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  • 1
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    The Gospel according to John : a literary and theological commentary (2000)
    New York : Oxford University Press
    Details
    Keywords: Bible., N.T., John. ; Bible., N.T., John, Commentaries.
    Pages: xiii, 625 p.
    Edition: Pbk. rpt. ed., 1997
    ISBN: 0-585-27829-6
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=23535
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    E-Book (German National Licenses)
  • 2
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    An Empirical Study of the Relationship between Seasonal Precipitation and Thermodynamic Environment in Puerto Rico (2019)
    American Meteorological Society (AMS)
    Details
    Publication Date: 2019
    Description: Weather and Forecasting, Volume 34, Issue 2, Page 277-288, April 2019. 〈br/〉
    Print ISSN: 0882-8156
    Topics: Geography , Physics
    Published by American Meteorological Society (AMS)
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  • 3
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    Cloud-to-Ground Lightning Flash Density and Thunderstorm Day Distributions over the Contiguous United States Derived from NLDN Measurements: 1993-2018 (2019)
    American Meteorological Society (AMS)
    Details
    Publication Date: 2019
    Description: Monthly Weather Review, Ahead of Print. 〈br/〉
    Print ISSN: 0027-0644
    Electronic ISSN: 1520-0493
    Topics: Geography , Geosciences , Physics
    Published by American Meteorological Society (AMS)
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  • 4
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    Investigation of lysine side chain interactions of interleukin-8 with heparin and other glycosaminoglycans studied by a methylation-NMR approach (2013)
    Oxford University Press
    Details
    Publication Date: 2013-10-15
    Description: Although the interaction between interleukin-8 (IL-8) and glycosaminoglycans (GAGs) is crucial for the mediation of inflammatory effects, little is known about the site specificity of this interaction. Therefore, we studied complexes of IL-8 and heparin (HEP) as well as other GAGs in a multidisciplinary approach, involving site-directed mutagenesis, mass spectrometry, fluorescence and solution NMR spectroscopy as well as computer modeling. The interaction between GAG and IL-8 is largely driven by the amine groups of the lysine and the guanidinium groups of arginine side chains. However, due to fast exchange with the solvent, it is typically not possible to detect NMR signals of those groups. Here, we applied reductive 13 C-methylation of the lysine side chains providing sensitive NMR probes for monitoring directly the sites of GAG interaction in 1 H- 13 C correlation experiments. We focused on the lysine side chains K25, K28, K59, K69 and K72 of IL-8 (1–77), which were reported to be involved in the binding to GAGs. The NMR signals of these residues were assigned in 1 H- 13 C HSQC spectra through the help of site-directed mutagenesis. NMR and fluorescence titration experiments in combination with molecular docking and molecular dynamics simulations were applied to investigate the involvement of each lysine in the binding with HEP and various GAG hexasaccharides. We identified K25, K69 and K72 to be the most relevant binding anchors of IL-8(1–77) for the analyzed GAGs.
    Print ISSN: 0959-6658
    Electronic ISSN: 1460-2423
    Topics: Biology , Medicine
    Published by Oxford University Press
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  • 5
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    Processes and Timescales of Magma Genesis and Differentiation Leading to the Great Tambora Eruption in 1815 (2012)
    Oxford University Press
    Details
    Publication Date: 2012-01-18
    Description: The cataclysmic eruption of Tambora volcano (Sumbawa, Indonesia) in 1815 has long been recognized as one of the largest explosive eruptions in historical time. It yielded extensive pyroclastic deposits from the emptying of a 30–33 km 3 trachyandesite (latite)–tephriphonolite (herein referred to as trachyandesite) magma body. The parental trachybasalt magma of the trachyandesite erupted in 1815 can be produced by ~2% partial melting of a garnet-free, Indian-type mid-ocean ridge basalt (I-MORB)-like mantle source contaminated with ~3% fluids from altered oceanic crust and 〈1% sedimentary material, preserving small 238 U excesses in the Tambora rocks. Magmatic differentiation from primary trachybasalt to trachyandesite occurred during two-stage, polybaric differentiation at depth(s) around the Moho and in a shallow-level crustal magma reservoir, emplaced at a maximum depth of ~7·5 km (and, possibly, as shallow as ~2·3 km). This crustal reservoir grew by influx of basaltic trachyandesite (shoshonite) magma, which originated predominantly by partial crystallization of primary trachybasalt in the inferred deep reservoir. Subsequent magmatic differentiation dominated by fractional crystallization, magma recharge–mixing and convection over timescales of ~4000–4500 years led to the trachyandesitic (and ultimately phonolitic) melts erupted in 1815. Highly calcic, corroded plagioclase crystals in 226 Ra– 230 Th equilibrium (〉8000 years old) provide physical evidence for incorporation of ‘antecrystic’ material into the 1815 magma. Magma accumulation and differentiation at shallow depth prior to the eruption were accompanied by continuous degassing of sulphur (and other volatile species), which is thought not to have accumulated within or towards the top of the magma reservoir to contribute to the volatile budget of the eruption, but to have escaped to the surface passively through the permeable wall rocks.
