomes ; health insurance ; mental health ; handgrip strength ; WTC ; cognitive reserve ; disaster epidemiology ; surveillance bias ; cardiac sarcoidosis ; lung function ; lung injury ; treatment utilization ; injury ; Cox regression ; lower Manhattan residents ; chronic sinusitis ; social support ; indoor allergens sensitization ; respiratory function ; FDNY ; asthma control ; sarcoidosis ; asthma ; 9/11 impact ; physical health ; rescue/recovery workers ; chronic disease ; evidence-based treatment ; irritant(s) ; fibrosis ; unmet mental health care needs ; airway hyperreactivity ; asthma quality of life ; Short Form-12 (SF-12) ; WTC-related asthma ; longitudinal analysis ; forced oscillation ; thyroid cancer ; psychotherapy ; cognitive decline ; 9/11 disaster ; severe lung disease ; prevalence ; inflammation ; pulmonary function tests ; World Trade Center disaster ; disaster mental health ; epidemiological studies ; obstructive sleep apnea ; counseling ; sleepiness ; PTSD ; hazard function ; cleaning practices ; air pollution ; aging ; stressful life events ; airway physiology ; screening ; PTSD cluster ; latent class analysis ; retirement ; environmental health ; World Trade Center ; quality improvement ; pulmonary fibrosis ; WTC attack ; dust ; PCL score ; WTC responders ; mini asthma quality of life questionnaire ; biomarkers ; HQoL ; health-related quality of life ; Scadding stage ; 9/11 ; firefighters ; allergen exposure ; metabolic syndrome ; neuropathic symptoms ; small airway disease ; Asian Americans ; asthma morbidity ; PTSD symptom change ; WTC survivors ; trigger(s) ; World Trade Center exposure ; occupational exposure ; peripheral neuropathy ; disaster ; respiratory symptoms ; mental health treatment ; genetics ; mental health service utilization ; comorbid insomnia ; sleep-related quality of life ; World Trade Center attack ; immunoglobulin E ; mental health service use ; income loss ; paresthesia ; World Trade Center (WTC) ; fibrotic sarcoid ; depression ; post-disaster ; mental health conditions ; extrathoracic sarcoidosis ; medical imaging ; thema EDItEUR::Q Philosophy and Religion::QD Philosophy
    Sprache: Englisch
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  • 5
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    Springer Nature | Springer
    Publikationsdatum: 2024-04-14
    Beschreibung: In this concise yet comprehensive Open Access textbook, future inventors are introduced to the key concepts of Cyber-Physical Systems (CPS). Using modeling as a way to develop deeper understanding of the computational and physical components of these systems, one can express new designs in a way that facilitates their simulation, visualization, and analysis. Concepts are introduced in a cross-disciplinary way. Leveraging hybrid (continuous/discrete) systems as a unifying framework and Acumen as a modeling environment, the book bridges the conceptual gap in modeling skills needed for physical systems on the one hand and computational systems on the other. In doing so, the book gives the reader the modeling and design skills they need to build smart, IT-enabled products. Starting with a look at various examples and characteristics of Cyber-Physical Systems, the book progresses to explain how the area brings together several previously distinct ones such as Embedded Systems, Control Theory, and Mechatronics. Featuring a simulation-based project that focuses on a robotics problem (how to design a robot that can play ping-pong) as a useful example of a CPS domain, Cyber-Physical Systems: A Model-Based Approach demonstrates the intimate coupling between cyber and physical components, and how designing robots reveals several non-trivial control problems, significant embedded and real-time computation requirements, and a need to consider issues of communication and preconceptions.
    Schlagwort(e): Computer Systems Organization and Communication Networks ; Cyber-physical systems, IoT ; Simulation and Modeling ; Control, Robotics, Mechatronics ; Computer Engineering and Networks ; Cyber-Physical Systems ; Computer Science ; Control, Robotics, Automation ; CPS ; Embedded System ; model-based engineering ; hybrid systems ; Acumen ; coordinate transformations ; modeling computational systems ; modeling physical systems ; control ; sensing and actuation ; game theory ; Open Access ; Computer networking & communications ; Electrical engineering ; Cybernetics & systems theory ; Computer modelling & simulation ; Automatic control engineering ; Electronic devices & materials ; thema EDItEUR::U Computing and Information Technology::UT Computer networking and communications ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TH Energy technology and engineering::THR Electrical engineering ; thema EDItEUR::U Computing and Information Technology::UY Computer science::UYM Computer modelling and simulation ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TJ Electronics and communications engineering::TJF Electronics engineering::TJFM Automatic control engineering
    Sprache: Englisch
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  • 6
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-01
    Beschreibung: Canadian Pharmaceutical Scientists have a rich history of ground-breaking research in pharmacokinetics and drug metabolism undertaken throughout its Pharmacy and Medical Schools and within the Pharmaceutical and biotechnology industry. The principle of drug Absorption, Distribution, Metabolism and Excretion (ADME) is the foundational basis of rationale drug-design, and pharmacotherapy. The study of ADME and its descriptive quantitative analysis is the basis of pharmacokinetics. Pharmacokinetics is fundamental in the development of a new chemical entity into a marketable product and is essential in understanding the bioavailability, bioequivalence and biosimilarities of drugs. Pharmacokinetics and drug development studies facilitate an understanding of organ-based functionality. Population pharmacokinetic variability and the modeling of drug concentrations has significant utility in translating individual response in a target patient population. This special issue serves to highlight and capture the contemporary progress and current landscape of pharmacokinetics and drug metabolism within the prevailing Canadian context. We invite articles on all aspects of Pharmacokinetics and Drug Metabolism studies highlighting the world-class research currently undertaken in Canada for this special issue.
