ALBERT

All Library Books, journals and Electronic Records Telegrafenberg

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    European journal of nutrition 32 (1993), S. 163-175 
    ISSN: 1436-6215
    Keywords: Serum lipids ; coffee consumption ; smoking ; oral contraceptives ; Serum Lipide ; Kaffeekonsum ; Rauchen ; Orale Kontrazeptiva
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Medicine
    Description / Table of Contents: Zusammenfassung Unter Verwendung von Daten einer repräsentativen Gesundheits- und Ernährungsstudie über deutsche Erwachsene (1073 Frauen und 806 Männer) wurde der Zusammenhang von Kaffeekonsum und Serum-Cholesterinkonzentration und anderen Lipoproteinfraktionen geprüft. In multivariaten Modellanalysen, für Männer und Frauen getrennt durchgeführt, war für Alter, Body Mass Index, Rauchen, Gebrauch oraler Kontrazeptiva, sportliche Aktivität, Alkohol-, Fisch-, Fett-, Milch-und Teekonsum geprüft worden. Spezielles Interesse galt dem Einfluß von Rauchgewohnheiten sowie der Gebrauch oraler Kontrazeptiva auf die Beziehung zwischen Kaffeekonsum und den Serum-Lipidkonzentrationen. Im Vergleich zu geringer war höhere Kaffeezufuhr (〉400 ml/Tag) mit höheren Gesamt- und LDL-Cholesterin sowie niedrigeren triglyceridreichen Lipoprotein (TRL) und Triglycerid-Konzentrationen verbunden. Rauchen erwies sich in diesen Beziehungen als verstärkender Faktor. Die Ergebnisse der linearen Regression ergaben für Männer eine Erhöhung des LDL-Cholesterins um 1,66 mg/dL pro Tasse Kaffee, für Frauen eine Erhöhung um 1,58 mg/dL. In dieser Population war die Kombination von hohem Kaffeekonsum, Rauchen und bei Frauen der Nie-Gebrauch oraler Kontrazeptiva mit den höchsten Gesamt- und LDL-Cholesterin, sowie den niedrigsten TRL-Konzentrationen verbunden. Diese Befunde sind möglicherweise als Ergebnis erhöhter Aktivität der Lipoprotein-Lipase bei Kaffeekonsum interpretierbar.
    Notes: Summary Data from a representative health and nutrition survey of German adults (sample of 1073 women and 806 men) were used to investigate the relationship between coffee consumption and the concentration of cholesterol in serum as well as other lipoprotein constituents. For these outcome variables multivariate analyses were conducted separately for men and women. Differences in age, body mass index, smoking habits, use of oral contraceptives, physical activity, alcohol, fish, fat, milk and tea consumption were controlled for in the models. Interactions between coffee drinking behavior and smoking habits as well as between coffee and the use of oral contraceptives in their relationship with serum cholesterol were of special interest in the analyses. Higher coffee intake (〉400 ml/d) showed higher total cholesterol, LDL cholesterol and lower triglyceride rich lipoprotein (TRL) and triglyceride concentrations in serum compared to lower intake (〈200 ml/d). Smoking appeared to be an aggravating factor in these relationships. Results of the linear regression analysis demonstrated an increase of 1.66 mg/dL LDL-C per cup of coffee daily consumed for men and of 1.58 mg/dL for women. The combination of high coffee intake, smoking and no oral contraceptive use ever was associated with the highest total and LDL-C and lowest TRL concentrations in this population. The observed differences may be explained by an increase of lipoprotein lipase activity due to coffee consumption.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 2
    Publication Date: 1993-09-01
    Print ISSN: 0044-264X
    Electronic ISSN: 1435-1293
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Medicine
    Published by Springer
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 3
    ISSN: 1432-1041
    Keywords: Midazolam ; lipoprotein binding ; albumin binding ; plasma triglycerides ; intravenous lipid infusions ; severely ill patients
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary Severely ill patients often require total parenteral nutrition including intravenous liqid emulsions concurrently administered with lipophilic drugs. Therefore we investigated whether therapeutic application of a mixed medium chain/long chain triglyceride infusion affects the disposition of midazolam necessary for sedation in patients on artificial respiration. The concentrations of midazolam were measured in unfractionated plasma, and in lipoprotein fractions isolated from ex vivo blood samples, including determination of triglycerides and cholesterol; the albumin level was also analysed. Midazolam in the VLDL fraction was only 0.246 μg·ml−1, whereas the total plasma concentration averaged 1.101 μg·ml−1, and the midazolam content of the LDL plus HDL fractions amounted to 1.771 μg·ml−1. Albumin in these lipoprotein fractions was just as unequally distributed. A lipid infusion resulted in a significant elevation of total triglycerides from 157 to 221 mg·dl−1 and VLDL-triglycerides from 77 to 155 mg·dl−1. The triglyceride content of the LDL plus HDL fraction rose from 102 to 139 mg·dl−1. At the same time the midazolam concentration in unfractionated plasma and in the VLDL and the LDL + HDL fractions decreased to 0.899 μg·ml−1, 0.130 μg·ml−1, and 1.265 μg·ml−1, respectively. Cholesterol and albumin concentrations were not affected. The data show for the first time that a significant increase in plasma triglycerides during an intravenous lipid infusion does not result in accumulation of midazolam in lipoproteins, probably because albumin binding of the drug is very strong. The lack of midazolam trapping is important with respect to the safety of concurrent use of lipophilic drugs and intravenous lipid infusions.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Bulletin of mathematical biology 57 (1995), S. 401-411 
