Publikationsdatum:
2016
Beschreibung:
Implementation of pharmacogenetic‐guided warfarin dosing has been hindered by inconsistent results from reported clinical trials and a lack of available algorithms that include alleles prevalent in non‐white populations. However, current evidence indicates that algorithm‐guided dosing is more accurate than empirical dosing. To facilitate multiethnic algorithm‐guided warfarin dosing using preemptive genetic testing, we developed a strategy that accounts for the complexity of race and leverages electronic health records for algorithm variables and deploying point‐of‐care dose recommendations.
Print ISSN:
0009-9236
Digitale ISSN:
1532-6535
Thema:
Chemie und Pharmazie
,
Medizin
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