    Print ISSN: 0022-3530
    Electronic ISSN: 1460-2415
    Topics: Geosciences
    Published by Oxford University Press
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  • 6
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    Circular RNAs are depleted of polymorphisms at microRNA binding sites (2014)
    Oxford University Press
    Details
    Publication Date: 2014-08-06
    Description: Motivation: Circular RNAs (circRNAs) are an abundant class of highly stable RNAs that can affect gene regulation by binding and preventing microRNAs (miRNAs) from regulating their messenger RNA (mRNA) targets. Mammals have thousands of circRNAs with predicted miRNA binding sites, but only two circRNAs have been verified as being actual miRNA sponges. As it is unclear whether these thousands of predicted miRNA binding sites are functional, we investigated whether miRNA seed sites within human circRNAs are under selective pressure. Results: Using SNP data from the 1000 Genomes Project, we found a significant decrease in SNP density at miRNA seed sites compared with flanking sequences and random sites. This decrease was similar to that of miRNA seed sites in 3' untranslated regions, suggesting that many of the predicted miRNA binding sites in circRNAs are functional and under similar selective pressure as miRNA binding sites in mRNAs. Contact: pal.satrom@ntnu.no Supplementary information: Supplementary data are available at Bioinformatics online.
    Print ISSN: 1367-4803
    Electronic ISSN: 1460-2059
    Topics: Biology , Computer Science , Medicine
    Published by Oxford University Press
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  • 7
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    The valuation criterion for normal basis generators (2012)
    Oxford University Press
    Details
    Publication Date: 2012-07-14
    Description: If L / K is a finite Galois extension of local fields, then we say that the valuation criterion VC( L / K ) holds if there is an integer d such that every element x L with valuation d generates a normal basis for L / K . Answering a question of Byott and Elder, we first prove that VC( L / K ) holds if and only if the tamely ramified part of the extension L / K is trivial and every non-zero K [ G ]-submodule of L contains a unit of the valuation ring of L . Moreover, the integer d can take one value modulo [ L : K ] only, namely– d L / K –1, where d L / K is the valuation of the different of L / K . When K has positive characteristic, we thus recover a recent result of Elder and Thomas, proving that VC( L / K ) is valid for all extensions L / K in this context. When char  K =0, we identify all abelian extensions L / K for which VC( L / K ) is true, using algebraic arguments. These extensions are determined by the behaviour of their cyclic Kummer subextensions.
    Print ISSN: 0024-6093
    Electronic ISSN: 1469-2120
    Topics: Mathematics
    Published by Oxford University Press
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  • 8
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    Evidence for density-dependent changes in body condition and pregnancy rate of North Atlantic fin whales over four decades of varying environmental conditions (2013)
    Oxford University Press
    Details
    Publication Date: 2013-08-22
    Description: Williams, R., Vikingsson, G. A., Gislason, A., Lockyer, C., New, L., Thomas, L., and Hammond, P. S. 2013. Evidence for density-dependent changes in body condition and pregnancy rate of North Atlantic fin whales over four decades of varying environmental conditions. – ICES Journal of Marine Science, 70: 1273–1280. A central theme in ecology is the search for pattern in the response of a species to changing environmental conditions. Natural resource management and endangered species conservation require an understanding of density-dependent and density-independent factors that regulate populations. Marine mammal populations are expected to express density dependence in the same way as terrestrial mammals, but logistical difficulties in data acquisition for many large whale species have hindered attempts to identify population-regulation mechanisms. We explored relationships between body condition (inferred from patterns in blubber thickness) and per capita prey abundance, and between pregnancy rate and body condition in North Atlantic fin whales as environmental conditions and population size varied between 1967 and 2010. Blubber thickness in both males and females declined at low per capita prey availability, and in breeding-age females, pregnancy rate declined at low blubber thickness, demonstrating a density-dependent response of pregnancy to prey limitation mediated through body condition. To the best of our knowledge, this is the first time a quantitative relationship among per capita prey abundance, body condition, and pregnancy rate has been documented for whales. As long-lived predators, marine mammals can act as indicators of the state of marine ecosystems. Improving our understanding of the relationships that link prey, body condition, and population parameters such as pregnancy rate and survival will become increasingly useful as these systems are affected by natural and anthropogenic change. Quantifying linkages among prey, fitness and vital rates will improve our ability to predict population consequences of subtle, sublethal impacts of ocean noise and other anthropogenic stressors.
