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  • 1
    Electronic Resource
    Electronic Resource
    Tungsten skarn mineralizations in a regional metamorphic terrain in northern Norway: a possible metamorphic ore deposit (1991)
    Springer
    Mineralium deposita 26 (1991), S. 281-289 
    Details
    ISSN: 1432-1866
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Abstract Scheelite- and molybdenite-bearing scapolite skarn and plagioclase skarn occur as stratabound mineralizations in a terrain which has suffered regional metamorphism. Scapolite skarn formed as replacement skarns in plagioclase-bearing hornblendic gneiss whereas plagioclase skarn precipitated in fractures as vein skarn mineralizations. The genesis of these skarn deposits are closely connected to an episode of boudinage on the limbs of a large-scale dome-shaped fold. Fluid inclusion studies revealed that the ore-forming fluids were composed of CO2 with 2 to 17 mole% CH4, which formed due to decarbonation reactions during peak metamorphism at the end of the Caledonian orogenesis. Thermodynamic considerations indicate that scapolite and plagioclase formed above 550 °C and 2 Kbar pressure and were followed by precipitation of scheelite between 400 and 570 °C.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00191075
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  • 2
    Electronic Resource
    Electronic Resource
    Development and testing of a contamination potential mapping system for a portion of the General Separations Area, Savannah River Site, South Carolina (1998)
    Springer
    Environmental geology 35 (1998), S. 263-277 
    Details
    ISSN: 1432-0495
    Keywords: Key words Contamination potential ; Leakance ; Stacked-units ; GIS ; Isopachs
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Abstract  A methodology was developed to evaluate and map the contamination potential or aquifer sensitivity of the upper groundwater flow system of a portion of the General Separations Area (GSA) at the Department of Energy's Savannah River Site (SRS) in South Carolina. A Geographic Information System (GIS) was used to integrate diverse subsurface geologic data, soils data, and hydrology utilizing a stack-unit mapping approach to construct mapping layers. This is the first time that such an approach has been used to delineate the hydrogeology of a coastal plain environment. Unit surface elevation maps were constructed for the tops of six Tertiary units derived from over 200 boring logs. Thickness or isopach maps were created for five hydrogeologic units by differencing top and basal surface elevations. The geologic stack-unit map was created by stacking the five isopach maps and adding codes for each stack-unit polygon. Stacked-units were rated according to their hydrogeologic properties and ranked using a logarithmic approach (utility theory) to establish a contamination potential index. Colors were assigned to help display relative importance of stacked-units in preventing or promoting transport of contaminants. The sensitivity assessment included the effects of surface soils on contaminants which are particularly important for evaluating potential effects from surface spills. Hydrogeologic/hydrologic factors did not exhibit sufficient spatial variation to warrant incorporation into contamination potential assessment. Development of this contamination potential mapping system provides a useful tool for site planners, environmental scientists, and regulatory agencies.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002540050313
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  • 3
    Electronic Resource
    Electronic Resource
    Large-scale aquifer sensitivity model (1994)
    Springer
    Environmental geology 24 (1994), S. 34-42 
    Details
    ISSN: 1432-0495
    Keywords: Aquifer sensitivity ; Groundwater contamination ; Rating scheme
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Abstract A 480-square-mile region within Will County, in northeastern Illinois, was used as a test region for the development of a methodology to map the sensitivity of aquifers to contamination. An aquifer sensitivity model was developed using a geographic information system (GIS) to overlay and combine several data layers. The components used for our model are: (1) depth to sand and gravel or bedrock, (2) thickness of the uppermost sand and gravel aquifer, (3) glacial drift thickness, and (4) bedrock geology. The model is an improvement over many previous aquifer sensitivity models because it combines specific information on depth to the uppermost aquifer with information on the thickness of the uppermost sand and gravel aquifer. This county-wide model results in an aquifer sensitivity map that can be a useful tool for making land-use planning decisions regarding aquifer protection and management of groundwater resources.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00768075
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  • 4
    Electronic Resource
    Electronic Resource
    Lithogeochemical exploration for shale-hosted lead-zinc deposits: Case studies from the McArthur River and Mt Isa Districts, northern Australia (1989)
    Springer
    Mineralium deposita 24 (1989), S. 299-307 
    Details
    ISSN: 1432-1866
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Abstract The large lead-zinc deposits of Middle Proterozoic age in northern Australia occur in sediments interpreted as having been deposited under saline, shallow-emergent conditions. Significant alkaline diagenesis is evident from the presence of abundant K-feldspar and locally albite. Alkali element compositions clearly distinguish the sediments of the mineralised shallow-emergent locations both from those of more permanent water cover (lacustrine or lagoonal), and from those close to basin margins. The key variables for identifying the geochemical contrasts are the levels of K, Rb and Na, and the ratios of K : Al and K : Rb. These geochemical parameters can be used in conjunction with the levels of the target and indicator elements to detect whether mineralisation may be present in a favourable geological environment. Two case studies of the application of whole rock geochemistry in base metal exploration are given for the Glyde River Sub-basin (McArthur Basin) and the Western Succession, Mt Isa Block.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00206396
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  • 5
    Electronic Resource
    Electronic Resource
