Publication Date:
2015-06-19
Description:
Article Ovarian cancer is often accompanied by metastases at the time of diagnosis and has a poor survival rate. In this study, Aslan et al. identify a role for ZNF304 in ovarian cancer metastasis and show that the protein transcriptionally regulates β1 integrin, resulting in a reduction in programmed cell death. Nature Communications doi: 10.1038/ncomms8351 Authors: Burcu Aslan, Paloma Monroig, Ming-Chuan Hsu, Guillermo Armaiz Pena, Cristian Rodriguez-Aguayo, Vianey Gonzalez-Villasana, Rajesha Rupaimoole, Archana Sidalaghatta Nagaraja, Selanere Mangala, Hee-Dong Han, Erkan Yuca, Sherry Y. Wu, Cristina Ivan, Tyler J. Moss, Prahlad T. Ram, Huamin Wang, Alexandra Gol-Chambers, Ozgur Ozkayar, Pinar Kanlikilicer, Enrique Fuentes-Mattei, Nermin Kahraman, Sunila Pradeep, Bulent Ozpolat, Susan Tucker, Mien-Chie Hung, Keith Baggerly, Geoffrey Bartholomeusz, George Calin, Anil K. Sood, Gabriel Lopez-Berestein
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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