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  • 1
    Electronic Resource
    Electronic Resource
    A RACHITT for our toolbox (2001)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 19 (2001), S. 314-315 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Molecular evolution methodologies have proved immensely powerful for engineering proteins with desired properties through iterative rounds of mutagenesis without prior knowledge of structure or mechanism. One such method, DNA shuffling, exploits the recombination between genes to dramatically ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/86681
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Sequence-activity relationships guide directed evolution (2007)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 25 (2007), S. 297-298 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Directed evolution to improve the properties of proteins faces a problem of numbers: for an average-sized protein, the sequence space to be explored is astronomically large, whereas practical screening capacity is limited to thousands or millions of variants. Virtual screening in silico can analyze ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt0307-297
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    Paper (German National Licenses)
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