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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of evolutionary economics 4 (1994), S. 141-150 
    ISSN: 1432-1386
    Source: Springer Online Journal Archives 1860-2000
    Topics: Economics
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1130
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract An amperometric detector based on the chemical modification of Nafion and indium (III) hexacyanoferrate (II, III) thin film (Nafion/In-CN-Fe) onto a glassy carbon (GC) electrode, was first successfully used for the determination of electroinactive cations (Li+, Na+, K+, Rb+, Cs+, NH4 +) in single column ion chromatography (IC). A set of well-defined peaks of electroinactive cations was obtained. The detection limits of the cations are 8.9 × 10–6 mol/L for Li+, 2.3 × 10–6 mol/L for Na+, 5.2 × 10–6 mol/L for K+, 4.8 × 10–6 mol/L for Rb+, 4.0 ׶10–6 mol/L for Cs+ and 5.3 × 10–6 mol/L for NH4 + at a single-to-noise ratio of 3. The proposed method was quick, sensitive and simple. The cations in rainwater and mineral water were successfully analyzed by this method.
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  • 3
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract In this study we have analysed the apolipoprotein (Apo) E polymorphism and polymorphisms of the ApoB gene, including the ApoB/Xba I and ApoB/4311 diallelic polymorphisms and a hypervariable region (HVR) situated in the 3′ region of the gene (ApoB/3′HVR), in a sample of healthy male subjects from Taiyuan (northern People's Republic of China). In comparison to Caucasian populations, in the Chinese sample, the Xba I2 allele (presence of cutting site; frequency 6.1%; and 95% confidence interval, 3.3–8.9) and the long HVR alleles (9.4%; 6.0–12.8) were rare, whereas the ApoB/4311 (Ser) allele (70.8%; 65.4–76.2) and the 34-repeat allele of the HVR (HVR34; 62.4%; 56.8–68.0) were frequent. In subjects having none, one, or two HVR34 alleles, the mean levels of plasma triglycerides were 2.32±1.44 (SD), 1.45+0.74, and 1.75±1.07 g/l, respectively (P 〈 0.007). Similar trends were observed for very low density lipoprotein (VLDL) cholesterol, LpE:B, and LpCIII:B. The frequencies of the ApoE alleles were similar to those reported in other populations of Asian origin; E2 (7.4%; 4.2–10.6), E3 (84.4%; 80.2–88.6), and E4 (8.2%; 5.0–11.4). Individuals carrying the E2 allele had a lower mean level of ApoB than E33 individuals: 0.87±0.16 and 1.00±0.22 g/l, respectively (P 〈 0.007). Individuals carrying the E4 allele had higher levels of ApoE than E33 individuals: 0.140±0.084 and 0.094±0.052 g/l, respectively (P 〈 0.004); similar trends were observed for VLDL cholesterol, triglycerides, LpE:B, and LpCIII:B. The ApoB/ HVR34 and ApoE/E4 polymorphisms accounted for 10% to 15% of the variability of the plasma levels of VLDL cholesterol, ApoE, triglycerides, LpE:B, and LpCIII:B. Several lipid variables appeared to be favourably affected by specific forms of ApoB and ApoE that are particularly frequent in this Chinese population.
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  • 4
    ISSN: 1432-0614
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Abstract The operon encoding aspartokinase and aspartate semialdehyde dehydrogenase was cloned and sequenced from rifamycin-SV-producing Amycolatopsis mediterranei U32 previously. In the present work, these two genes were introduced into the auxotrophic Escherichia coli strain CGSC5074 (ask −) and E. coli X6118 (asd −), respectively. The A. mediterranei U32 aspartokinase and aspartate semialdehyde dehydrogenase genes can be functionally expressed in E. coli and the gene products are able to substitute for the E. coli enzymes. Histidine-tagged aspartokinase and aspartate semialdehyde dehydrogenase were partially purified from E. coli cellular extracts and their kinetic characteristics were studied. Both aspartokinase and aspartate semialdehyde dehydrogenase showed typical Michaelis-Menten type substrate saturation patterns. Aspartokinase has K m values of 3.4 mM for aspartate and 2.3 mM for ATP, while aspartate semialdehyde dehydrogenase has K m values of 1.25 mM for dl-aspartate semialdehyde and 0.73 mM for NADP, respectively. Aspartokinase was inhibited by l-threonine, l-lysine, and l-methionine, but not by l-isoleucine and diaminopimelate. Aspartate semialdehyde dehydrogenase was not inhibited by any of the end-product amino acids at a concentration of less than 5 mM. Hill plot analysis suggested that aspartokinase was subject to allosteric control by l-threonine. Repression of both aspartokinase and aspartate semialdehyde dehydrogenase gene transcription in A. mediterranei U32 by l-lysine, l-methionine, l-threonine, and l-isoleucine were found. The network of regulation of aspartokinase and aspartate semialdehyde dehydrogenase in rifamycin SV-producing A. mediterranei U32 is presented.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Applied physics 59 (1994), S. 589-595 
