ISSN:
1573-8221
Keywords:
multiple drug resistance
;
quinine
;
halidor
;
induced hyperglycemia
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract Quinine and halidor, modifiers of multiple drug resistancein vitro, did not abolish tumor resistance to doxorubicinin vivo, as was shown in male hybrid BDF1 mice with transplanted leukemia P 388 sensitive to doxorubicin and with induced resistance to it. Induced hyperglycemia did not lead to the manifestation of a therapeutic effect of doxorubicin in mice with leukemia P 388 sensitive to the antibiotic and with induced resistance to it.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02446746
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