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  • 1
    Electronic Resource
    Electronic Resource
    Spectral covariance and fuzzy regions for image indexing (1997)
    Springer
    Machine vision and applications 10 (1997), S. 66-73 
    Details
    ISSN: 1432-1769
    Keywords: Key words: Color indexing – Color distribution features – Fuzzy sets – Performance evaluation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Notes: Abstract. To improve the discrimination power of color-indexing techniques, we encode a minimal amount of spatial information in the index. We tesselate each image with five partially overlapping, fuzzy regions. In the index, for each region in an image, we store its average color and the covariance matrix of the color distribution. A similiarity function of these color features is used to match query images with images in the database. In addition, we propose two measures to evaluate the performance of image-indexing techniques. We present experimental results using an image database which contains more than 11,600 color images.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001380050060
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  • 2
    Electronic Resource
    Electronic Resource
    The Kirkland-Larder Lake stratiform carbonatite (1978)
    Springer
    Mineralium deposita 13 (1978), S. 355-367 
    Details
    ISSN: 1432-1866
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Abstract The auriferous zone long known as the “Larder Lake Break” and more recently as the “Larder Lake Exhalite” is here interpreted as an exhalative kimberlitic carbonatite on the basis of its K, Ba, Sr, Mg, Fe, Cr, Ni and Co contents, and by comparison with similar younger rocks. Gold is believed to have been deposited syngenetically with this stratiform carbonatite and to be genetically related to late Archean tectonic, volcanic, petrochemical, sedimentary and exhalative processes. Rocks of the Timiskaming Series which host the carbonatite appear to represent a post-uplift graben assemblage of sedimentary and alkalic igneous rocks analagous to modern alkalic-carbonatitic complexes located in rifted upwarps. Preliminary data seems to indicate that carbonatite in general has a higher gold abundance than any other rock type, including iron formations and ultramafic rocks. Ferromagnesian carbonatites, the least common variety, may be worthy untested targets for gold exploration programs, particularly if some pyrite or other sulphide mineral is present.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00206569
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  • 3
    Electronic Resource
    Electronic Resource
    Reply to the discussion by R. S. Hyde (1980)
    Springer
    Mineralium deposita 15 (1980), S. 395-396 
    Details
    ISSN: 1432-1866
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00202804
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  • 4
    Electronic Resource
    Electronic Resource
    3-D Turbulent density field diagnostics by tomographic Moiré technique (1997)
    Springer
    Experiments in fluids 23 (1997), S. 76-85 
    Details
    ISSN: 1432-1114
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract  A novel whole-field optical method for mapping three-dimensional intensity of a turbulent density field is described. The method is based on the measurement of the local contrast degradation of Moiré fringes due to turbulence. For mapping the three-dimensional turbulence the tomographic technique was applied. The method was demonstrated by measuring the structure function constant of a hot, turbulent density jet. The results clearly show the high turbulent regions in the mixing shear layer at the jet edges and in the jet center, which corresponds to the wake behind the heating element of the jet generator. The optical setup is simple and can be automated. The method fits the tomographic technique and a high number of data values can be obtained from one record.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003480050088
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  • 5
    Electronic Resource
    Electronic Resource
    Dual hologram technique with enhanced sensitivity for measurements of weak phase objects (1997)
    Springer
    Experiments in fluids 22 (1997), S. 354-357 
    Details
    ISSN: 1432-1114
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract Conventional interferometric measurements of weak phase objects run into serious accuracy problems due to low sensitivity and/or optical aberrations. This paper describes an optical method, based on the dual hologram technique, with enhanced sensitivity and with compensating for the optical aberrations. It provides a reliable acquisition of the phase information from wide range of weak phase objects including high speed flow fields. The method was demonstrated by mapping the density field of a small size axisymmetric supersonic jet as a representative weak phase object.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003480050060
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  • 6
    Electronic Resource
    Electronic Resource
    Drug-induced chest pain and myocardial infarction. Reports to a national centre and review of the literature (1997)
    Springer
    European journal of clinical pharmacology 53 (1997), S. 105-110 
    Details
