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  • 1
    Electronic Resource
    Electronic Resource
    Photoconversion of 7-dehydrocholesterol to vitamin D3 in synthetic phospholipid bilayers (1985)
    s.l. : American Chemical Society
    Biochemistry 24 (1985), S. 3338-3344 
    Details
    ISSN: 1520-4995
    Source: ACS Legacy Archives
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/bi00334a039
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  • 2
    Electronic Resource
    Electronic Resource
    Lateral Variations of Lg Coda Q in Southern Mexico (1997)
    Springer
    Pure and applied geophysics 149 (1997), S. 575-599 
    Details
    ISSN: 1420-9136
    Keywords: Key words: Attenuation, coda Q, southern Mexico.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Notes: Abstract —Broad band digital three-component data recorded at UNM, a GEOSCOPE station, were used to estimate Lg coda Q for 34 medium size (3.9 ≤m b ≤ 6.3) earthquakes with travel paths laying in different geological provinces of southern Mexico in an effort to establish the possible existence of geological structures acting as wave guides and/or travel paths of low attenuation between the Pacific coast and the Valley of Mexico. The stacked spectral ratio method proposed by XIE and NUTTLI (1988) was chosen for computing the coda Q. The variation range of Q 0 (Q at 1 Hz) and the frequency dependence parameter η estimates averaged on the frequency interval of 0.5 to 2 Hz for the regions and the three components considered are: i) Guerrero region 173 ≤Q¯ 0≤ 182 and 0.6 ≤Q¯ 0 ≤ 0.7, ii) Oaxaca region 183 ≤Q¯ 0 ≤ 198 and 0.6 ≤Q¯ 0 ≤ 0.8, iii) Michoacan-Jalisco region 187 ≤Q¯ 0 ≤ 204 and 0.7 ≤Q¯ 0 ≤ 0.8 and iv) eastern portion of the Transmexican Volcanic Belt (TMVB) 313 ≤Q 0≤ 335 and η = 0.9. ¶The results show a very high coda Q for the TMVB as compared to other regions of southern Mexico. This unexpected result is difficult to reconcile with the geophysical characteristics of the TMVB, e.g., low seismicity, high volcanic activity and high heat flow typical of a highly attenuating (low Q) region. Visual inspection of seismograms indicates that for earthquakes with seismic waves traveling along the TMVB, the amplitude decay of Lg coda is anomalously slow as compared to other earthquakes in southern Mexico. Thus, it seems that the high Q value found does not entirely reflect the attenuation characteristics of the TMVB but it is probably contaminated by a wave-guide effect. This phenomenon produces an enhancement in the time duration of the Lg wave trains travelling along this geological structure. This result is important to establish the role played by the transmission medium in the extremely long duration of ground motion observed during the September 19, 1985 Michoacan earthquake. ¶The overall spatial distribution of coda Q values indicates that events with focus in the Michoacan-Jalisco and Oaxaca regions yield slightly higher values than those from Guerrero. This feature is more pronounced for the horizontal component of coda Q. A slight dependence of average coda Q −1 on earthquake focal depth is observed in the frequency range of 0.2 to 1.0 Hz approximately on the horizontal component. Deeper (h 〉 50 km) events yield lower values of Q −1 than shallower events. For frequencies higher than 1.0 Hz no clear dependence of Q −1 on focal depth is observed. However, due to the estimates uncertainties this result is not clearly established.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s000240050042
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  • 3
    Electronic Resource
    Electronic Resource
    Distribution of Todarodes pacificus (Cephalopoda: Ommastrephidae) paralarvae near the Kuroshio off southern Kyushu, Japan (1999)
    Springer
    Marine biology 135 (1999), S. 99-106 
    Details
    ISSN: 1432-1793
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The distribution and abundance of Japanese common squid [Todarodes pacificus (Steenstrup, 1880)] paralarvae off southern Kyushu Island near the Kuroshio were examined in relation to water types in the region. Surveys were conducted in 1996 and 1997 using paired, 70 cm diameter Bongo nets. Temperature–salinity plots from 0, 50 and 100 m depths were used to assign sampling stations to three water types: inshore, mixing and Kuroshio. In total, 4103 T. pacificus paralarvae were collected at 59 of 72 stations. Catch densities at positive stations ranged between 8 and 4282 ind./50 m2 sea surface area. Catches during both years were highest in mixing waters, followed by inshore and Kuroshio waters. Total catches were highest just north of the oceanographic front at the inshore edge of the Kuroshio and declined with increasing distance away from the front. Catches of paralarvae ≤1.0 mm mantle length also peaked near the front. In both years, ≥85% of all paralarvae and ≥69% of those ≤1.0 mm mantle length occurred less than 25 km from the front. We conclude that most spawning off southwest Kyushu occurs near the frontal zone, where Kuroshio and inshore waters meet.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002270050606
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  • 4
    Electronic Resource
    Electronic Resource
    Pharmacokinetics of temocapril hydrochloride, a novel angiotensin converting enzyme inhibitor, in renal insufficiency (1992)
    Springer
    European journal of clinical pharmacology 43 (1992), S. 657-659 
    Details
    ISSN: 1432-1041
    Keywords: Temocapril, Renal insufficiency ; angiotensin-I converting enzyme inhibitor, pharmacokinetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The pharmacokinetics of temocapril hydrochloride, a novel prodrug-type angiotensin-I converting enzyme (ACE) inhibitor, has been studied in patients with mild (Group II) to severe (Group III) renal insufficiency in comparison with subjects with normal renal function (Group I). The pharmacokinetic parameters of the active diacid metabolite, including Cmax, AUC and half-life (t1/2), showed only slight changes between the three groups: AUC (0–∞) was significantly larger in Group III than Group I, and t1/2 tended to be prolonged in Group III, but the change was not significant. The urinary recovery of the diacid was significantly decreased in Group III. (Group I, 28.1 %, Group II, 21.6 %, Group III, 12.8 %). Compared with other ACE inhibitors, which are mainly excreted through the kidney, the plasma concentration of the active diacid metabolite was hardly influenced by renal function. It was speculated that lowering of the dose of temocapril might be recommended only in patients with severe renal insufficiency.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02284968
