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  • Oxford University Press  (187)
  • Blackwell Publishers Ltd
  • 1
    Publication Date: 2020-09-29
    Description: The knowledge of the genetic variability of the local population is of utmost importance in personalized medicine and has been revealed as a critical factor for the discovery of new disease variants. Here, we present the Collaborative Spanish Variability Server (CSVS), which currently contains more than 2000 genomes and exomes of unrelated Spanish individuals. This database has been generated in a collaborative crowdsourcing effort collecting sequencing data produced by local genomic projects and for other purposes. Sequences have been grouped by ICD10 upper categories. A web interface allows querying the database removing one or more ICD10 categories. In this way, aggregated counts of allele frequencies of the pseudo-control Spanish population can be obtained for diseases belonging to the category removed. Interestingly, in addition to pseudo-control studies, some population studies can be made, as, for example, prevalence of pharmacogenomic variants, etc. In addition, this genomic data has been used to define the first Spanish Genome Reference Panel (SGRP1.0) for imputation. This is the first local repository of variability entirely produced by a crowdsourcing effort and constitutes an example for future initiatives to characterize local variability worldwide. CSVS is also part of the GA4GH Beacon network. CSVS can be accessed at: http://csvs.babelomics.org/.
    Print ISSN: 0305-1048
    Electronic ISSN: 1362-4962
    Topics: Biology
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK and Boston, USA : Blackwell Publishers Ltd
    Labour 11 (1997), S. 0 
    ISSN: 1467-9914
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Economics
    Notes: Spain is one of the southern countries where the percentage of women working part-time is relatively low in comparison to other European countries, together with a low female activity rate. Some important obstacles to increasing female activity rates have already been removed, as younger cohorts of women show a more permanent attachment to the labour force than older women, meeting even high unemployment, which is especially acute for women and young people. Under the recent labour market reform, it is hoped that part-time contracts, which were first regulated in 1984, would be a way of facilitating flexibility and an incentive for employers to create jobs, as the experience of other countries has shown. The relative novelty of part-time work in Spain is the reason why this typically female employment regime has not been much explored in Spain yet, in spite of its important role in the reorganisation of the employment system.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK and Boston, USA : Blackwell Publishers Ltd
    Labour 14 (2000), S. 0 
    ISSN: 1467-9914
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Economics
    Notes: Spain has one of the highest rates of unemployment among OECD countries. Some explanations for this stress the importance of unemployment duration compared with entry rates to the unemployment pool. Long-term unemployment rates are particularly high among women in Spain. The object of this paper is to investigate the determinants of unemployment duration among women. It will consider personal characteristics (education and age), family background, socio-economic variables (the number of household earners and household income) and the effect of unemployment benefits, using data from the Household Expenditure Survey 1990–91.
    Type of Medium: Electronic Resource
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  • 4
    Publication Date: 2015-08-25
    Description: We investigate the star formation properties of ~800 sources detected in one of the deepest radio surveys at 1.4 GHz. Our sample spans a wide redshift range (~0.1–4) and about four orders of magnitude in star formation rate (SFR). It includes both star-forming galaxies (SFGs) and active galactic nuclei (AGNs), further divided into radio-quiet (RQ) and radio-loud objects. We compare the SFR derived from the far-infrared luminosity, as traced by Herschel , with the SFR computed from their radio emission. We find that the radio power is a good SFR tracer not only for pure SFGs but also in the host galaxies of RQ AGNs, with no significant deviation with redshift or specific SFR. Moreover, we quantify the contribution of the starburst activity in the SFG population and the occurrence of AGNs in sources with different level of star formation. Finally, we discuss the possibility of using deep radio survey as a tool to study the cosmic star formation history.