    ISSN: 1432-1041
    Keywords: Key words Myocardial infarction ; Drug induced ; Angina pectoris
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Abstract Objectives: To analyse reports of drug-induced myocardial infarction and chest pain sent to a national reporting centre. To review which drugs were suspected of exhibiting these adverse events and what mechanisms were involved. Methods: During the 20-year period 1975 through 1994, a total of 19 141 reports on adverse reactions to drugs were received by the Netherlands Centre for Monitoring of Adverse Reactions to Drugs. Of these 19 141 reports, 220 (1.1%) were concerned with drug-induced chest pain or myocardial infarction. After excluding reports in which the causal relationship was unlikely, poorly documented reports and reports on cases of overdosage, 183 reports (84%) were analysed. Results: There were 130 reports (71%) of drug-induced chest pain and 53 reports (29%) of drug-induced myocardial infarction. A total of 104 reports concerned females (57%). The most frequently reported suspected drugs were the antimigraine drug sumatriptan (33 reports, 4 concerning myocardial infarction), the calcium antagonist nifedipin (9 reports, 2 of myocardial infarction) and nicotine [9 reports (8 patches, 1 chewing gum), 5 concerning myocardial infarction]. There were 18 reports of a fatal outcome. Conclusions: Several drugs can produce chest pain or myocardial ischaemia. It is important to recognise drugs as a potential cause, especially in patients with normal coronary arteries.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002280050346
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  • 7
    Electronic Resource
    Electronic Resource
    Cough due to ace inhibitors: a case-control study using automated general practice data (1996)
    Springer
    European journal of clinical pharmacology 49 (1996), S. 439-444 
    Details
    ISSN: 1432-1041
    Keywords: Key words ACE inhibitors; cough ; epidemiological study ; general practice
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Abstract. Objectives: To determine the risk of coughing as an adverse reaction to ACE inhibitors under everyday circumstances in a large population, and to study whether this adverse effect was duration or dose dependent. Design: A population-based case-control study. Setting: Ten general practices of 14 Dutch general practitioners (GP), in which all consultations, morbidity and medical interventions, including drugs prescribed, were registered over the 18 month period from 1st September, 1992 to 1st March, 1994. Subjects: 1458 patients with incident coughing and up to four controls per case were obtained (total 4182 controls), matched for GP. All cases and controls were 20 years or older and had no record of respiratory infection, influenza, tuberculosis, asthma, chronic bronchitis, emphysema, congestive heart failure, sinusitis, laryngitis, haemoptysis or respiratory neoplasms during the study period. Results: Cases were 2.1-times more likely than controls to have been exposed to ACE inhibitors (95% CI 1.5–3.1), but after adjustment the odds ratio was 1.4 (95% CI 0.9–2.1). The crude odds ratio for captopril was 1.3 (95% CI 0.7–2.5), for enalapril 2.6 (95% CI 1.6–4.2) and for lisinopril 2.0 (95% CI 0.5–9.3). The adjusted odds ratio for captopril was 0.9 (95% CI 0.4–1.7), for enalapril 1.7 (95% CI 1.03–2.8) and for lisinopril 1.7 (95% CI 0.4–7.9). For patients who had been on ACE inhibitor treatment for no longer than 2 months the odds ratio was 4.8 (95% CI 1.7–13.3). The odds ratio declined to 2.0 (95% CI 1.1–3.8) for those who had taken an ACE inhibitor for 2–6 months, and to 1.6 (95% CI 0.9–2.7) for those on ACE-inhibitors for more than 6 months. Conclusion: The risk of coughing was increased twofold among ACE inhibitor users, but the odds ratios were no longer significant after controlling for several confounding factors. The risk of developing cough due to ACE-inhibitors declines with the duration of treatment, possibly due to depletion of susceptible persons.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002280050047
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  • 8
    Electronic Resource
    Electronic Resource
    Neuro-psychiatric effects of antimalarials (1997)
    Springer
    European journal of clinical pharmacology 52 (1997), S. 1-6 
    Details
    ISSN: 1432-1041
    Keywords: Key words Cohort study ; Mefloquine ; Proguanil ; Psychic adverse effects ; Antimalarial drugs
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Abstract Objective: To study the neuro-psychiatric adverse effects of antimalarial drugs. Setting: Persons who visited a Travel Clinic in Rotterdam over a period of 3 months. Design: Prospective cohort study on 394 persons taking mefloquine, 493 persons taking proguanil and 340 persons not taking antimalarial drugs who visited Africa, South America, Asia, or the Middle East. Methods: All persons received a structured questionnaire within 14 days of their return to the Netherlands. The questionnaire consisted of questions regarding use of alcohol, smoking, general health, medical history, tropical diseases during the trip, and other medicines, and contained an extensive list of general complaints regarding all body systems at four levels of severity. A modified and validated version of the Profile of Mood