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  • Hindawi  (242)
  • Oxford University Press  (208)
  • American Geophysical Union (AGU)
  • 1
    Publication Date: 2022-05-25
    Description: © 2008 The Authors. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License. The definitive version was published in Nucleic Acids Research 37 (2009): D526-D530, doi:10.1093/nar/gkn631.
    Description: GiardiaDB (http://GiardiaDB.org) and TrichDB (http://TrichDB.org) house the genome databases for Giardia lamblia and Trichomonas vaginalis, respectively, and represent the latest additions to the EuPathDB (http://EuPathDB.org) family of functional genomic databases. GiardiaDB and TrichDB employ the same framework as other EuPathDB sites (CryptoDB, PlasmoDB and ToxoDB), supporting fully integrated and searchable databases. Genomic-scale data available via these resources may be queried based on BLAST searches, annotation keywords and gene ID searches, GO terms, sequence motifs and other protein characteristics. Functional queries may also be formulated, based on transcript and protein expression data from a variety of platforms. Phylogenetic relationships may also be interrogated. The ability to combine the results from independent queries, and to store queries and query results for future use facilitates complex, genome-wide mining of functional genomic data.
    Description: Federal funds from the National Institute of Allergy and Infectious Diseases; Department of Health and Human Services, National Institutes of Health (HHSN266200400037C). Funding for open access charge: National Institutes of Health (HHSN266200400037C).
    Repository Name: Woods Hole Open Access Server
    Type: Article
    Format: application/pdf
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  • 2
    Publication Date: 2020-08-25
    Description: Natural polyphenols contained in olive mill wastewaters (OMW) have been usually associated with great bioactive properties as “antioxidants”. In this work, we recovered the polyphenols after adsorption onto natural clay “ghassoul” by different solvents: water, ethyl acetate, and methanol (PPW, PPA, and PPM, respectively) to avoid environmental pollution. Also, we tested the antioxidant activity of the extracted polyphenols by two methods: 1,1-diphenyl-2-picrylhydrazyl (DPPH) and total antioxidant capacity (TAC). Then, we analyzed antimicrobial activity by the microdilution technique to determine at the minimum inhibitory concentration (MIC) and the minimum bactericidal concentration (MBC). The OMW of the Fez-Meknes region has a very acidic pH, considerable amounts of mineral matter, and a high concentration of polyphenols and organic content. The results of the test from DPPH showed good antiradical potential for polyphenols extracted with water, but the TAC showed an important capacity for all extracts unless PPA. The antibacterial activity is not the same on the four bacteria studied (Escherichia coli, Salmonella sp, Staphylococcus aureus, and Enterococcus faecalis), and all extracts inhibit most tested germs that do not have the same MIC and the same sensitivity. Only the PPW showed the minimum bactericidal concentration (MBC) that is equal to 0.290 mg/mL for Salmonella sp and Staphylococcus aureus, which confirms that the extraction by water of the adsorbed polyphenols is an original solution to recover the polyphenols and also to obtain a natural phenolic antioxidant which can be used in the pharmaceutical, nourishment, and cosmetic industry.
    Print ISSN: 2090-9063
    Electronic ISSN: 2090-9071
    Topics: Chemistry and Pharmacology
    Published by Hindawi
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  • 3
    Publication Date: 2020-07-14
    Description: With the advancement in ICT, web search engines have become a preferred source to find health-related information published over the Internet. Google alone receives more than one billion health-related queries on a daily basis. However, in order to provide the results most relevant to the user, WSEs maintain the users’ profiles. These profiles may contain private and sensitive information such as the user’s health condition, disease status, and others. Health-related queries contain privacy-sensitive information that may infringe user’s privacy, as the identity of a user is exposed and may be misused by the WSE and third parties. This raises serious concerns since the identity of a user is exposed and may be misused by third parties. One well-known solution to preserve privacy involves issuing the queries via peer-to-peer private information retrieval protocol, such as useless user profile (UUP), thereby hiding the user’s identity from the WSE. This paper investigates the level of protection offered by UUP. For this purpose, we present QuPiD (query profile distance) attack: a machine learning-based attack that evaluates the effectiveness of UUP in privacy protection. QuPiD attack determines the distance between the user’s profile (web search history) and upcoming query using our proposed novel feature vector. The experiments were conducted using ten classification algorithms belonging to the tree-based, rule-based, lazy learner, metaheuristic, and Bayesian families for the sake of comparison. Furthermore, two subsets of an America Online dataset (noisy and clean datasets) were used for experimentation. The results show that the proposed QuPiD attack associates more than 70% queries to the correct user with a precision of over 72% for the clean dataset, while for the noisy dataset, the proposed QuPiD attack associates more than 40% queries to the correct user with 70% precision.
