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  • Springer  (26)
  • Taylor & Francis  (1)
  • 1995-1999  (27)
  • 1
    ISSN: 1432-119X
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Abstract  Nasal mucosa covered by pseudostratified ciliated epithelia can be injured by microbial infection and physical and chemical agents. To elucidate mechanisms of regeneration, erosion of rat nasal mucosa was produced by intranasal instillation of trichloroacetic acid, and tissue specimens were then sequentially obtained after 1–14 days. Since tenascin-C (TN-C) and its receptor, α9β1 integrin, are assumed to play important roles in regeneration of stratified squamous epithelia, their expression was evaluated by immunohistochemistry and in situ hybridization. Three to five days after the injury, TN-C mRNA was found in epithelial cells of migrating fronts and in epithelial sheets recovering ulcerated surfaces between the fronts and normal regions. TN-C deposition was increased under such sheets. Enhanced α9 staining was also evident in the involved epithelium. 5-Bromo-2’-deoxyuridine incorporation assays revealed significant increase in proliferating cells in cell sheets over TN-C deposits at 3–7 days. Therefore, we conclude that regenerating epithelial cells produce and secrete TN-C, associated with an increase in α9 expression, and that interactions between these molecules could regulate migration and proliferation of the epithelial cells in an autocrine manner.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Springer
    Archives of environmental contamination and toxicology 36 (1999), S. 347-354 
    ISSN: 1432-0703
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Energietechnik , Medizin
    Notizen: Abstract. Inhalation pharmacokinetics of the environmental contaminants chloroform, bromodichloromethane, chlorodibromomethane, and carbon tetrachloride were evaluated, and their absorption amounts were estimated in rats to obtain fundamental data for risk assessment of chronic low-level exposures. Measured amounts of the substances were injected into a closed chamber system in which a rat had been placed, and the concentration changes in the chamber were examined. The pharmacokinetics of the substances were evaluated on the basis of the concentration-time courses using linear or nonlinear compartment models. The metabolic elimination amounts at various exposure concentrations were extrapolated using the estimated pharmacokinetic parameters. With exposure to chloroform, the fraction of the elimination amount at 1 ppb exposure (low concentration) against the exposure concentration was estimated to be 1.1 times higher than the fraction at 10 ppm exposure (high concentration). With exposure to low concentrations (1 ppb), extrapolation showed that more chloroform (0.33 nmol/h/kg) was absorbed by the rats than chlorodibromomethane (0.11 nmol/h/kg), bromodichloromethane (0.072 nmol/h/kg), and carbon tetrachloride (0.053 nmol/h/kg). Our findings revealed differences in the absorption amounts among the substances for the same exposure concentrations.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 3
    ISSN: 1438-1168
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Geologie und Paläontologie
    Beschreibung / Inhaltsverzeichnis: Zusammenfassung Südwestjünnan umfaßt den Jangtse und den Shan-Thai Mikrokontinent und den Simao Block. Das Gebiet wurde von aufeinander folgenden Subduktionsphasen einer ozeanischen Platte betroffen, auf die Kollision der Mikrokontinente und interkontinentales Rifting folgte. Dieses war mit basaltischem Vulkanismus während des späten Paläozoikums bis ins Mesozoikum assoziiert. Die triassischen Nanjian-Basalte, die auf dem Jangtse Mikrokontinent eruptierten, haben mehr angereicherte Isotopenverhältnisse und höhere LREE/HFSE und LREE/HREE Verhältnisse. Dieses weist auf eine angereicherte subkontinentale Lithosphäre unter dem Jangtse Mikrokontinent hin, die sich während langer Perioden der Erdgeschichte stabilisierte (〉2Ga). Die mittel jurassischen Simao-Basalte haben eine mehr verarmte geochemische Signatur aber auch Elementanreicherungen, die für ein Subduktionszonen-Milieu charakteristisch sind, obwohl die Basalte in einem interkontinentalen Graben ausgetreten sind. Man kann daraus schließen, daß der lithosphärische Mantel des Simao-Blockes durch Subduktionsprozesse während des jüngsten Karbons bis in die späte Trias vor dem Beginn des mittel-jurassischen kontinentalen Riftings modifiziert worden war. Das Fehlen einer Korrelation zwischen der Anreicherung von HFSE, Y und HREE und relativ angereicherter Nd-Isotopenverhältnisse weist darauf hin, daß die Verarmung der Quelle der Simaobasalte nicht weit zurückreicht. Sie dürfte viel eher gleichaltrig mit der subduktions-bedingten Anreicherung durch Mantel-Metasomatose kurz vor der Entstehung der Basalte sein. Die mittel-jurassischen Baoshan-Basalte, die während des kontinentalen Riftings auf den Shan-Thai Mikrokontintent eruptierten, haben eine Sr-Nd-Isotopensignatur, die ähnlich der Gesamterde ist, jedoch höhere Konzentrationen inkompatibler Spurenelemente zeigt. All dies legt nahe, daß die subkontinentale Lithosphäre unter dem Shan-Thai-Mikrokontinent kurz vor der Eruption der Baoshan-Basalte von Mantel-Metasomatose betroffen worden ist.