    Schlagwort(e): RM1-950 ; Pharmaceutical Sciences ; Canada ; Drug Metabolism ; Pharmacology ; Drug Delivery ; Pharmacokinetics ; thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology
    Sprache: Englisch
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  • 7
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    Springer Nature | Springer
    Publikationsdatum: 2024-03-24
    Beschreibung: This open access book describes the Reading Success project, in which a 5-step, assessment-to- intervention process, based on the Simple View of Reading, was used within a primary school setting in Australia to better support those students who struggle with reading. It provides an easily accessible overview of each step of the process involved in implementing this approach and highlights the crucial importance of collaboration between professionals involved in the teaching of reading within a school setting. It focuses on the decision-making processes used, such as rich dialogue with the leadership team and teachers, and shares participants’ perspectives gathered throughout the project. Using case studies, the book describes how the 5-step approach assists in creating detailed profiles of students’ strengths and weaknesses in spoken and written language skills that can be used to guide targeted intervention This book offers valuable insights for educators, speech pathologists, researchers, and pre-service teacher education students interested in the teaching of reading
    Schlagwort(e): Literacy ; Teaching and Teacher Education ; Speech Pathology ; Assessment, Testing and Evaluation ; Early Childhood Education ; Schools and Schooling ; Speech and Language Therapy ; Education ; simple view of reading ; the teaching of reading ; reading comprehension ; reading accuracy ; collaborative practice ; speech to print profile ; school-based literacy interventions ; speech pathologists in school ; reading success ; literacy success ; open access ; Teacher training ; Speech & language disorders & therapy ; Education: examinations & assessment ; Early childhood care & education ; Schools ; thema EDItEUR::C Language and Linguistics::CF Linguistics::CFC Literacy ; thema EDItEUR::J Society and Social Sciences::JN Education::JNM Higher education, tertiary education::JNMT Teacher training ; thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKZ Therapy and therapeutics::MKZL Speech and language disorders and therapy ; thema EDItEUR::J Society and Social Sciences::JN Education::JND Educational systems and structures::JNDH Education: examinations and assessment ; thema EDItEUR::J Society and Social Sciences::JN Education::JNL Schools and pre-schools::JNLA Pre-school and kindergarten ; thema EDItEUR::J Society and Social Sciences::JN Education::JNL Schools and pre-schools
    Sprache: Englisch
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  • 8
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-01
    Beschreibung: The year 2017 marks the 20th anniversary of the molecular cloning of the long sought-after capsaicin receptor, now known as TRPV1 (Transient Receptor Potential Vanilloid 1). This seminal discovery has opened up a “hot” new field of basic research and launched drug discovery efforts into the large family (by the latest count, 28 mammalian members and 27 in humans) of TRP ion channels. Indeed, it took less than a decade for the first potent, small molecule TRPV1 antagonists to enter phase 1 clinical trials, closely followed by TRPA1 and TRPM8 antagonists. The literature on TRP channels is immense. TRPV1 alone is a keyword in over 5000 publications searchable in PubMed. Clearly, it is not possible to capture the entire literature in a single thematic issue. Consequently, the selection of articles presented in this book represents a sampling of the literature, and is admittedly subjective. We tried to survey the wide range of human diseases in which TRP channels have been implicated, ranging from chronic pain through asthma and diabetes to cancer, and highlight the channels that appear to hold the greatest promise for therapeutic targeting. With this book, we hope to convince readers that TRP channels constitute a formidable family of potential therapeutic targets that will likely continue to demand attention.
    Schlagwort(e): RM1-950 ; resiniferatoxin ; pain ; TRPA1 ; TRPV3 ; TRPV1 ; TRP channels ; TRPM2 ; respiratory disorders ; permanent analgesia ; capsaicin ; TRPM7 ; cancer ; TRPM8 ; diabetes ; obesity ; thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology
    Sprache: Englisch
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  • 9
    Publikationsdatum: 2024-04-14
    Beschreibung: The goal of this book is simple: We would like to show how mortality dynamics can be visualized in the so-called Lexis diagram. To appeal to as many potential readers as possible, we do not require any specialist knowledge. This approach may be disappointing: Demographers may have liked more information about the mathematical underpinnings of population dynamics on the Lexis surface as demonstrated, for instance, by Arthur and Vaupel in 1984. Statisticians would have probably preferred more information about the underlying smoothing methods that were used. Epidemiologists likewise might miss discussions about the etiology of diseases. Sociologists would have probably expected that our results were more embedded into theoretical frameworks....
    Schlagwort(e): data ; lexis diagram ; mortality dynamics ; software ; Breast cancer ; Colorectal cancer ; Creative Commons license ; Human Mortality Database ; Life expectancy ; Lung cancer ; Seasonality ; United States ; thema EDItEUR::U Computing and Information Technology
    Sprache: Englisch
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  • 10
    Publikationsdatum: 2022-04-28
    Beschreibung: Environmental Monitoring/Analysis; Agriculture; Food Science; Plant Ecology; Animal Ecology; Marine & Freshwater Sciences
    Schlagwort(e): Environmental Monitoring/Analysis ; Agriculture ; Food Science ; Plant Ecology ; Animal Ecology ; Marine & Freshwater Sciences ; bic Book Industry Communication::K Economics, finance, business & management::KC Economics::KCN Environmental economics ; bic Book Industry Communication::K Economics, finance, business & management::KJ Business & management::KJM Management & management techniques::KJMV Management of specific areas ; bic Book Industry Communication::K Economics, finance, business & management::KN Industry & industrial studies::KND Manufacturing industries ; bic Book Industry Communication::R Earth sciences, geography, environment, planning ; bic Book Industry Communication::T Technology, engineering, agriculture
    Sprache: Englisch
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