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  • 1
    Electronic Resource
    Electronic Resource
    Ganze Cremona-Transformationen von Primzahlgrad in der Ebene (1958)
    Springer
    Mathematische Annalen 136 (1958), S. 319-325 
    Details
    ISSN: 1432-1807
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01360237
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  • 2
    Electronic Resource
    Electronic Resource
    Ein Satz über ganze Cremona-Transformationen der Ebene (1955)
    Springer
    Mathematische Annalen 130 (1955), S. 11-19 
    Details
    ISSN: 1432-1807
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01343190
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  • 3
    Electronic Resource
    Electronic Resource
    Acrosin, the peculiar sperm-specific serine protease (1991)
    Springer
    Human genetics 〈Berlin〉 87 (1991), S. 635-641 
    Details
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The sperm enzyme acrosin has long been known as one of the key enzymes in the mammalian fertilization process. Elucidation of primary structures of preproacrosin from various species have allowed a deeper insight into the structural organization and the complex evolution of the sperm proteinase acrosin. In addition to the typical elements of serine proteases, the acrosin molecule possesses one novel domain that might convey DNA-binding properties.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00201716
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  • 4
    Electronic Resource
    Electronic Resource
    Detection of human spermatid-specific transcripts in peripheral blood lymphocytes of males and females (1991)
    Springer
    Human genetics 〈Berlin〉 87 (1991), S. 307-310 
    Details
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary We describe the detection of ectopic (“illegitimate”) transcripts of the proacrosin and protamine 2 genes, which are specific for human spermatogenesis, in non-cultured peripheral blood lymphocytes. After specifically-primed reverse transcription of total lymphocyte RNA, these rare transcripts can be directly visualised after two rounds of polymerase chain reaction with nested primers. Sequence and restriction analyses of the corresponding fragments have confirmed that transcripts of proacrosin and protamine 2 are present in the lymphocytes not only of males, but also of adult females.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00200909
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  • 5
    Electronic Resource
    Electronic Resource
    Physical mapping of two Xp markers DXS16 and DXS143 (1991)
    Springer
    Human genetics 〈Berlin〉 86 (1991), S. 418-420 
    Details
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Lymphocyte karyotyping of an infant girl with the clinical features of microphthalmia, iridoschisis, goiter, hip joint dysplasia, labium synechia and craniotabes revealed an Xp deletion. The lymphocyte karyotypes of the parents were normal. Bromodeoxyuridine incorporation studies showed that, in 42 out of 43 metaphases, the deleted X chromosome was late replicating. In one metaphase, the normal X chromosome was observed to be allocyclic. Using DNA markers from the Xp22 region, the breakpoint was assigned distal to DXS16 (pXUT23) and proximal to DXS143 (dic56). Dosage intensity measurements confirmed that the STS gene and the DNA marker DXS31 were involved in the deleted area. Restriction fragment length polymorphism analysis revealed that the paternally derived X-chromosome was deleted.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00201850
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  • 6
    Electronic Resource
    Electronic Resource
    Contrasting DNA sequence organisation patterns in sauropsidian genomes (1979)
    Springer
    Chromosoma 75 (1979), S. 199-214 
    Details
    ISSN: 1432-0886
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The genomic DNA organisation patterns of four sauropsidian species, namely Python reticularis, Caiman crocodilus, Terrapene carolina triungius and Columba livia domestica were investigated by reassociation of short and long DNA fragments, by hyperchromicity measurements of reannealed fragments and by length estimations of S1-nuclease resistant repetitive duplexes. While the genomic DNA of the three reptilian species shows a short period interspersion pattern, the genome of the avian species is organised in a long period interspersion pattern apparently typical for birds. These findings are discussed in view of the close phylogenetic relationships of birds and reptiles, and also with regard to a possible relationship between the extent of sequence interspersion and genome size.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00292208
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  • 7
    Electronic Resource
    Electronic Resource
    DNA sequence organisation in avian genomes (1978)
    Springer
    Chromosoma 69 (1978), S. 307-321 
    Details
    ISSN: 1432-0886