    Print ISSN: 0035-8711
    Electronic ISSN: 1365-2966
    Topics: Physics
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  • 5
    Publication Date: 2015-08-27
    Description: Using deep Herschel and ALMA observations, we investigate the star formation rate (SFR) distributions of X-ray-selected active galactic nucleus (AGN) host galaxies at 0.5 〈  z  〈 1.5 and 1.5 〈  z  〈 4, comparing them to that of normal, star-forming (i.e. ‘main-sequence’, or MS) galaxies. We find that 34–55 per cent of AGNs in our sample have SFRs at least a factor of 2 below that of the average MS galaxy, compared to 15 per cent of all MS galaxies, suggesting significantly different SFR distributions. Indeed, when both are modelled as lognormal distributions, the mass and redshift-normalized SFR distributions of X-ray AGNs are roughly twice as broad, and peak 0.4 dex lower, than that of MS galaxies. However, like MS galaxies, the normalized SFR distribution of AGNs in our sample appears not to evolve with redshift. Despite X-ray AGNs and MS galaxies having different SFR distributions, the linear-mean SFR of AGNs derived from our distributions is remarkably consistent with that of MS galaxies, and thus with previous results derived from stacked Herschel data. This apparent contradiction is due to the linear-mean SFR being biased by bright outliers, and thus does not necessarily represent a true characterization of the typical SFR of X-ray AGNs.
    Print ISSN: 1745-3925
    Electronic ISSN: 1745-3933
    Topics: Physics
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  • 6
    Publication Date: 2016-07-15
    Description: We exploit Atacama Large Interferometer Array (ALMA) 870 μm observations to measure the star formation rates (SFRs) of eight X-ray detected active galactic nuclei (AGNs) in a z 3.1 protocluster, four of which reside in extended Lyα haloes (often termed Lyman-alpha blobs: LABs). Three of the AGNs are detected by ALMA and have implied SFRs of 220–410 M  yr –1 ; the non-detection of the other five AGNs places SFR upper limits of 210 M  yr –1 . The mean SFR of the protocluster AGNs (110–210 M  yr –1 ) is consistent (within a factor of 0.7–2.3) with that found for co-eval AGNs in the field, implying that the galaxy growth is not significantly accelerated in these systems. However, when also considering ALMA data from the literature, we find evidence for elevated mean SFRs (up-to a factor of 5.9 over the field) for AGNs at the protocluster core, indicating that galaxy growth is significantly accelerated in the central regions of the protocluster. We also show that all of the four protocluster LABs are associated with an ALMA counterpart within the extent of their Lyα emission. The SFRs of the ALMA sources within the LABs (150–410 M  yr –1 ) are consistent with those expected for co-eval massive star-forming galaxies in the field. Furthermore, the two giant LABs (with physical extents of 100 kpc) do not host more luminous star formation than the smaller LABs, despite being an order of magnitude brighter in Lyα emission. We use these results to discuss star formation as the power source of LABs.
    Print ISSN: 0035-8711
    Electronic ISSN: 1365-2966
    Topics: Physics
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  • 7
    Publication Date: 2016-03-24
    Description: We present the results from a study of the morphologies of moderate luminosity X-ray-selected active galactic nuclei (AGN) host galaxies in comparison to a carefully mass-matched control sample at 0.5 〈 z 〈 3 in the CANDELS GOODS-S field. We apply a multiwavelength morphological decomposition analysis to these two samples and report on the differences between the morphologies as fitted from single Sérsic and multiple Sérsic models, and models which include an additional nuclear point-source component. Thus, we are able to compare the widely adopted single Sérsic fits from previous studies to the results from a full morphological decomposition, and address the issue of how biased the inferred properties of AGN hosts are by a potential nuclear contribution from the AGN itself. We find that the AGN hosts are indistinguishable from the general galaxy population except that beyond z ~= 1.5 they have significantly higher bulge fractions. Even including nuclear sources in our modelling, the probability of this result arising by chance is ~1 x 10 –5 , alleviating concerns that previous, purely single Sérsic, analyses of AGN hosts could have been spuriously biased towards higher bulge fractions. This data set also allows us to further probe the physical nature of these point-source components; we find no strong correlation between the point-source component and AGN activity. Our analysis of the bulge and disc fractions of these AGN hosts in comparison to a mass-matched control sample reveals a similar morphological evolutionary track for both the active and non-active populations, providing further evidence in favour of a model where AGN activity is triggered by secular processes.