    Print ISSN: 1054-3139
    Electronic ISSN: 1095-9289
    Topics: Biology , Geosciences , Physics
    Published by Oxford University Press
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  • 9
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    Models for predicting the within-tree and regional variation of tracheid length and width for plantation loblolly pine (2020)
    Oxford University Press
    Details
    Publication Date: 2020-06-03
    Description: Loblolly pine is a major fibre source for the pulp and paper industry. Here we developed the first nonlinear models to predict the within-tree and regional variation of tracheid length and width for planted loblolly pine. Data were obtained from macerated tracheids and near-infrared spectroscopy calibration models from trees sampled in 109 stands across the southeastern United States. The fixed effects for the final tracheid length model, which included cambial age, height of disk within tree, and physiographic region, explained 71 percent of the variation with root mean square error (RMSE) of 0.28 mm, while the fixed effects for the final tracheid width model explained 57 percent of the variation with RMSE of 1.4 μm. There was significant variation in tracheid properties across the growing regions. Tree maps showing within-tree variability in tracheid properties were produced. Five simulated scenarios were compared using the models developed, with mean tracheid dimensions calculated on a whole-tree basis at a first and second thinnings, and at final harvest. Also from the final harvest, the tops of trees, and outerwood chips produced during lumber manufacturing were also simulated. For the whole tree scenarios, both mean tracheid length and width increased with age, increasing from 2.24 mm and 40.5 μm (age 12), to 2.51 mm and 41.3 μm (age 18), and to 2.73 and 41.8 μm at age 25, respectively. The tops of the trees at age 25 had a mean tracheid length of 2.46 mm and a mean width of 41.0 μm, while the chips had a mean tracheid length of 3.13 mm and a mean width of 42.5 μm. Due to the models representing samples collected from across the southeastern United States, and their relatively high precision, they are suitable for incorporation into growth and yield systems allowing for prediction of tracheid properties.
    Print ISSN: 0015-752X
    Electronic ISSN: 1464-3626
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Published by Oxford University Press
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  • 10
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    Characterizing uncertainty in climate impact projections: a case study with seven marine species on the North American continental shelf (2020)
    Oxford University Press
    Details
    Publication Date: 2020-08-08
    Description: Projections of climate change impacts on living resources are being conducted frequently, and the goal is often to inform policy. Species projections will be more useful if uncertainty is effectively quantified. However, few studies have comprehensively characterized the projection uncertainty arising from greenhouse gas scenarios, Earth system models (ESMs), and both structural and parameter uncertainty in species distribution modelling. Here, we conducted 8964 unique 21st century projections for shifts in suitable habitat for seven economically important marine species including American lobster, Pacific halibut, Pacific ocean perch, and summer flounder. For all species, both the ESM used to simulate future temperatures and the niche modelling approach used to represent species distributions were important sources of uncertainty, while variation associated with parameter values in niche models was minor. Greenhouse gas emissions scenario contributed to uncertainty for projections at the century scale. The characteristics of projection uncertainty differed among species and also varied spatially, which underscores the need for improved multi-model approaches with a suite of ESMs and niche models forming the basis for uncertainty around projected impacts. Ensemble projections show the potential for major shifts in future distributions. Therefore, rigorous future projections are important for informing climate adaptation efforts.
    Print ISSN: 1054-3139
    Electronic ISSN: 1095-9289
    Topics: Biology , Geosciences , Physics
    Published by Oxford University Press on behalf of International Council for the Exploration of the Sea.
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