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract By means of renaturation kinetics of DNA of the three avian species Cairina domestica, Gallus domesticus and Columba livia domestica the following major DNA repetition classes were observed: a very fast reannealing fraction comprising about 15% of the DNA, a fast or intermediate reannealing fraction that makes up 10%, and a slow reannealing fraction of about 70%, which apparently renatures with single copy properties. — Comparing the reassociation behaviour of short (0.3 kb) and long (〉2 kb) DNA fragments of duck and chicken it becomes apparent that only 12% (duck) and 28% (chicken) of the single copy DNA are interspersed with repetitive elements on 2 to 3 kb long fragments. The lengths of the repetitive sequences were estimated by optical hyperchromicity measurements, by agarose A-50 chromatography of S1 nuclease resistant duplexes and by electron microscopic measurements of the S1 nuclease resistant duplexes. It was found that in the case of the chicken DNA the single copy sequences alternating with middle repetitive ones are at least 2.3 kb long; the interspersed moderate repeats have a length average of at least 1.5 kb. The sequence length of the moderate repeats in duck DNA is smaller. The results show that the duck and the chicken genomes do not follow the short period interspersion pattern of genome organisation, characteristic of the eucaryotic organisms studied so far.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00332134
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  • 8
    Electronic Resource
    Electronic Resource
    Non-repetitive DNA sequence divergence in phylogenetically diploid and tetraploid teleostean species of the family cyprinidae and the order isospondyli (1979)
    Springer
    Chromosoma 75 (1979), S. 185-198 
    Details
    ISSN: 1432-0886
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Non-repetitive DNA of anciently tetraploid teleostean species was analysed for the presence of duplicated sequences. Closely related diploid species were investigated in comparison. From the reassociation kinetics of total nuclear DNA, rate constants and fraction sizes of classes of repetitive and non-repetitive sequences were determined. DNA fractions enriched in the slowest renaturing sequence class were prepared and subjected to reassociation. The rate constants of these reactions were compared with the values expected for single-copy DNA from analytical genome size determinations. From reassociated DNA enriched in non-repetitive sequences also the melting temperatures were determined as a measure of internal base sequence heterogeneity. It has been shown that the two ancient tetraploids Cyprinus carpio and Thymallus thymallus are, with regard to the thermal stability of reassociated non-repetitive DNA, and with regard to the correspondence of reaction rates with the values expected for single copy DNA, indistinguishable from diploid controls (Rutilus rutilus, Clupea harengus and Sprattus sprattus). The tetraploid species Salmo irideus, Salvelinus fontinalis and Coregonus lavaretus appear as very recent tetraploids with regard to these criteria. The significance of the results for estimating the time of occurence of polyploidisation events in these taxa is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00292207
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  • 9
    Electronic Resource
    Electronic Resource
    Serological evidence for H-Y antigen in XO-female mice (1981)
    Springer
    Human genetics 〈Berlin〉 57 (1981), S. 68-70 
    Details
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary H-Y antigen was examined in XX-, XY-, and XO-mice using spleen, kidney, and liver cells of the animals for the absorption of the anti-H-Y antiserum produced in the rat. The cells of the XY- and XO-mice were found to be H-Y antigenpositive while the cells of the XX-mice were negative. As in Turner syndrome patients with 45,X, in the XO-female mice the H-Y antigen titre was reduced as compared to normal XY-male mice; intermediate values between those of normal male and female mice were obtained. These results clearly indicate that as in man, in the mouse the structural gene for H-Y antigen is not Y-linked but is located on an autosome. Furthermore, the concept of the regulation of the H-Y antigen gene expression in the human (Wolf et al. 1980a, b) by an X-linked repressor gene, escaping X-inactivation in the XX-female and an Y-linked inducer gene also seems to hold true in the mouse.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00271170
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  • 10
    Electronic Resource
    Electronic Resource
    H-Y antigen in male patients with X polysomies (1982)
    Springer
    Human genetics 〈Berlin〉 61 (1982), S. 110-112 
    Details
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary H-Y antigen was examined in eight male patients with X polysomies, namely four patients with 47,XXY, one patient with 48,XXXY, two patients with 49,XXXXY, and one patient with the mosaic 47,XXY/49,XXXXY. In all patients the H-Y antigen titers were lower than in normal 46,XY males. However, a linear correlation between the number of additional X chromosomes and the reduction of H-Y antigen titers could not be demonstrated. Such a correlation would be expected if the gene for the repressor of H-Y antigen expression is active also on the additional X chromosomes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00274198
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