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  • 1
    Electronic Resource
    Electronic Resource
    Die Wirkung von 4-Hydroxypentenal auf die phosphorylierende Atmung und auf verwandte Prozesse in Rattenlebermitochondrien (1972)
    Springer
    Monatshefte für Chemie 103 (1972), S. 1276-1284 
    Details
    ISSN: 1434-4475
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Zusammenfassung Der Mechanismus der durch 4-Hydroxypentenal (HPE) hervorgerufenen Atmungshemmung wurde untersucht. An Rattenlebermitochondrien hemmtHPE die phosphorylierende Atmung mit Glutamat; DNP kann diesen Effekt nicht aufheben. Die ADP-stimulierte Atmung mit Succinat wird gleichfalls durchHPE gehemmt; DNP ruft nur eine kurzzeitige Stimulierung hervor. Die Atmung fällt dann auf das Niveau des State 4. IstHPE in einer Konzentration anwesend, in der es noch keine Hemmung hervorruft, bewirkt die Zugabe von DNP in einer Konzentration (0,1mm), die normalerweise entkoppelt, eine Hemmung der ADP-stimulierten Succinatverarmung. Diese durchHPE + DNP induzierte Hemmung der Succinatoxydation verhält sich gegenüber erhöhtem Succinatangebot und Oligomycin wie die durch hohe DNP-Konzentrationen hervorgerufene Hemmung. HPE hemmt auch die DNP-stimulierte ATPase. Die in der Hemmung der Atmung und in der Hemmung der DNP-stimulierten ATPase zum Ausdruck kommenden Effekte vonHPE können auf die Hemmung des Phosphattransportes zurückgeführt werden.
    Notes: Abstract The mechanism of the respiratory inhibition caused by 4-hydroxypentenal (HPE) was studied. Observations on rat liver mitochondria indicate thatHPE inhibits phosphorylating respiration with glutamate as the substrate; DNP cannot cancel this effect. ADP-stimulated oxidation of succinate is also inhibited byHPE. The stimulating effect of DNP lasts only for about one minute, and then respiration falls to state 4 level. IfHPE is present in a concentration which by itself causes no inhibition, addition of DNP entails an inhibition of the ADP-stimulated oxidation of succinate even with uncoupling concentrations of DNP. ThisHPE + DNP induced inhibition of succinate oxidation is similar to the inhibition caused by high DNP concentration with respect to its reversibility by increased succinate concentration or oligomycin. The activity of the DNP-stimulated ATPase is depressed byHPE. Its seems that the inhibition of the phosphorylating system is due to an inhibition of phosphate transport.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00904512
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  • 2
    Electronic Resource
    Electronic Resource
    Expression of the Saccharomyces cerevisiae CYT2 gene, encoding cytochrome c1 heme lyase (1994)
    Springer
    Current genetics 25 (1994), S. 291-298 
    Details
    ISSN: 1432-0983
    Keywords: Cytochrome c 1 ; Cytochrome c 1 heme lyase ; GRF2p ; Glucose repression ; HAPp ; Saccharomyces cerevisiae
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract In this paper we examine the expression of the Saccharomyces cerevisiae CYT2 gene, which encodes cytochrome c 1 heme lyase. This enzyme is required for covalent attachment of heme to apocytochrome c 1, a subunit of the mitochondrial respiratory chain. Transcription of the 1-kb CYT2 mRNA initiates at four prominent sites at a distance of 52–225 bp in front of the AUG start codon. The level of CYT2 mRNA is not influenced by the presence or absence of oxygen or of heme, but it is subject to carbonsource control. The concentration of the CYT2 mRNA is significantly reduced in glucose-grown cells as compared to cells grown under non-repressing conditions. Neither the HAPp activator proteins nor MIG1p, a repressor protein involved in glucose repression, seem to mediate this effect.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00351480
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  • 3
    Electronic Resource
    Electronic Resource
    Comparing the landscape level perceptual abilities of forest sciurids in fragmented agricultural landscapes* (2000)
    Springer
    Landscape ecology 15 (2000), S. 523-533 
    Details
    ISSN: 1572-9761
    Keywords: chipmunks (Tamias striatus) ; connectivity ; dispersal ; fox squirrel (Sciurus niger) ; gray squirrel (Sciurus carolinensis) ; habitat isolation ; inter-patch movements ; perceptual range