    Print ISSN: 1058-9244
    Electronic ISSN: 1875-919X
    Topics: Computer Science , Media Resources and Communication Sciences, Journalism
    Published by Hindawi
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  • 4
    Publication Date: 2020-07-11
    Description: Magnetically separable strontium hexaferrite SrFe12O19 was prepared using the chemical coprecipitation method, and the nanostructured material was characterized by X-ray diffraction, scanning electron microscopy (SEM), energy-dispersive spectrometry (EDS), and BET analysis. The SEM images showed the homogeneity of the chemical composition of SrFe12O19 and uniform distribution of size and morphology. The pore size of the nanomaterial and its specific area were determined by BET measurements. Strontium hexaferrite SrFe12O19 exhibited a strong magnetic field, which is highly suitable in the heterogeneous catalysis as it can be efficiently separated from the reaction. The magnetic nanocatalyst showed high activity and environmentally benign heterogeneous catalysts for the epoxide ring-opening with amines affording β-amino alcohols under solvent-free conditions. When unsymmetrical epoxides were treated in the presence of aromatics amines, the regioselectivity was influenced by the electronic and steric factors. Total regioselectivity was observed for the reactions performed with aliphatic amines. The magnetically SrFe12O19 nanocatalyst showed excellent recyclability with continuously good catalytic activities after four cycles.
    Print ISSN: 2090-9063
    Electronic ISSN: 2090-9071
    Topics: Chemistry and Pharmacology
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  • 5
    Publication Date: 2020-07-02
    Description: In this paper, we present a mathematical model that describes agree-disagree opinions during polls. We first present the different compartments of the model. Then, using the next-generation matrix method, we derive thresholds of the stability of equilibria. We consider two sets of data from the Reuters polling system regarding the approval rating of the U.S presidential in two terms. These two weekly polls data track the percentage of Americans who approve and disapprove of the way the President manages his work. To validate the reality of the underlying model, we use nonlinear least-squares regression to fit the model to actual data. In the first poll, we consider only 31 weeks to estimate the parameters of the model, and then, we compare the rest of the data with the outcome of the model over the remaining 21 weeks. We show that our model fits correctly the real data. The second poll data is collected for 115 weeks. We estimate again the parameters of the model, and we show that our model can predict the poll outcome in the next weeks, thus, whether the need for some control strategies or not. Finally, we also perform several computational and statistical experiments to validate the proposed model in this paper. To study the influence of various parameters on these thresholds and to identify the most influential parameters, sensitivity analysis is carried out to investigate the effect of the small perturbation near a parameter value on the value of the threshold. An uncertainty analysis is performed to evaluate the forecast inaccuracy in the outcome variable due to uncertainty in the estimation of the parameters.
    Print ISSN: 1085-3375
    Electronic ISSN: 1687-0409
    Topics: Mathematics
    Published by Hindawi
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  • 6
    Publication Date: 2015-09-21
    Description: This paper presents the simulation of a two-rotor aircraft in different geometric configurations during hover flight. The analysis was performed using an implementation of the unsteady vortex-lattice method (UVLM). A description of the UVLM is presented as well as the techniques used to enhance the stability of results for rotors in hover flight. The model is validated for an isolated rotor in hover, comparing numerical results to experimental data (high-Reynolds, low-Mach conditions). Results show that an exclusion of the root vortex generates a more stable wake, without affecting results. Results for the two-rotor aircraft show an important influence of the number of blades on the vertical thrust. Furthermore, the geometric configuration has a considerable influence on the pitching moment.
    Print ISSN: 1024-123X
    Electronic ISSN: 1563-5147
    Topics: Mathematics , Technology
    Published by Hindawi
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  • 7
    Publication Date: 2015-06-02
    Description: The reproducing kernel algorithm is described in order to obtain the efficient analytical-numerical solutions to nonlinear systems of two point, second-order periodic boundary value problems with finitely many singularities. The analytical-numerical solutions are obtained in the form of an infinite convergent series for appropriate periodic boundary conditions in the space , whilst two smooth reproducing kernel functions are used throughout the evolution of the algorithm to obtain the required nodal values. An efficient computational algorithm is provided to guarantee the procedure and to confirm the performance of the proposed approach. The main characteristic feature of the utilized algorithm is that the global approximation can be established on the whole solution domain, in contrast with other numerical methods like onestep and multistep methods, and the convergence is uniform. Two numerical experiments are carried out to verify the mathematical results, whereas the theoretical statements for the solutions are supported by the results of numerical experiments. Our results reveal that the present algorithm is a very effective and straightforward way of formulating the analytical-numerical solutions for such nonlinear periodic singular systems.