    Notizen: Summary Southwestern Yunnan, comprising the Yangtze and Shan-Thai microcontinents and the Simao block, has successively undergone subduction of an oceanic plate, followed by a collision of the microcontinents and intracontinental rifting associated with basaltic volcanism during Late Paleozoic to Mesozoic. The Triassic Nanjian basalts, erupted on the Yangtze microcontinent, have more enriched isotopic ratios and higher LREE/HFSE and LREE/HREE ratios. This suggests the existence of an enriched subcontinental lithosphere under the Yangtze microcontinent which stabilized over long periods of the earth's history (〉 2Ga). The Middle Jurassic Simao basalts have more depleted geochemical features and also have element enrichments characteristic of a subduction zone environment, although the basalts were erupted in an intracontinental graben. It may be inferred that the lithospheric mantle of the Simao block was modified by subduction processes during Latest Carboniferous to Late Triassic prior to the onset of the Middle Jurassic continental rifting. The lack of correlation between depletion of HFSE, Y and HREE, and relative enriched Nd isotopic ratios suggests that the source depletion of the Simao basalts is not an old feature and has been contemporaneous with the subduction-related enrichment through mantle metasomatism shortly before the basalts were produced. The Middle Jurassic Baoshan basalts which erupted during the continental rifting on the Shan-Thai microcontinent have an Sr-Nd isotopic composition similar to the bulk earth and higher concentrations of incompatible trace elements. These features suggest that the subcontinental lithosphere under the Shan-Thai microcontinent underwent mantle metasomatism just prior to eruption of the Baoshan basalt.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 4
    ISSN: 1435-1536
    Schlagwort(e): Sodium di-n-pentyl phosphate ; phase diagram ; phase structure
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Chemie und Pharmazie , Maschinenbau
    Notizen: Abstract Sodium di-n-pentylphos phate (DPP) has been synthesized, and the phase diagram of the DPP-water system consisting of five regions (I, II, III, IV, and V) has been determined. The phase structure has been investigated by1H pulsed-gradient NMR self-diffusion,31P NMR and x-ray low angle diffraction methods. The results are summarized as follows. In region I, there exist two critical micelle concentrations (CMC), indicating that this region is in a monomer-micelle equilibrium and that variation in the aggregated state occurs at the second CMC. Region II is a two phase area in which regions I and IV coexist. In region III, hydrated crystals and an aqueous solution of DPP coexist. Region IV is a homogenous, transparent and fluid phase and the results of31P NMR spectra and x-ray diffraction patterns reveal the formation of a highly organized structure, similar to a lamellar-like structure. Region V is a homogenous, transparent and fluid phase and the self-diffusion coefficient value and31P NMR spectra show that its phase structure is very similar to that for the concentrated sample in region I.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 5
    Digitale Medien
    Digitale Medien
    Springer
    Journal of materials science 16 (1997), S. 626-628 
    ISSN: 1573-4811
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Maschinenbau
    Notizen: Abstract Abstracts are not published in this journal
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 6
    Digitale Medien
    Digitale Medien
    Springer
    Journal of materials science 17 (1998), S. 2067-2069 
    ISSN: 1573-4811
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Maschinenbau
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 7
    ISSN: 1432-0630
    Schlagwort(e): PACS: 81.15.Fg; 61.46.+W; 52.40.Nk
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Maschinenbau , Physik
    Notizen: Abstract. We have developed an integrated process system for the formation of nanoparticles by pulsed laser ablation (PLA) in helium background gas, size classification using a differential mobility analyzer (DMA), and deposition on a substrate. The DMA has been improved to operate at pressures of less than 10 Torr. The classification resolution of the low-pressure operating DMA (LP-DMA), transporting properties of nanoparticles under low pressure, have been investigated theoretically in order to evaluate the performance of the size classification for the integrated system. By operating the integrated system at less than 10 Torr, we have measured the size distribution of Si nanoparticles in the gas phase formation field by sweeping the applied voltage to the LP-DMA and counting the charged nanoparticle concentration with an electrometer. Moreover, we successfully deposited the classified Si nanoparticles on a substrate by fixing the voltage. We have verified that the integrated system can be applied to the clean physical vapor deposition process for accurately size-controlled nanoparticles.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 8
    Digitale Medien
    Digitale Medien
    Springer
    Journal of materials science 15 (1996), S. 544-546 
    ISSN: 1573-4811
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Maschinenbau
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 9
    Digitale Medien
    Digitale Medien
    Springer
    Plasma chemistry and plasma processing 16 (1995), S. S141 
    ISSN: 1572-8986
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Chemie und Pharmazie , Maschinenbau , Technik allgemein
    Notizen: Abstract The prominent features of plasma flash evaporation may be caused by cluster deposition under high net flux of radicals. In order to clarify such features quantitatively, the atomic oxygen flux (Γ o ) and cluster size (d) in 200 Torr RF thermal Ar-O2 plasma were measured on the substrate. It was found that Γ o higher than 1019 atoms/cm2·s can be easily acheived in this processing and this value corresponds to frozen atomic oxygen fraction 7 %. The cluster size of YBCO was estimated to be about 0.3 to 10 nm. 0.8 nm cluster deposition under Γ o higher than 6 × 1018 atoms/cm2·s made it possible to deposit fine epitaxial YBCO films with Tc = 90K on SrTiO3 (100) with extremely high deposition rate around 2.2 μm/min.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 10
    ISSN: 1573-1561
    Schlagwort(e): Picea glehnii ; conifer seedling ; root protection ; Pythium vexans ; associated fungi ; Penicillium spp. ; patulin ; citrinin ; palitantin ; arthrographol
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Chemie und Pharmazie
    Notizen: Abstract We screened the microorganisms that are present on the surface of Picea glehnii seeds and produced antifungal compounds against Pythium vexans, a fungus that causes damping-off. Four isolates of Penicillium species that produced patulin, citrinin, palitantin, and arthrographol, respectively, were identified from 149 different microorganisms screened. This study is the first step in an examination of the ecological interaction between host conifers and fungi located on the surface of their seeds.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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