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  • 1
    Electronic Resource
    Electronic Resource
    Preparation and mechanical properties of calcium phosphate/copoly-L-lactide composites (1997)
    Springer
    Journal of materials science 8 (1997), S. 361-364 
    Details
    ISSN: 1573-4838
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Technology
    Notes: Abstract New artificial bone materials were prepared using calcium phosphates, hydroxyapatite and β-tricalicum phosphate, and copoly-L-lactide, CPLA. Calcium phosphate powder and CPLA were mixed at 453 K for 10 min with various mixing ratios. Scanning electron microscope observations indicated that the composites of β-tricalicum phosphate and CPLA were homogeneously dispersed and highly adhesive. Young’s modulus of the composites was the same as bone, and bending strength was over half that of bone. The improvement of Young’s modulus compared to the original two materials was due to a composite effect. The composites are expected to be usable as artificial bone materials.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1018580816388
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Relationship between Ca-Dependent Change of Serum PTHand Extracellular Ca2+-Sensing Receptor Expression in Parathyroid Adenoma (1999)
    Springer
    Calcified tissue international 64 (1999), S. 271-272 
    Details
    ISSN: 1432-0827
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Abnormal PTH secretion and cell growth in hyperparathyroid tissues are accompanied with reduced expression of Ca2+-sensing receptor (CaR) which plays a key role in Ca-regulated PTH release. In this study, we examined the receptor expression in parathyroid adenomas using specific anti-CaR antibody and investigated relationship between CaR expression in adenomatous tissues and parameters of Ca-dependent change of serum PTH. The results show a considerable variation in the number of CaR positive cells among the adenomatous tissues. Expression of the receptor protein was not related to set-point error but was more reduced in the patients with more elevated minimum or baseline levels of serum PTH. CaR expression was severely reduced in the patients with highly elevated maximum serum PTH, while the receptor expression was also decreased in some patients with normal maximum serum PTH. Baseline level / maximum level ratio of serum PTH was increased in these patients. In conclusion, reduced CaR expression is related to abnormality in three parameters of PTH secretion (minimum serum PTH, maximum serum PTH, and baseline level / maximum level ratio of serum PTH) and may contribute to hypersecretion from parathyroid adenomas.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002239900617
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  • 3
    Electronic Resource
    Electronic Resource
    Entrainment of the circadian locomotor activity rhythm in the Japanese newt by melatonin injections (1995)
    Springer
    Journal of comparative physiology 176 (1995), S. 473-477 
    Details
    ISSN: 1432-1351
    Keywords: Circadian rhythms ; Locomotor activity ; Melatonin ; Entrainment ; Newt Cynops pyrrhogaster
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract We examined whether melatonin can act as a synchronizing agent within the circadian system of amphibians by testing the ability of melatonin injections to entrain the circadian locomotor activity rhythm of a newt (Cynops pyrrhogaster). Under constant darkness, all newts (13 cases) showing the free-running rhythms were subcutaneously injected with 10 μg melatonin at the same time every other day for at least 30 days. Subsequently, they were injected with vehicle (1% ethanolic saline) instead of melatonin for at least another 30 days. In 10 of the 13 newts, the locomotor activity rhythms could be entrained to a period of 24 h by melatonin injections but not by vehicle injections. During the entrained steady-state, the active phase of an activity-rest cycle preceded the time of melatonin injections as previously reported in other diurnal species. These results suggest that the endogenous circadian rhythm of melatonin concentration may be involved in synchronizing circadian oscillator(s) within the newt's circadian system.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00196413
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  • 4
    Electronic Resource
    Electronic Resource
    Real-Time Monitoring of Blood–Brain Barrier Disruption Induced by Ultraviolet Laser Irradiation (1998)
    Springer
    Lasers in medical science 13 (1998), S. 172-180 
    Details
    ISSN: 1435-604X
    Keywords: Keywords: Argon laser; Blood–brain barrier; Brain; Evans blue; Guinea-pig; Vasodilation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Physics , Technology
    Notes: Ultraviolet laser light of sufficient power can induce focal œdema in the brain. The formation of ultraviolet-induced vasogenic \kdema was monitored by observing real-time changes in the integrity of the blood–brain barrier. The brain surface of guinea-pigs injected with Evans blue was exposed to light from a continuous wave argon laser at 351 nm, delivered via an optical fibre. The integrity of the blood–brain barrier was evaluated by measuring surface reflectance using a separate probing light. The brain was then sectioned and examined using light and electron microscopy. Extravasation of Evans blue following vasodilatation was observed when the irradiation intensity was greater than 0.64 W/cm2. The extent of glial and vascular damage could be correlated with the laser power. Irradiated vascular endothelium exhibited lipping at the tight junction, vacuolation and mitichondrial swelling. These results suggest that disruption of the blood–brain barrier induced by ultraviolet light is preceded by vasodilatation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s101030050071
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  • 5
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    Magnetic properties of thin gauge 3% Si-Fe with {110}〈001〉 orientation (1995)
    Springer
    Details
    Publication Date: 1995-08-01
    Print ISSN: 1059-9495
    Electronic ISSN: 1544-1024
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Published by Springer
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