    Print ISSN: 0035-8711
    Electronic ISSN: 1365-2966
    Topics: Physics
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  • 8
    Publication Date: 2016-02-20
    Description: Using artificial neural network predictions of total infrared luminosities (L IR ), we compare the host galaxy star formation rates (SFRs) of ~21 000 optically selected active galactic nuclei (AGN), 466 low-excitation radio galaxies (LERGs) and 721 mid-IR-selected AGN. SFR offsets (SFR) relative to a sample of star-forming ‘main-sequence’ galaxies (matched in M * , z and local environment) are computed for the AGN hosts. Optically selected AGN exhibit a wide range of SFR, with a distribution skewed to low SFRs and a median SFR = –0.06 dex. The LERGs have SFRs that are shifted to even lower values with a median SFR = –0.5 dex. In contrast, mid-IR-selected AGN have, on average, SFRs enhanced by a factor of ~1.5. We interpret the different distributions of SFR amongst the different AGN classes in the context of the relative contribution of triggering by galaxy mergers. Whereas the LERGs are predominantly fuelled through low accretion rate secular processes which are not accompanied by enhancements in SFR, mergers, which can simultaneously boost SFRs, most frequently lead to powerful, obscured AGN.
    Print ISSN: 1745-3925
    Electronic ISSN: 1745-3933
    Topics: Physics
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  • 9
    Publication Date: 2016-02-03
    Description: We present high-resolution (0.3 arcsec) Atacama Large Millimeter Array (ALMA) 870 μm imaging of five z 1.5–4.5 X-ray detected AGN (with luminosities of L 2–8keV 〉 10 42  erg s –1 ). These data provide a 20 times improvement in spatial resolution over single-dish rest-frame far-infrared (FIR) measurements. The sub-millimetre emission is extended on scales of FWHM  0.2 arcsec–0.5 arcsec, corresponding to physical sizes of 1–3 kpc (median value of 1.8 kpc). These sizes are comparable to the majority of z =1–5 sub-millimetre galaxies (SMGs) with equivalent ALMA measurements. In combination with spectral energy distribution analyses, we attribute this rest-frame FIR emission to dust heated by star formation. The implied star-formation rate surface densities are 20–200 M  yr –1  kpc –2 , which are consistent with SMGs of comparable FIR luminosities (i.e. L IR  [1–5] x 10 12  L ). Although limited by a small sample of AGN, which all have high-FIR luminosities, our study suggests that the kpc-scale spatial distribution and surface density of star formation in high-redshift star-forming galaxies is the same irrespective of the presence of X-ray detected AGN.
    Print ISSN: 1745-3925
    Electronic ISSN: 1745-3933
    Topics: Physics
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  • 10
    Publication Date: 2014-05-06
    Description: We have investigated the gas content of a sample of several hundred AGN host galaxies at z  〈 1 and compared it with a sample of inactive galaxies, matched in bins of stellar mass and redshift. Gas masses have been inferred from the dust masses, obtained by stacked Herschel far-IR and sub-mm data in the GOODS and COSMOS fields, under reasonable assumptions and metallicity scaling relations for the dust-to-gas ratio. We find that AGNs are on average hosted in galaxies much more gas rich than inactive galaxies. In the vast majority of stellar mass bins, the average gas content of AGN hosts is higher than that in inactive galaxies. The difference is up to a factor of 10 higher in low-stellar-mass galaxies, with a significance of 6.5. In almost half of the AGN sample, the gas content is three times higher than that in the control sample of inactive galaxies. Our result strongly suggests that the probability of having an AGN activated is simply driven by the amount of gas in the host galaxy; this can be explained in simple terms of statistical probability of having a gas cloud falling into the gravitational potential of the black hole. The increased probability of an AGN being hosted by a star-forming galaxy, identified by previous works, may be a consequence of the relationship between gas content and AGN activity, found in this paper, combined with the Schmidt–Kennicutt law for star formation.
    Print ISSN: 0035-8711
    Electronic ISSN: 1365-2966
    Topics: Physics
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