    ISSN: 1432-0630
    Keywords: 78.20.Fm ; 07.60.−j ; 42.70.Nq
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract This paper presents an investigation of the polarizing optical behaviour of fibre-reinforced composites with mismatched refractive indices. Because of their optical heterogeneous nature, these composites are very poor in transparency and do not present fringe patterns when examined under plane polariscopes. To overcome these difficulties, a Laser Microscopic Analyser (LMA) was developed. The polarizing optical behaviour of the target composites are represented in terms of the curves of transmitted light intensity versus azimuthal angle (I-θ curves). It was found that these curves are of an unequal-fold pattern; this cannot be described by the Jones calculus. Some of the factors were studied for their relationships with the special morphology of I-θ curves. The unequal-fold feature was found to exist independently from the optical arrangements of the LMA. Other factors, such as fibre content, temperature and especially stress in the composites had a strong influence on the change of I-θ patterns. The regular changes of these parameters lead to regular changes in the I-θ pattern. The strange I-θ patterns are, therefore, believed to be connected with the optically anisotropic nature of the optically heterogeneous fibre-reinforced composites. This work is considered to be an important step for the further attempt of establishing a transmissive photoelastic method for optically heterogeneous fibre-reinforced composites.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1432-0630
    Keywords: PACS: 75.30.GW; 75.50.WW; 81.20.-N
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract. The effect of additive C on characterization of crystalline texture and magnetic properties of anisotropic melt-spun Sm(CoZr)7 alloy has been investigated. A few percent of C addition was found to not only significantly enhance the coercivity of the ribbons but also affect the characterization of crystalline texture. The easy-magnetization c axis is changed from parallel to the ribbon plane for SmCo6.5Zr0.5 ribbons, to normal to the ribbon plane for the SmCo6.5Zr0.5C0.5 one. Maximum energy product of SmCo6.5Zr0.5C0.5 ribbons prepared at 5 m/s, pulse magnetized to 5 T and measured normal or parallel to the ribbon plane is 8.6 MGOe or 3.2 MGOe, respectively. The domain structure was studied by magnetic-force microscope. A strip-shaped domain can be observed on the surface of the SmCo6.5Zr0.5 ribbons and the walls lie straight and parallel. For C-doped ribbons, the domain walls form a maze domain pattern of grains with c axis normal to the ribbon plane. Scanning electron micrography analysis showed that a dendrite structure was present in the SmCoZr ribbon surface. C addition leads to the diminishing of the above dendrite and the grains become equiaxial. The characterization of crystalline texture in C-free and C-doped ribbons has been correlated with their microstructure.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 46 (1994), S. 517-522 
    ISSN: 1432-1041
    Keywords: Capsaicin ; Diabetic neuropathy ; pain relief ; patients
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Abstract To undertake a quantitative overview of trials of topical capsaicin for the treatment of diabetic neuropathy, osteoarthritis, post-herpetic neuralgia, and psoriasis. A systematic search of the literature using both computerized and manual methods for identifying clinical trials of capsaicin. The trials identified were abstracted for response data, which then were analysed using established meta-analytic methods for both fixed and random effects modelling. The odds ratio of the response rate of subjects receiving topical capsaicin relative to that of subjects on placebo was used as the main outcome measure. The difference in the response rate was used as the response variable under the random effects model. When dropouts were mentioned and unambiguous assignment could not be made, the analysis was made on the basis of intention to treat. Capsaicin cream give more pain relief to patients with diabetic neuropathy than placebo did. The odds ratio (OR) and corresponding 95% confidence interval (95% CI) in favour of capsaicin cream were OR=2.74 (95% CI=1.73, 4.32). Using a random effect model the rate difference (RD) in favour of capsaicin cream was RD=0.25 (95% CI=0.15, 0.35). Capsaicin cream was also better than placebo in providing pain relief in osteoarthritis: OR=4.36 (95% CI=2.77, 6.88) and RD=0.29 (95% CI=0.20, 0.37) and in psoriasis: OR=2.80 (95% CI=1.69, 4.62) and RD=0.35 (95% CI=0.14, 0.56). There was, however, evidence of heterogeneity in the individual RDs in psoriasis, and complete blinding was difficulty because of the initial discomfort associated with topical capsaicin. In post-herpetic neuralgia the results were even less convincing. Topical capsaicin appears to be effective in the management of a variety of painful clinical conditions affecting the skin. However, totally blind trials are difficult to conduct with this substance. Future trials will need to address this problem more rigorously if a definitive answer about the effectiveness of capsaicin is to be obtained.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 53 (1998), S. 303-311 