    ISSN: 1522-9602
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Mathematics
    Notes: Abstract Cannibalism can have a stabilizing effect in a predator-prey system. Contrary to the intuitive expectation cannibalism of the predator leads to an increase of the standing stocks of both, prey and predator.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 5
    ISSN: 1432-0827
    Keywords: Key words: Apolipoprotein E — Genetic — Bone fracture — Hemodialysis — Vitamin K.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Abstract. This investigation of 219 hemodialysis patients relates the history and prospective risk of bone fractures to apolipoprotein E (apoE) genotype. A greater percentage of the 41 patients with the E3/4 and E4/4 genotypes than of the 38 patients with the E2/3 and E2/2 genotypes had a history of bone fractures at the time of recruitment (44% versus 16%, P 〈 0.005). During the 4 years following recruitment, more of the patients with apoE genotypes E3/4 and E4/4 than with apoE genotypes E2/3 and E2/2 suffered bone fractures, but this difference was not statistically significant (17.1 versus 5.3%, P 〈 0.1). ApoE genotype appears to be an important genetic risk factor for bone fracture, possibly due to its previously reported influence on vitamin K concentrations in blood.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 6
    Electronic Resource
    Electronic Resource
    Springer
    European journal of nutrition 32 (1993), S. 219-228 
    ISSN: 1436-6215
    Keywords: Tocopherolkonzentration ; Cholesterinkonzentration ; Blut ; Vitamin-E-Versorgung ; Adjustierung ; Tocopherol concentration ; cholesterol concentration ; blood ; vitamin E status ; lipid-adjustment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Medicine
    Description / Table of Contents: Summary Measurement of α-tocopherol concentrations circulating either in plasma or serum is the most common method of measuring the vitamin E status in men. The analytical determination with a suitable HPLC method produces precise and reliable results. The interpretation of the measured α-tocopherol values is complicated by the strong positive correlation with different blood lipids. A considerable misinterpretation of the data will occur if these confounding factors are not taken into account by a suitable adjustment. Different methods have been described in the literature which tried to control the confounding effect of blood lipids. These methods were not completely satisfying. Therefore, a mathematical regression model, based on residuals, is introduced and applied to the data of the VERA-study (Verbundstudie Ernährungserhebung und Risikofaktoren Analytik) and the consequences of the lipid-adjustment of the tocopherol values are studied in further statistical procedures. Thereafter, lipid-adjusted tocopherol concentrations can be subjected to more extensive statistical evaluations without the requirement of special stratification.
    Notes: Zusammenfassung Zur Beurteilung der Vitamin-E-Versorgung des Menschen hat die Messung der α-Tocopherolkonzentration im Plasma oder im Serum eine weite Verbreitung gefunden. Mit Hilfe einer geeigneten HPLC-Methode kann die analytische Bestimmung heute sehr präzise und zuverlässig vorgenommen werden. Die Bewertung der α-Tocopherolkonzentration wird aber durch die enge positive Korrelation mit den verschiedenen Blutlipidfraktionen erschwert. Wird der Einfluß dieser Störvariablen bei der Bewertung der Meßwerte nicht durch ein Adjustierungsverfahren entsprechend berücksichtigt, kann dies beträchtliche Fehlbeurteilungen zur Folge haben. In der Vergangenheit wurden verschiedene Ansätze zur Kontrolle des Blutlipideinflusses auf α-Tocopherolkonzentrationen formuliert, die aber den Ansprüchen eines Ausgleichs nur unvollständig gerecht wurden. Am Datenmaterial der VERA-Studie (Verbundstudie Ernährungserhebung und Risikofaktoren Analytik) wird ein mathematisches Adjustierungsverfahren, das auf einem Regressionsansatz basiert, vorgestellt und in seinen Auswirkungen auf die Vitamin-E-Versorgungsmeßwerte überprüft. Durch diese Methode kann der Einfluß, den die Blutlipide auf die α-Tocopherolkonzentrationen ausüben, relativ einfach eliminiert werden. Die auf diese Weise lipid-adjustierten α-Tocopherolkonzentrationen stehen danach für weitergehende, statistische Auswertungen zur Verfügung, ohne daß noch eine spezielle Stratifizierung erforderlich ist.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Molecular and cellular biochemistry 19 (1978), S. 191-196 
    ISSN: 1573-4919
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Summary New theoretical considerations and a new approximation strategy were applied to the kinetic analysis of the experimental relationship between the reaction velocity in the steady state and the concentrations of ethanol and NAD. It could be shown that horse-liver ADH consists of two kinetically heterogeneous components.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 8
    Publication Date: 2016-11-01
    Print ISSN: 0043-6275
    Electronic ISSN: 1613-978X
    Topics: Economics
    Published by Springer
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 9
    Publication Date: 2013-03-01
    Print ISSN: 0967-3849
    Electronic ISSN: 1573-6849
    Topics: Biology
    Published by Springer
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 10
    Publication Date: 1992-01-01
    Print ISSN: 0031-6970
    Electronic ISSN: 1432-1041
    Topics: Chemistry and Pharmacology , Medicine
    Published by Springer
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...