Publication Date:
2014-12-17
Description:
Article The transcription factor STAT3 regulates production of inflammatory cytokines by modulating NF-κB signalling. Here the authors show that STAT3 is a transcriptional repressor of the E2 ubiquitin-conjugating enzyme Ubc13, modulating NF-κB by regulating Ubc13 abundance. Nature Communications doi: 10.1038/ncomms6798 Authors: Huiyuan Zhang, Hongbo Hu, Nathaniel Greeley, Jin Jin, Allison J Matthews, Erika Ohashi, Mauricio S. Caetano, Haiyan S. Li, Xuefeng Wu, Pijus K. Mandal, John S. McMurray, Seyed Javad Moghaddam, Shao-Cong Sun, Stephanie S. Watowich
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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