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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 45 (1989), S. 726-728 
    ISSN: 1420-9071
    Keywords: GABA ; transport ; kidney ; brush-border membrane vesicles
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Brush-border membrane vesicles (BBMV) from rat kidney cortex possessed two uptake systems for γ-aminobutyric acid (GABA), a high affinity system (Km=10.9 μM) and a low affinity system (Km=1203 μM). Both uptake systems were inhibited by p-hydroxymercuribenzoic acid and ouabain, and by the action of neuraminidase, whereas the GABA analogs nipecotic acid, β-alanine, 2,4-diaminobutyric acid and 4,5,6,7-tetrahydroisoxazolo-[4,5c]-pyridin-3-ol had no effect on the GABA uptake activity. The BBMW uptake systems were clearly different from the GABA transport systems present in brain tissue.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 41 (1985), S. 259-261 
    ISSN: 1420-9071
    Keywords: Guinea pig small intestine ; myenteric neurons ; electrical behavior ; methylene blue ; neuronal membranes ; K+-conductance ; Ca++-dependent
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Intracellular recording methods were used to investigate the action of methylene blue on electrical behavior of myenteric neurons in guinea pig small intestine. The neurophysiological studies were done in parallel with studies on contractile activity of the intestinal musculature. Methylene blue depolarized the membranes, increased the input resistance, augmented excitability and reduced postspike hyperpolarizing potentials in AH/Type 2 myenteric neurons. These effects, with the exception of suppression of postspike hyperpolarization, were reversed by exposure to elevated calcium. The mechanism of action of methylene blue appeared to be suppression of calcium-dependent potassium conductance in the neuronal membranes. The neuronal action of methylene blue was manifest as a release of excitatory neurontransmitter substances with evoked contraction of the small intestinal longitudinal muscle.
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 41 (1985), S. 1156-1158 
    ISSN: 1420-9071
    Keywords: Forskolin ; intestinal secretion ; myenteric neurons, neural stimulation ; mucosal transport
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The effects of forskolin on myenteric neuronal activity and mucosal function were examined in guinea pig ileum. Forskolin increased the excitability of myenteric neurons, and increased mucosal chloride secretion by stimulating enteric neurons as well as by acting directly on enterocytes.
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Journal of materials science 13 (1978), S. 681-684 
    ISSN: 1573-4803
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Journal of materials science 35 (2000), S. 2909-2912 
    ISSN: 1573-4803
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract Infiltration trials have been conducted by filling Cu tubes withceramic powders and melting them under argon. No externalforces were applied; successful infiltration of the ceramicrelied solely upon favourable metal-ceramic wetting conditions.Oxides and covalently bonded compounds could not bespontaneously infiltrated but transition metal compounds such asNbC, Cr3C2, WC, NbB2 and Cr2N were. It was impossible toinfiltrate any ceramics when oxygen was present in the system.Contact angle data in the literature were found to predict, withfair reliability, infiltration events in Cu-ceramic systems.The good correlation is thought to be due to the ease with whichthe oxide film can be prevented from forming on molten Cu duringboth sessile droplet experiments and infiltration processing.
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Journal of materials science 9 (1974), S. 1999-2006 
    ISSN: 1573-4803
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract Very thin, highly perfect crystals of α-alumina of dimensions 0.5 to 10 μm with areas up to 5 cm2 have been obtained by transport of alumina in the vapour phase during the evaporation of solutions of alumina in lead fluoride. The crystals always contain at least one twin plane and appear to be a unique form. Surfaces are typically free from macroscopic growth steps and no dislocations have been detected by etching or electron microscopy. It is proposed that alumina transports via a gaseous complex and some evidence for growth of a VLS mechanism is presented. The presence of condensed lead compounds on the major (0001) surfaces evidently suppresses growth along the c-axis. Alumina transported by other vapour solvents tends to grow as a distinct bi-pyramidal form. The transport of oxides in other solvent/solute systems has been investigated. While many systems show evidence of vapour phase transport the crystal products are small and the transport process inefficient compared with that of the Al2O3-PbF2 system.
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  • 7
    ISSN: 1615-6102
    Keywords: NADPH oxidase ; Superoxide ; Kidney mesangial cell ; Fibroblast ; B lymphocyte ; Endothelial cell
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary NADPH oxidase of phagocytic leucocytes contains a membrane cytochromeb with two subunits, gp91 phox and p22 phox , together with three cytosolic proteins, p47 phox , p67 phox and p2 rac . The presence of some of these components has been sought in non-phagocytes, using Western blot analysis for protein expression and PCR to amplify and detect mRNA. All components were detected in EBV-transformed B lymphocytes and peripheral blood B lymphocytes. Fibroblasts and human kidney mesangial cells contained mRNA for p67 phox , p47 phox , and p22 phox but not gp91 phox . Levels of expression varied with growth conditions, but it appears possible than an isozyme of cytochromeb which lacks gp9 phox is present in these cells. Proteins of p47 phox and p67 phox were expressed, in low concentrations, in these two cell types. Expression of mRNA for p47 phox and p67 phox was found to be widespread in many cell types.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Experimental mechanics 29 (1989), S. 318-322 
    ISSN: 1741-2765
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract An existing method is extended to measure thermal strain distributions on an absolute basis. Free thermal expansion and stress-induced deformations are separated, allowing the determination of coefficients of expansion, stress-induced strains, normal stresses and shear stresses. The method is applicable to many steady-state and transient thermal-strain problems. A crossed-line grating is replicated on the specimen at elevated temperature. A zero-expansion mold is used for the replication, so that the grating frequency at the replication temperature can be retained to null the moiré interferometer at room temperature. When the specimen is viewed in the moiré interferometer, the fringe patterns reveal theU andV displacements induced by any change from the replication temperature. In addition, carrier fringe techniques are introduced for steady-state problems to subtract off the free thermal expansion and produce fringe patterns of the stress-induced deformations themselves. The method is demonstrated by analysis of a bimaterial plate subjected to a uniform change of temperature.
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  • 9
    Publication Date: 1989-08-01
    Print ISSN: 0014-4754
    Topics: Biology , Medicine
    Published by Springer
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  • 10
    Publication Date: 1985-09-01
    Print ISSN: 0014-4754
    Topics: Biology , Medicine
    Published by Springer
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