    Print ISSN: 1024-123X
    Electronic ISSN: 1563-5147
    Topics: Mathematics , Technology
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  • 8
    Publication Date: 2015-05-19
    Description: The combination of DNA bisulfite treatment with high-throughput sequencing technologies has enabled investigation of genome-wide DNA methylation beyond CpG sites and CpG islands. These technologies have opened new avenues to understand the interplay between epigenetic events, chromatin plasticity and gene regulation. However, the processing, managing and mining of this huge volume of data require specialized computational tools and statistical methods that are yet to be standardized. Here, we describe a complete bisulfite sequencing analysis workflow, including recently developed programs, highlighting each of the crucial analysis steps required, i.e. sequencing quality control, reads alignment, methylation scoring, methylation heterogeneity assessment, genomic features annotation, data visualization and determination of differentially methylated cytosines. Moreover, we discuss the limitations of these technologies and considerations to perform suitable analyses.
    Print ISSN: 1467-5463
    Electronic ISSN: 1477-4054
    Topics: Biology , Computer Science
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  • 9
    Publication Date: 2016-07-31
    Description: The Hα and optical broad-band images of 25 nearby Wolf–Rayet (WR) galaxies are presented. The WR galaxies are known to have a recent (≤10 Myr) and massive star formation episode. The photometric Hα fluxes are estimated and corrected for extinction and line contamination in the filter pass-bands. The star formation rates (SFRs) are estimated using Hα images and from archival data in the far-ultraviolet (FUV), far-infrared (FIR) and 1.4-GHz radio continuum wavebands. A comparison of SFRs estimated from different wavebands is made after including similar data available in the literature for other WR galaxies. The Hα-based SFRs are found to be tightly correlated with SFRs estimated from the FUV data. The correlations also exist with SFR estimates based on the radio and FIR data. The WR galaxies also follow the radio–FIR correlation known for normal star-forming galaxies, although it is seen here that the majority of dwarf WR galaxies have a radio deficiency. An analysis using the ratio of non-thermal to thermal radio continuum and the ratio of the FUV to Hα SFRs indicates that WR galaxies have lower non-thermal radio emission compared to normal galaxies, most likely due to a lack of supernovae in the very young star formation episode in the WR galaxies. The morphologies of 16 galaxies in our sample are highly suggestive of an ongoing tidal interaction or a past merger in these galaxies. This survey strengthens the conclusions obtained from previous similar studies indicating the importance of tidal interactions in triggering star-formation in WR galaxies.
    Print ISSN: 0035-8711
    Electronic ISSN: 1365-2966
    Topics: Physics
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  • 10
    Publication Date: 2016-07-26
    Description: This work aims to present the modification of polypropylene (PP) membranes using three different biopolymers, chitosan (CHI), potato starch (PS), and cellulose (CEL), in order to obtain three new materials. The modified membranes may be degraded easier than polypropylene ones and could be used as selective membranes for metal ions removal, among other applications. For this purpose, the UV energy induced graft copolymerization reaction among polypropylene membrane, acrylic acid, benzophenone (as photoinitiator), and the biopolymer (CHI, PS, or CEL) was conducted. The results of FT-IR-ATR, XRD, TGA, DSC, SEM, BET, and AFM analyses and mechanical properties clearly indicate the successful modification of the membrane surface. The change of surface wettability was monitored by contact angle. The grafting reaction depends on natural polymer, reaction time, and concentration. In order to prove the potential application of the modified membranes, a preliminary study of sorption of metal ion was carried out. For this purpose, the PP-CHI membrane was chosen because of the high hydrophilicity, proportionate to -OH and NH2; these groups could act as ligands of metal ions, provoking the interaction between PP-CHI and M+ (PP-CHI-M+) and therefore the metal ion removal from water.
    Print ISSN: 2090-9063
    Topics: Chemistry and Pharmacology
    Published by Hindawi
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