ISSN:
1573-1111
Keywords:
Copper(II) complex
;
functionalized cyclodextrin
;
LEC
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract The functionalized cyclodextrin 6-deoxy-6-[1-(2-amino)ethylamino]-β-cyclodextrin was synthesized, and an NMR, EPR, pH-metric, and calorimetric investigation was carried out in aqueous solution in order to ascertain its behaviour towards protonation and copper(II) complex formation. The thermodynamic parameters of the ternary complex formation with alanine, phenylalanine and tryptophan enantiomeric pairs were also determined (25° C andI=0.1 mol dm−3). No thermodynamic enantioselectivity was observed in these systems, while a chiral, though poor, discrimination was observed in LEC: c.d. spectra also show enantiomeric stereoselectivity. The results of the present investigation, compared with previously reported results, suggest the occurence of acis-complex ⇆trans-complex equilibrium in such systems.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00710226
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