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Perceptual range is the maximum distance from which an animal can perceive the presence of remote landscape elements such as patches of habitat. Such perceptual abilities are of interest because they influence the probability that an animal will successfully disperse to a new patch in a landscape. Furthermore, understanding how perceptual range differs between species may help to explain differential species sensitivity to patch isolation. The objective of this research was to assess the perceptual range of eastern chipmunks (Tamias striatus), gray squirrels (Sciurus carolinensis), and fox squirrels (Sciurus niger) in fragmented agricultural landscapes. Animals were captured in remote woodlots and translocated to unfamiliar agricultural fields. There they were released at different distances from a woodlot and their movements towards or away from the woodlot were used to assess their ability to perceive forested habitat. Observed perceptual ranges of approximately 120 m for chipmunks, 300 m for gray squirrels, and 400 m for fox squirrels, suggest that differences in landscape-level perceptual abilities may influence the occurrence of these species in isolated habitat patches.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1008154532512
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  • 4
    Electronic Resource
    Electronic Resource
    Expression of yeast cytochrome C1 is controlled at the transcriptional level by glucose, oxygen and haem (1992)
    Springer
    Molecular genetics and genomics 232 (1992), S. 447-459 
    Details
    ISSN: 1617-4623
    Keywords: Saccharomyces cerevisiae ; Cytochrome c 1 ; Promoter dissection ; HAP1, HAP2 transcription factors ; Centromere and promoter-binding factor (CPF1)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary The nuclear gene for cytochrome c 1 in Saccharomyces cerevisiae (CYT1) was localized on chromosome XV. Its upstream region was identified by functional complementation. Fusion to the lacZ reporter gene on a CEN plasmid allowed study of the effect of carbon sources and of specific deletion mutations on expression of the gene in yeast transformants. Detailed promoter analysis combined with expression studies in recipient strains defective in regulatory genes identified cis-acting sites and transcription factors involved in the regulated expression of the cytochrome c 1 gene. These analyses showed that, in the presence of glucose, transcription of CYT1 is positively controlled by oxygen, presumably through the haem signal, and mediated by the HAP1-encoded transactivator. It is additionally regulated by the HAP2/3/4 complex which mediates gene activation mainly under glucose-free conditions. Basal transcription is, in part, effected by CPF1, a centromere and promoter-binding factor.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00266250
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  • 5
    Electronic Resource
    Electronic Resource
    Mutation of a highly conserved base in the yeast mitochondrial 21S rRNA restricts ribosomal frameshifting (1995)
    Springer
    Molecular genetics and genomics 248 (1995), S. 207-216 
    Details
    ISSN: 1617-4623
    Keywords: Chloramphenicol resistance ; frameshifting Mitochondria ; 21S rRNA ; Yeast
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract A mutation shown to cause resistance to chloramphenicol inSaccharomyces cerevisiae was mapped to the central loop in domain V of the yeast mitochondrial 21S rRNA. The mutant 21S rRNA has a base pair exchange from U2677 (corresponding to U2504 inEscherichia coli) to C2677, which significantly reduces rightward frameshifting at a UU UUU UCC A site in a + 1 U mutant. There is evidence to suggest that this reduction also applies to leftward frameshifting at the same site in a − 1 U mutant. The mutation did not increase the rate of misreading of a number of mitochondrial missense, nonsense or frameshift (of both signs) mutations, and did not adversely affect the synthesis of wild-type mitochondrial gene products. It is suggested here that ribosomes bearing either the C2677 mutation or its wild-type allele may behave identically during normal decoding and only differ at sites where a ribosomal stall, by permitting non-standard decoding, differentially affects the normal interaction of tRNAs with the chloramphenicol resistant domain V. Chloramphenicol-resistant mutations mapping at two other sites in domain V are described. These mutations had no effect on frameshifting.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02190802
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  • 6
    Electronic Resource
    Electronic Resource
    Predation, scramble competition, and the vigilance group size effect in dark-eyed juncos (Junco hyemalis) (1999)
    Springer
    Behavioral ecology and sociobiology 46 (1999), S. 110-116 
    Details
    ISSN: 1432-0762
    Keywords: Key words Anti-predator behavior ; Food handling times ; Predation risk ; Scramble competition ; Sociality ; Vigilance ; Birds
