Publication Date:
2014-03-19
Description:
Article Platelet production has been suggested to occur by apoptosis of megakaryocytes, but mitochondrially mediated apoptosis is known to be dispensable. Here, the authors show that death receptor-mediated apoptosis in mouse megakaryocytes is also not required for platelet biogenesis. Nature Communications doi: 10.1038/ncomms4455 Authors: Emma C. Josefsson, Deborah L. Burnett, Marion Lebois, Marlyse A. Debrincat, Michael J. White, Katya J. Henley, Rachael M. Lane, Diane Moujalled, Simon P. Preston, Lorraine A. O’Reilly, Marc Pellegrini, Donald Metcalf, Andreas Strasser, Benjamin T. Kile
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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