    ISSN: 1432-1041
    Keywords: Key words Ibuprofen ; Analgesic effect
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Abstract Objective: To estimate the analgesic effect of ibuprofen and to test whether codeine and caffeine enhance its effect on post-surgical pain. Method: Systematic overview of the literature and meta-analysis of published randomised, controlled trials. Results: Ibuprofen is effective in dental pain, episiotomy pain and other post-operative pain. There is a dose–response relationship over the range 50–400 mg. The difference in total pain-relief score relative to placebo was 19–31%. On average, patients were over three times more likely to obtain moderate to excellent pain relief with ibuprofen than with placebo (response-rate ratio = 3.45) and the number needed to treat was 2.44. Codeine 60 mg enhanced the analgesic effect of ibuprofen 400 mg by about 8% in the total pain-relief scale, but it also increased its adverse effects. The additive effect of caffeine was inconsistent. Conclusion: Ibuprofen is an effective analgesic in postoperative pain. Codeine 60 mg adds to the analgesic effect of ibuprofen 400 mg. Any additive caffeine effect requires validation.
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  • 9
    ISSN: 1573-4889
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The simultaneous oxidation and sulfidation of Fe-25Cr, Fe-25Cr-5Al and Fe-25Cr-10Al alloys were studied at 1023, 1123, and 1223 K in H2-H2O-H2S gas mixtures. Fe-25Cr and aluminum-rich alloys with 0–10 wt.% Al show, in H2H2O-H2S gas mixtures at high temperatures, a transition from protective oxide-scale formation to the formation of a sulfide-rich corrosion product. The kinetics boundary, which indicates the transition from oxide formation with slow weight gains to sulfide formation with rapid weight gains, has been found in these three alloys. The critical oxygen partial pressures to stabilize oxide formation at the constant-sulfur partial pressures of aluminum-rich Fe-25Cr alloys were systematically below those of Fe-25Cr alloy. When the oxygen partial pressure is much higher than the critical one, the oxide scale formed on the Fe-25Cr alloy was mainly Cr2O3 with a small amount of FeCr2O4; on the other hand, the oxide scale formed on the aluminum-rich Fe-25Cr alloys was mainly Fe(Cr,Al)2O4 with a small amount of Al2O3 and Cr2O3. The thermodynamic stability diagrams for (Fe, Cr, Al) -S-O systems were constructed, and the experimental results which show the existence of Fe(Cr, Al)2O4 in the simultaneous sulfidation and oxidation of aluminum-rich Fe-25Cr alloys are explained by these diagrams. The reaction kinetics were measured by a stainless-steel spring balance, and the reaction products were characterized by x-ray diffraction, Auger spectroscopy, and scanning electron microscopy. The reaction rate usually decreased with an increase of the oxygen partial pressure at a constant sulfur partial pressure. The existence of aluminum plays an important role to suppress the sulfidation of Fe-25Cr alloys.
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  • 10
    ISSN: 1573-4889
    Keywords: simultaneous sulfidation and oxidation ; transition from protective oxide formation to sulfide formation ; titanium-, niobium-, and manganese-rich Fe-25Cr alloys ; Fe-25Cr alloy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The simultaneous sulfidation and oxidation of Fe-25Cr, Fe-25Cr-4.3Ti, Fe-25Cr-7.5Nb, and Fe-25Cr-9.0 Mn alloys were studied at 1023, 1123, and 1223 K, respectively, in H2-H2O -H2S gas mixtures. The influences of titanium, niobium, and manganese on the transition from protective oxide formation to the formation of sulfide-rich corrosion products of Fe-25Cr alloys have been investigated. It has been found that additions of titanium and niobium can improve the scaling resistance of Fe-25Cr alloys against sulfidation in H2 -H2O -H2S gas mixtures at high temperatures. However, the addition of manganese does not increase the resistance to sulfidation of Fe-25Cr alloy. The oxide Cr2Ti2O7, which can suppress sulfide formation, formed on the Fe-25Cr-4.3Ti alloy. The addition of manganese to Fe-25Cr does not form more stable and protective oxides than Cr2O3 which formed on Fe-25Cr. Thermodynamic stability diagrams are used to explain the experimental results.
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