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  • 5
    Electronic Resource
    Electronic Resource
    Screening and identification of yeast sequences that cause growth inhibition when overexpressed (1997)
    Springer
    Molecular genetics and genomics 254 (1997), S. 267-274 
    Details
    ISSN: 1617-4623
    Keywords: Key wordsSaccharomycescerevisiae  ;  Overexpression  ; Growth inhibition  ;  Library screening
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract To isolate genes that negatively regulate cell growth, we constructed a galactose-inducible expression library with partially digested Saccharomyces cerevisiae genomic DNA fragments inserted downstream of the GAL10 promoter. In all, 240 000 yeast transformants were screened for lethality on galactose medium. From 17 such transformants identified, 16 nonoverlapping DNA sequences were obtained. Restriction mapping and determination of DNA sequences adjacent to the GAL10 promoter indicated that the inserts encoded part or all of the URA2, RBP1, TPK3, SAC7, BOI1, and BNI1 genes, and also open reading frames (ORFs) from chromosomes IV, V, IX, XI, and XIII. Some of the identified sequences lacked the amino-terminal sequences of the ORFs, suggesting that truncated forms of the proteins might be necessary for growth inhibition. The sequence of the pGA108 insert was highly homologous to the telomeric X-element and contained an ARS consensus sequence, suggesting a possible growth inhibitory effect of an RNA molecule. Overexpression of the BNI1ΔN and BOI1ΔN genes, which lacked amino-terminal sequences, was associated with phenotypes similar to those of mutants defective in bud formation. Overexpression of the GIN4 and GIN12 sequences induced elongated buds and a G2/M arrest-like phenotype, respectively. The phenotypes induced by the overexpression of our cloned sequences could result from either a dominant-positive or a dominant-negative effect and, unexpectedly, in one case from an effect of an RNA.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004380050415
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  • 6
    Electronic Resource
    Electronic Resource
    Oral and dermal toxicity of organophosphate pesticides in the domestic pigeon (Columba livia) (1994)
    Springer
    Bulletin of environmental contamination and toxicology 52 (1994), S. 633-640 
    Details
    ISSN: 1432-0800
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00195480
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  • 7
    Electronic Resource
    Electronic Resource
    Excretion of intracorporeal cadmium with S-benzoylthiamin monophosphate (1995)
    Springer
    Bulletin of environmental contamination and toxicology 54 (1995), S. 745-750 
    Details
    ISSN: 1432-0800
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00206108
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  • 8
    Electronic Resource
    Electronic Resource
    Exposure Factor and Toxicity Data for California Wildlife: Data Availability and Sources of Uncertainty for Ecological Risk Assessments (2000)
    Springer
    Bulletin of environmental contamination and toxicology 64 (2000), S. 834-841 
    Details
    ISSN: 1432-0800
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s0012800078
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  • 9
    Electronic Resource
    Electronic Resource
    Effects of weak shear on hyperswollen lyotropic smectic liquid crystals (1995)
    Springer
    International journal of thermophysics 16 (1995), S. 1099-1107 
    Details
    ISSN: 1572-9567
    Keywords: liquid crystal ; rheology ; shear effects ; viscometer
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract We have developed a Zimm-type viscometer specially designed for the simultaneous measurements of the structure factor and the viscosity of hyperswollen lyotropic liquid crystals under a very weak shear. We have investigated the shear effects on the layer undulation fluctuation in the lamellar structure and the transition from the anisotropic lamellar to the isotropic sponge phase. We have found a significant difference in the rheological properties between the lamellar and the sponge phase: The former exhibits non-Newtonian flow behavior, while the latter exhibits Newtonian behavior.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02081278
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  • 10
    Electronic Resource
    Electronic Resource
    Large Helical Device (LHD) program (1996)
    Springer
    Journal of fusion energy 15 (1996), S. 7-153 
    Details
    ISSN: 1572-9591
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Notes: Abstract The largest superconducting fusion machine, Large Helical Device (LHD), is now under construction in Japan and will begin operation in 1997. Design and construction of related R&D programs are now being carried out. The major radius of this machine is 3.9 m and the magnetic field on the plasma center is 3 T. The NbTi superconducting conductors are used in both helical coils and poloidal coils to produce this field. This will be upgraded in the second phase a using superfluid coil cooling technique. A negative ion source is being successfully developed for the NBI heating of LHD. This paper describes the present status and progress in its experimental planning and theoretical analysis on LHD, and the design and construction of LHD torus, heating, and diagnostics equipments.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02266926
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