States was included. Results: In the study period, 2541 persons visited the Travel Clinic, of whom 1791 (70%) were both eligible and willing to co-operate. Of these 1791, data were obtained from 1501 (84%). Insomnia was most frequently encountered in users of mefloquine and mouth ulcers in proguanil users. After adjustment for gender, age, destination, and alcohol use, the relative risk for insomnia to mefloquine versus non-users of antimalarials was 1.6, and the excess risk was 6 per 100 users over an average period of 2 months. There were no significant differences between groups in depression, anxiety, agitation, and confusion. Stratification by gender demonstrated that insomnia was more common in women on mefloquine, but not in men. Also, women more frequently mentioned palpitations as an adverse event. After adjustment for age, destination, and alcohol use in women, the relative risks for insomnia and palpitations to mefloquine versus non-use of antimalarials were 2.4, and 22.5, respectively. When travellers were specifically asked for the adverse reactions they had experienced, anxiety, vertigo, agitation, and nightmares were significantly more frequently mentioned by mefloquine users. Conclusion: Insomnia was more commonly encountered during use of mefloquine than proguanil or during non-use of antimalarials.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002280050240
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  • 9
    Electronic Resource
    Electronic Resource
    Ad hoc tracing of a cohort of patients exposed to acitretine (Neotigason®) on a nation-wide scale (1992)
    Springer
    European journal of clinical pharmacology 42 (1992), S. 555-557 
    Details
    ISSN: 1432-1041
    Keywords: Acitretine ; Psoriasis ; ad hoc cohort tracing ; pharmacoepidemiology ; postmarketing surveillance ; adverse reaction monitoring
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary Etretinate has been detected in the blood of women taking acitretine. Because of the proven teratogenic effects of etretinate it was decided to try to trace all users of acitretine in The Netherlands via all drug dispensing outlets (1450 community pharmacies, 95 hospital pharmacies and 636 general practitioners). A request for information on the date of birth, sex, type of prescriber, and the number of capsules dispensed yielded a response rate of 87%. In 61% of all the responding dispensing outlets a prescription for acitretine had been filled. Of these 1153 outlets, 40% had dispensed acitretine to one patient and 52% had dispensed it to 2–5 patients. The 2717 patients comprised 1500 men (55%) and 1217 women, with mean ages of 48 and 53 y, respectively. As against 45% of all the male users, 31% of all the women were in the child-bearing age (15–45 y). The average numbers of dispensed capsules was 167 to users of 10 mg capsules, and 107 to users of the 25 mg capsules. In more than 80% of cases acitretine had been prescribed by dermatologists. Because the large majority of inhabitants in The Netherlands use one community pharmacy, and because most of them have automated records, it is possible to trace a cohort of users quickly and almost completely. Because most large-scale problems with adverse reactions are discovered within the first 2 years of marketing, at a time when exposure and morbidity registries are still collecting information, adhoc formation of a cohort in this way may be a useful resource for postmarketing surveillance.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00314869
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  • 10
    Electronic Resource
    Electronic Resource
    Glafenine-associated anaphylaxis as a cause of hospital admission in the Netherlands (1991)
    Springer
    European journal of clinical pharmacology 40 (1991), S. 367-371 
    Details
    ISSN: 1432-1041
    Keywords: Anaphylaxis ; glafenine ; contrast media ; hospital admission ; indomethacin ; penicillin ; adverse reaction monitoring ; postmarketing surveillance
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary In 1981 generalized anaphylaxis was registered on 166 occasions in Dutch general and academic hospitals. Clinical details of 120 of those patients revealed that in 107 anaphylaxis was either probable (n=90) or possible (n=17), whereas in 13 cases some other reaction than anaphylaxis had occurred. The series of confirmed cases contained 46 men and 61 women, with mean ages of 47 y and 48 y, respectively. There was a complete recovery in 102 patients and two patients died. Hypotension was present in 79 cases (74%), dyspnoea in 34 cases (32%) and a skin reaction, mainly urticaria, erythema or angioedema, was mentioned in 62 cases (58%). Most cases of anaphylaxis were drug-induced (76%), the main causes being the analgesic glafenine and contrast media. Glafenine was mentioned as the cause in 36% of all admissions for drug-induced anaphylaxis. Only 3.7% of cases had been reported to the voluntary reporting scheme of the Netherlands Centre for Monitoring of Adverse Reactions to Drugs. On the basis of reimbursement data, the risk of developing severe anaphylaxis to glafenine was estimated at 11.7–19.3-fold relative to indomethacin, and 13.4–20.2-fold relative to oral penicillins.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00265845
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