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  • 1
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary In vivo treatment of the jejunal mucosa with glycosidic enzymes seems to remove the enteric surface coat of the enterocyte. As a consequence, the mucosa-to-serosa unidirectional flux of acetamide increases remarkably. The glycocalyx probably represents a barrier to the diffusion of small hydrosoluble solutes.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 39 (1990), S. 199-201 
    ISSN: 1432-1041
    Keywords: netilmicin ; pharmacokinetics ; diurnal variation ; circadian rhythm
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary Netilmicin 1.5 mg/kg body weight was administered intravenously every 8 h for 2 days to 8 patients with normal renal function. Significant elevation of mean and trough plasma concentrations was found at 05.00 h and 09.00 h. This was considered to be due to circadian variation, with possible accumulation during the night. The clinical importance of this phenomenon in relation to the development of aminoglycoside toxicity awaits further investigation.
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Journal of inclusion phenomena and macrocyclic chemistry 10 (1991), S. 453-469 
    ISSN: 1573-1111
    Keywords: Sodium deoxycholate and taurodeoxycholate ; acridine orange ; micelle-probe interaction
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract The structure of sodium deoxycholate (NaDC) micellar aggregates has been previously reported to be helical, and two helical models have been proposed for the micellar aggregates of sodium taurodeoxycholate (NaTDC). Here we report NMR and UV-VIS studies on the interaction between acridine orange (AO) and NaDC or NaTDC aqueous micellar solutions. AO is known to aggregate in aqueous solutions. The addition of NaDC or NaTDC causes the breaking of the AO aggregates, although the binding geometry of the two bile salts with AO seems to be slightly different. The cationic dye interacts mainly with the C18 and C,9 methyl groups of the bile salt molecules. This result agrees with one of the two NaTDC helical models and with some of its possible aggregates, and confirms again the helical structure attributed to the NaDC micellar aggregates within the limits of the experimental conditions tested by us.
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 28 (1972), S. 1182-1183 
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Riassunto Nell'intestino tenue di ratto in vivo è stato osservato che la concentrazione intracellulare di glucosio o di 3-O-metilglucosio, durante l'assorbimento di questi zuccheri, è sempre minore che nel siero. Ciò lascia presumere che esista una pompa per l'estrusione degli zuccheri a livello della membrana serosale delle cellule assorbenti intestinali.
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  • 5
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Riassunto La permeabilità all'acetamide dell'epitelio intestinale di digiuno di ratto non sembra influenzata dal grado di rigonfiamento delle cellule epiteliali.
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 20 (1964), S. 122-124 
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Riassunto Proseguendo precedenti ricerche si mette in evidenza che esiste una correlazione anche tra trasporto di sodio e trasporto di vari amino acidi attraverso l'intestino tenue isolato di ratto albino. Se ne deduce che presumibilmente ogni sostanza capace di essere trasportata attivamente stimola il trasporto di sodio e che quest'ultima funzione diventa solo un indice dell'attività totale di trasporto dell'epitelio intestinale.
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 22 (1966), S. 123-124 
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Riassunto Viene descritto un metodo polarografico per la determinazione continua del consumo di ossigeno in un preparato intestinale di ratto perfuso in vitro. I risultati ottenuti sono in accordo con quelli trovati da altri autori sullo stesso substrato mediante un metodo manometrico.
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 25 (1969), S. 603-604 
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Zusammenfassung Der Einfluss des Natriums auf die passive Permeabilität der Jejunum-Schleimhaut der Laboratoriumsratte gegenüber wasserlöslichen, nichtmetabolisierbaren und elektroneutralen Substanzen (Thioharnstoff, Azetamid) wurde untersucht. Wird das Natrium des NaCl in der Perfusionsflüssigkeit durch Trisoder Cholin-Kationen ersetzt, so nehmen sowohl der transepitheliale Glukosetransport wie auch die Mobilität der geprüften Substanzen ab.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Bulletin of engineering geology and the environment 58 (2000), S. 89-93 
    ISSN: 1435-9537
    Keywords: Key words Centrifuge modelling ; LNAPL migration ; Unsaturated sand ; Mots clés Modélisation par centrifugation ; Mouvement du LNAPL ; Sable partiellement saturé
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Description / Table of Contents: Résumé Des essais ont été réalisés avec l'équipement de centrifugation de l'Université de Technologie de Delft, aux Pays-Bas, afin d'étudier les mouvements de fluide non aqueux léger (LNAPL) dans un milieu granulaire non saturé. L'expérience a simulé un écoulement tri-phasique (air, eau, LNAPL) bi-dimensionnel dans un sable non saturé avec deux valeurs de porosité. Le choix de modéliser un écoulement bi-dimensionnel, couplé avec l'utilisation d'un réservoir transparent, a permis l'observation directe des processus au cours de l'expérience. Des lois d'échelle établies dans le cadre d'autres études ont été utilisées pour valider les résultats d'essais. Les essais ont été réalisés pour deux accélérations différentes afin de vérifier, en utilisant la "technique de la modélisation", les lois de similitude pour les différentes expériences. L'article présente en détail les méthodes expérimentales et les techniques de mesure utilisées pour évaluer les profils finals de teneur en eau et teneur en LNAPL dans les expériences.
    Notes: Abstract  Model tests were performed at the Geotechnical Centrifuge Facility of Delft University of Technology, The Netherlands, to examine the mechanics of light non-aqueous-phase liquid (LNAPL) movement in a partially saturated porous granular medium. The experiment simulated a two-dimensional three-phase flow (air, water, LNAPL) in unsaturated sand for two values of porosity. The choice of modelling a two-dimensional flow coupled with the use of a transparent strongbox enabled the direct observation of the progress of the experiments. Scaling laws developed in connection with other studies were used to validate the test results. Tests were conducted at two different gravity accelerations to verify, by means of the "modelling of models technique", the similitude between the different experiments. The paper presents details of the experimental methodologies and measuring techniques used to evaluate the final distribution of water and LNAPL content in the experiments.
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Cell biology and toxicology 12 (1996), S. 372-372 
    ISSN: 1573-6822
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
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