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract In socially feeding birds and mammals, as group size increases, individuals devote less time to scanning their environment and more time to feeding. This vigilance “group size effect” has long been attributed to the anti-predatory benefits of group living, but many investigators have suggested that this effect may be driven by scramble competition for limited food. We addressed this issue of causation by focusing on the way in which the scan durations of free-living dark-eyed juncos (Junco hyemalis) decrease with group size. We were particularly interested in vigilance scanning concomitant with the handling of food items, since a decrease in food handling times (i.e. scan durations) with increasing group size could theoretically be driven by scramble competition for limited food resources. However, we showed that food-handling scan durations decrease with group size in an environment with an effectively unlimited food supply. Furthermore, this food-handling effect was qualitatively similar to that observed in the duration of standard vigilance scans (scanning exclusive of food ingestion), and both responded to changes in the risk of predation (proximity of a refuge) as one might expect based upon anti-predator considerations. The group size effects in both food-handling and standard scan durations may reflect a lesser need for personal information about risk as group size increases. Scramble competition may influence vigilance in some circumstances, but demonstrating an effect of competition beyond that of predation may prove challenging.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002650050599
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  • 7
    Electronic Resource
    Electronic Resource
    Anti-predatory vigilance and the limits to collective detection: visual and spatial separation between foragers (1996)
    Springer
    Behavioral ecology and sociobiology 38 (1996), S. 355-363 
    Details
    ISSN: 1432-0762
    Keywords: Key words Anti-predator behavior ; Birds ; Collective detection ; Vigilance
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Collective detection concerns the idea that all members of a socially feeding group are alerted to an attack as long as at least one group member detects it. We found that collective detection in mixed flocks of emberizid sparrows is limited markedly by relatively small degrees of visual and spatial separation between foragers. These limits on collective detection appear to influence the degree to which flock members lower their vigilance with increasing group size (the group size effect). Specifically, the decrease in collective detection with increasing visual and spatial isolation between foragers is accompanied by a concomitant decrease in the strength of the vigilance group size effect. Explanations for the vigilance-related effects of such separation based upon a bird’s ability to monitor the vigilance behavior of flockmates can be ruled out for our experimental system. Our results also shed light on the issue of whether the vigilance group size effect is influenced more by collective detection or the simple dilution of risk with increasing group size. We argue that collective detection is not only an important determinant of the group size effect, but also that the phenomena of collective detection and risk dilution are interdependent.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002650050252
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  • 8
    Electronic Resource
    Electronic Resource
    023 Qualitative and quantitative determination of metabolites of the lipid peroxidation product 4-hydroxynonenal from hepatocytes, enterocytes and tumor cells (1992)
    Springer
    Fresenius' Zeitschrift für analytische Chemie 343 (1992), S. 75-76 
    Details
    ISSN: 1618-2650
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00332017
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  • 9
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    023 Qualitative and quantitative determination of metabolites of the lipid peroxidation product 4-hydroxynonenal from hepatocytes, enterocytes and tumor cells (1992)
    Springer
    Details
    Publication Date: 1992-01-01
    Print ISSN: 0937-0633
    Electronic ISSN: 1432-1130
    Topics: Chemistry and Pharmacology
    Published by Springer
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  • 10
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    Exploring the implications of recreational disturbance on an endangered butterfly using a novel modelling approach (2013)
    Springer
    Details
    Publication Date: 2013-06-27
    Print ISSN: 0960-3115
    Electronic ISSN: 1572-9710
    Topics: Biology
    Published by Springer
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