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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Pure and applied geophysics 122 (1984), S. 878-893 
    ISSN: 1420-9136
    Keywords: Petatlan earthquake ; Foreshocks and aftershocks ; Asperities
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Notes: Abstract A close correlation in spatial distribution of local seismic activity and energy release patterns before and after the 1979 Petatlan, Mexico earthquake suggests heterogeneity within the fault plane of this major low-angle thrust event associated with subduction along the Middle America Trench. A simple two-asperity model is proposed to account for the complexity. Foreshocks and aftershocks of the neighboring 1981 Playa Azul earthquake showed a similar pattern. As both events occurred at the junction of the Orozco Fracture Zone and the Middle America Trench, we speculate that the observed complex fault plane is caused by subduction of the rugged ocean floor of the Orozco Fracture Zone. Short-term precursory seismicity prior to the Petatlan earthquake can be explained by using the asperity model and migration of a slip front from the south-east to the north-west across the main shock source region.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Economic theory 9 (1997), S. 283-307 
    ISSN: 1432-0479
    Keywords: C78
    Source: Springer Online Journal Archives 1860-2000
    Topics: Economics
    Notes: Summary A market in which population size is endogenously determined is modeled. Buyers and sellers are randomly matched upon entering the market, whereupon they engage in non-cooperative bilateral bargaining. It is shown that general matching technologies and heterogeneity of buyer or seller populations often result in multiple market equilibria. Up to four equilibria can occur and the equilibria can always be ranked according to population size. Under some conditions all equilibria can also be Pareto ranked. The set of equilibria depends on the relative population sizes of different types of potential entrant, market entry costs, and the degree of differentiation between agents on the same side of the market.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Economic theory 9 (1997), S. 283-307 
    ISSN: 1432-0479
    Keywords: JEL Classification: C78.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Economics
    Notes: Summary. A market in which population size is endogenously determined, is modeled. Buyers and sellers are randomly matched upon entering the market, whereupon they engage in non-cooperative bilateral bargaining. It is shown that general matching technologies and heterogeneity of buyer or seller populations often result in multiple market equilibria. Up to four equilibria can occur and the equilibria can always be ranked according to population size. Under some conditions all equilibria can also be Pareto ranked. The set of equilibria depends on the relative population sizes of different types of potential entrant, market entry costs, and the degree of differentiation between agents on the same side of the market.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Algorithmica 3 (1988), S. 53-77 
    ISSN: 1432-0541
    Keywords: Conservative algorithm ; Distributed random-access machine ; Fat-trees ; Load factor ; Parallel algorithms ; PRAM ; Tree contraction ; Treefix computation ; Volume-universal networks
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science , Mathematics
    Notes: Abstract This paper introduces a model for parallel computation, called thedistributed randomaccess machine (DRAM), in which the communication requirements of parallel algorithms can be evaluated. A DRAM is an abstraction of a parallel computer in which memory accesses are implemented by routing messages through a communication network. A DRAM explicitly models the congestion of messages across cuts of the network. We introduce the notion of aconservative algorithm as one whose communication requirements at each step can be bounded by the congestion of pointers of the input data structure across cuts of a DRAM. We give a simple lemma that shows how to “shortcut” pointers in a data structure so that remote processors can communicate without causing undue congestion. We giveO(lgn)-step, linear-processor, linear-space, conservative algorithms for a variety of problems onn-node trees, such as computing treewalk numberings, finding the separator of a tree, and evaluating all subexpressions in an expression tree. We giveO(lg2 n)-step, linear-processor, linear-space, conservative algorithms for problems on graphs of sizen, including finding a minimum-cost spanning forest, computing biconnected components, and constructing an Eulerian cycle. Most of these algorithms use as a subroutine a generalization of the prefix computation to trees. We show that any suchtreefix computation can be performed inO(lgn) steps using a conservative variant of Miller and Reif's tree-contraction technique.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Algorithmica 6 (1991), S. 5-35 
    ISSN: 1432-0541
    Keywords: Digital circuitry ; Graph theory ; Linear programming ; Network flow ; Optimization ; Pipelining ; Propagation delay ; Retiming ; Synchronous circuitry ; Systolic circuits ; Timing analysis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science , Mathematics
    Notes: Abstract This paper describes a circuit transformation calledretiming in which registers are added at some points in a circuit and removed from others in such a way that the functional behavior of the circuit as a whole is preserved. We show that retiming can be used to transform a given synchronous circuit into a more efficient circuit under a variety of different cost criteria. We model a circuit as a graph in which the vertex setV is a collection of combinational logic elements and the edge setE is the set of interconnections, each of which may pass through zero or more registers. We give anO(¦V∥E¦lg¦V¦) algorithm for determining an equivalent retimed circuit with the smallest possible clock period. We show that the problem of determining an equivalent retimed circuit with minimum state (total number of registers) is polynomial-time solvable. This result yields a polynomial-time optimal solution to the problem of pipelining combinational circuitry with minimum register cost. We also give a chacterization of optimal retiming based on an efficiently solvable mixed-integer linear-programming problem.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Environmental geology 19 (1992), S. 91-96 
    ISSN: 1432-0495