    Defective MHC class II expression in an MHC class II deficiency patient is caused by a novel deletion of a splice donor site in the MHC class II transactivator gene (2000)
    Springer
    Immunogenetics 51 (2000), S. 42-49 
    Details
    ISSN: 1432-1211
    Keywords: Key words Bare lymphocyte syndrome ; MHC class II deficiency ; MHC class II transactivator (CIITA) ; Immunodeficiency ; Gene regulation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract  MHC class II deficiency patients are mutated for transcription factors that regulate the expression of major histocompatibility complex (MHC) class II genes. Four complementation groups (A–D) are defined and the gene defective in group A has been shown to encode the MHC class II transactivator (CIITA). Here, we report the molecular characterization of a new MHC class II deficiency patient, ATU. Cell fusion experiments indicated that ATU belongs to complementation group A. Subsequent mutation analysis revealed that the CIITA mRNA lacked 84 nucleotides. This deletion was the result of the absence of a splice donor site in the CIITA gene of ATU. As a result of this novel homozygous genomic deletion, ATU CIITA failed to transactivate MHC class II genes. Furthermore, this truncated CIITA of ATU did not display a dominant negative effect on CIITA-mediated transactivation of various isotypic MHC class II promoters.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002510050007
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  • 6
    Electronic Resource
    Electronic Resource
    Molecular analysis of an MHC class II deficiency patient reveals a novel mutation in the RFX5 gene (1999)
    Springer
    Immunogenetics 49 (1999), S. 338-345 
    Details
    ISSN: 1432-1211
    Keywords: Key words MHC class II deficiency ; Bare lymphocyte syndrome ; RFX5 ; CIITA ; Gene regulation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract  Patients suffering from major histocompatibility complex (MHC) class II deficiency, a rare primary immunodeficiency, are characterized by a lack of MHC class II expression which is the result of defects in trans-acting factors. At least four complementation groups, A, B, C, and D, can be discerned. The gene affected in group C patients is known to be RFX5 and encodes one of the subunits of the multimeric phosphoprotein complex, RFX. In the present study we fused fibroblasts of a recently identified MHC class II deficiency patient, OSE, with fibroblasts derived from patients representative of each of the four complementation groups. Transient heterokaryon analysis indicated that OSE belonged to complementation group C. Furthermore, transfection of wild-type RFX5 cDNA into OSE fibroblasts resulted in restoration of the defect. Mutation analysis revealed that the RFX5 mRNA lacked four nucleotides and that this deletion was the consequence of a G to A transition in a splice acceptor site. Genomic oligotyping demonstrated that OSE was homozygous for the splice site mutation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002510050501
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  • 7
    Electronic Resource
    Electronic Resource
    Burst noise: Electrical breakdowns in myelinated nerve membrane (1980)
    Springer
    European biophysics journal 6 (1980), S. 88-88 
    Details
    ISSN: 1432-1017
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00647560
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  • 8
    Electronic Resource
    Electronic Resource
    Effect of rare earth cations on bactericidal activity of anionic surfactants (1987)
    Springer
    Journal of industrial microbiology and biotechnology 1 (1987), S. 377-381 
    Details
    ISSN: 1476-5535
    Keywords: Antimicrobial ; Metal salt ; Lanthanum ; Escherichia coli ; Staphylococcus aureus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Summary Rare earth metal cations are antibacterially synergistic with anionic surfactants, yielding mixtures that have bactericidal activity against a variety of gram-positive and gram-negative bacteria at minimum concentrations ranging from 16 to 125 μg/ml. Uptake of surfactant byEscherichia coli increases in the presence of lanthanum, suggesting that the role of rare earth metal cations is to reduce the net negative surface charge on the bacteria, thereby increasing the affinity between the negatively charged surfactant and the bacterial surface.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01569335
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  • 9
    Electronic Resource
    Electronic Resource
    Pollen and macrofossil analyses of a unique peat remnant of the former extensive peat bogs in West Friesland, The Netherlands: a detailed record of coastal raised bog formation (1992)
    Springer
    Vegetation history and archaeobotany 1 (1992), S. 185-188 
    Details
    ISSN: 1617-6278
    Keywords: Coastal peat bog ; Transitional Carex-Sphagnum peat ; Late Holocene ; The Netherlands
    Source: Springer Online Journal Archives 1860-2000
    Topics: Archaeology , Biology
    Notes: Abstract Of the former extensive peat bog in West Friesland, only small, buried and often cutover remains are left, scattered over a wide region. The results of pollen and macrofossil analyses of the most complete peat profile found to date in this district is presented in this paper. The vegetation development during the final stage of marine sedimentation in the vicinity of the analysed profile is reconstructed in some detail, as well as the subsequent formation of the lower layers of the mire, including the ombrotrophic peat. Apart from these aspects, the study also contributes to our knowledge of the Holocene palaeogeography of the coastal region of the Netherlands.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00191558
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  • 10
    Electronic Resource
    Electronic Resource
    Adsorption of hepatitis B surface antigen to matrix-bound long chain hydrocarbon structures (1976)
    Springer
    Cellular and molecular life sciences 32 (1976), S. 456-457 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The binding of hepatitis B surface antigen (HBsAg) to various matrix bound long-chain hydrocarbon structures has been studied. It was found that HBsAg was strongly bound to straight hydrocarbon chains with more than seven carbon atoms. The adsorbents can probably be used for removal and /or detection of hepatitis B infectious material.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01920793
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