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Abstract Attempts to predict which geographic areas should be associated with a high percentage of homes with unusually high indoor radon levels have been based on estimates of soil radon and soil permeability for geological units. In northern Virginia and southern Maryland, it appears that predictions of indoor radon based on estimates of homesite soil radon and soil permeability are very useful.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Multimedia systems 5 (1997), S. 145-154 
    ISSN: 1432-1882
    Keywords: Key words:Constructionism – Distributed interactive simulation – Distributed objects – Graphical MUDs – Object-oriented simulation – Situated cognition – Virtual communities – Virtual worlds
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Notes: Abstract. ExploreNet is an experimental environment for creating and delivering networked “virtual worlds.” This system's style of user interaction was inspired by the concept of a “habitat” as first articulated in the LucasFilm's Habitat system. Players enter and interact in a habitat via their animated alter egos, called “avatars.” Habitats may be created for many purposes, including social interaction, entertainment and education. Our focus has been to facilitate the creation of habitats in which virtual communities of learners and mentors interact. This paper presents details of the current ExploreNet system, including its user interface, the means it provides for creating complex behaviors, details of its implementation, the outcomes of several experiments using this system, and our plans for its natural migration to a World Wide Web-based system.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular evolution 41 (1995), S. 430-439 
    ISSN: 1432-1432
    Keywords: Cytochrome proteins ; Molecular evolution ; Drosophila melanogaster ; Drosophila virilis ; Gene structure and sequence
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Cytochrome proteins perform a broad spectrum of biological functions ranging from oxidative metabolism to electron transport and are thus essential to all organisms. The b-type cytochrome proteins bind heme noncovalently, are expressed in many different forms and are localized to various cellular compartments. We report the characterization of the cytochrome b5 (Cyt-b) gene of Drosophila virilis and compare its structure to the Cyt-b gene of Drosophila melanogaster. As in D. melanogaster, the D. virilis gene is nuclear encoded and single copy. Although the intron/exon structures of these homologues differ, the Cyt-b proteins of D. melanogaster and D. virilis are approximately 75% identical and share the same size coding regions (1,242 nucleotides) and protein products (414 amino acids). The Drosophila Cyt-b proteins show sequence similarity to other b-type cytochromes, especially in the N-terminal heme-binding domain, and may be targeted to the mitochondrial membrane. The greatest levels of similarity are observed in areas of potential importance for protein structure and function. The exon sequences of the D. virilis Cyt-b gene differ by a total of 292 base changes. However, 62% of these changes are silent. The high degree of conservation between species separated by 60 million years of evolution in both the DNA and amino acid sequences suggests this nuclear cytochrome b5 locus encodes an essential product of the Drosophila system.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    The journal of membrane biology 23 (1975), S. 33-56 
    ISSN: 1432-1424
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Summary The sulfhydryl reagents Hg++ andp-chloromercuribenzene sulfonate (PCMBS) at millimolar concentrations reduced the mucosal entry of sugars and amino acids to 80–90% of control levels within several minutes. Based on 50% levels of inhibition, Hg++ proved to be 20 and 10 times as potent as PCMBS in blocking sugar and amino acid transport, respectively; both systems were equally sensitive to Hg++. Concomitant measurements of203Hg-PCMBS demonstrated a progressive tissue uptake, which, unlike inhibition, did not saturate with increasing times of exposure, thus suggesting appreciable epithelial entry with prolonged exposures (〉30 min at 1mm). At similar dose levels, no significant change in mucosal Na+ entry was detected. Inhibition was not reversed by 30-min washes in cholinesalt solutions; however, 10-min exposures to dithiothreitol [10mm] reversed Hg++ and PCMBS inhibition by 40 and 100%, respectively. Alanine and galactose influx kinetics measured at concentrations of 0–100mm exhibited a linear or diffusional entry component in addition to the usual saturable component for both control and Hg++-treated ileum. The presence of a diffusional term in the flux equation resulted in two sets of parameters giving nearly equal fits to these measurements. It was shown that this ambiguity could be resolved by determining the change in diffusional entry with Hg++ treatment. A 20-min exposure to 0.5mm Hg++ caused an increase from 0.050 and 0.045 to 0.064 and 0.070 cm/hr in the coefficient of diffusional entry for alanine and galactose, respectively. On the basis of this increase, it is argued that Hg++ causes a decrease inJ max and little change inK m for both transport mechanisms. This analysis has a general bearing on kinetic measurements of transport in which passive fluxes are comparable to those mediated by specific pathways. The alanine results are consistent with bimolecular reactions between mercurial and two membrane inhibitory sites, each producing ≈40% reduction in membrane translocation rate. The estimated reaction rate constants were 5.0 and 0.4mm min.
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    The journal of membrane biology 4 (1971), S. 156-164 
    ISSN: 1432-1424
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Summary Previous studies have shown that the bacterial exoenzyme phospholipase C permanently alters the chemical structure of erythrocyte ghosts. The present investigation has shown some of the functional, chemical and structural changes that sequentially occur when intact human red blood cells are lysed by this enzyme. Following exposure to the enzyme, membrane phospholipids were hydrolyzed with the removal of lipid phosphorus. This resulted in a shrinkage of cell size, sphering, and increased susceptibility to osmotic stress. Progressive hemolysis ensued, leaving ghosts which were characterized by focal electron-dense areas intimately associated with each membrane. These findings illustrate that the degradation of exposed phospholipids results in chemical and morphological damage to the cell membrane, which in turn alters its functional capabilities and results in lysis of the cell. Finally, these data support a newly proposed structural model of the cell membrane.
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